A concise route for the synthesis of biologically interesting pyranocoumarins - Seselin, (±)-cis-khellactone, (±)- quianhucoumarin D, and the (±)-5-deoxyprotobruceol-I regioisomer

Synthesis

Volumn , Issue 5, 2006, Pages 853-859

  Lee, Yong Rok ^a   Lee, Won Kyong ^a   Noh, Seok Kyun ^a   Lyoo, Won Seok ^a  

^a Yeungnam University   (South Korea)

Author keywords

Epoxides; Formylations; Nucleophiles; Pyranocoumarin derivatives; Ring opening

Indexed keywords

ISOMERS; SYNTHESIS (CHEMICAL);

FORMYLATIONS; NUCLEOPHILES; PYRANOCOUMARIN DERIVATIVES; RING-OPENING;

AROMATIC COMPOUNDS;

5 DEOXYPROTOBRUCEOL I; COUMARIN DERIVATIVE; EPOXIDE; KHELLACTONE; PYRAN DERIVATIVE; PYRANOCOUMARIN DERIVATIVE; QUIANHUCOUMARIN D; SESELIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMER; RING OPENING;

EID: 33644908856     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-926329     Document Type: Article

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45. 3): δ = 6.44 (1 H, d, J = 10.0 Hz), 5.16 (1 H, d, J = 10.0 Hz), 5.06 (1 H, t, J = 7.1 Hz), 2.40-2.33 (4 H, m), 2.03-1.93 (4 H, m), 1.75-1.68 (2 H, m), 1.65 (3 H, s), 1.54 (3 H, s), 1.34(3 H, s).