Cytotoxic naphthoquinones and plumbagic acid glucosides from Plumbago zeylanica

Phytochemistry

Volumn 62, Issue 4, 2003, Pages 619-622

  Lin, Lie Chwen ^a   Yang, Ling Ling ^a   Chou, Cheng Jen ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Coumarin; Cytotoxicity; Naphthoquinone; Plumbagic acid glucoside; Plumbaginaceae; Plumbago zeylanica

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 3' O BETA GLUCOPYRANOSYL PLUMBAGIC ACID METHYL ESTER; 5 METHOXYSESELIN; ANTINEOPLASTIC AGENT; CHITRANONE; COUMARIN DERIVATIVE; ELLIPTINONE; GLUCOSIDE; ISOSHINANOLONE; MARITINONE; NAPHTHOQUINONE; OXOACID; PLUMBAGIN; PLUMBAGO ZEYLANICA EXTRACT; SESELIN; SUBEROSIN; UNCLASSIFIED DRUG; XANTHOXYLETIN; XANTHYLETIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; INFRARED RADIATION; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; PLUMBAGINACEAE; RAJI CELL; TAIWAN; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; COUMARINS; GLUCOSIDES; HYDROLYSIS; INHIBITORY CONCENTRATION 50; KETO ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NAPHTHOQUINONES; PLANT ROOTS; PLUMBAGINACEAE; TAIWAN; TUMOR CELLS, CULTURED;

PLUMBAGINACEAE; PLUMBAGO; PLUMBAGO ZEYLANICA;

EID: 0037319816     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(02)00519-8     Document Type: Article

References (14)

1. Chiu, N.Y., Chang, K.H., 1986. The Illustrated Medicinal Plants of Taiwan, SMC, Taipei.
2. Dinda, B., Hajra, A.K., Das, S.K., 1998. Chemical constituents of Plumbago indica roots. Indian Journal of Chemistry 37B, 672- 675.
3. Dinda, B., Saha, S., 1989. A new binaphthoquinone from Plumbago zeylanica Linn. Indian Journal of Chemistry 28B, 984-986.
4. Gunaherath, G.M.K.B., Gunatilaka, A.A.L., Sultanbawa, M.U.S., Salasubramaniam, S., 1983. 1,2(3)-Tetrahydro-3,3′-biplumbagin: a naphthalenone and other constituents from Plumbago zeylanica. Phytochemistry 22, 1245-1247.
5. Gunaherath, G.M.K.B., Gunatilaka, A.A.L., 1988. Studies on medicinal and related plants of Sri Lanka. Part 18. Structure of a new naphthoquinone from Plumbago zeylanica. Journal of Chemical Society, Perkin Transaction 1, 407-410.
6. Ito, C., Matsuoka, M., Oka, T., Ju-ichi, M., Niwa, M., Omura, M., Furukawa, H., 1990. New binary coumarins from Citrus plants. Chemical Pharmaceutical Bulletin 38, 1230-1232.
7. Kuo, Y.C., Lin, C.Y., Tsai, W.J., Wu, C.L., Chen, C.F., Shiao, M.S., 1994. Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. Cancer Investigation 12, 611-615.
8. Li, H. L., 1998. Plumbaginaceae. In: Editorial Committee of the Flora of Taiwan (Eds.), Flora of Taiwan, second ed., Vol. IV. Editorial Committee of the Flora of Taiwan, pp 79-82.
9. Murray, R.D.H., Zeghdi, S., 1989. Synthesis of the natural coumarins, murraol (CM-c2), trans-dehydroosthol and swietenocoumarin G. Phytochemistry 28, 227-230.
10. Nayar, M.N.S., Bhan, M.K., 1972. Coumarins and other constituents of Hesperethusa crenulata. Phytochemistry 11, 3331-3333.
11. Sankaram, A.V.B., Srinivasarao, A., Sidhu, G.S., 1976. Chitranone - a new binaphthaquinone from Plumbago zeylanica. Phytochemistry 15, 237-238.
12. Tezuka, M., Takahashi, C., Kuroyanagi, M., Satake, M., Yoshihira, K., Natori, S., 1973. New naphthoquinone from Diospyros. Phytochemistry 12, 175-183.
13. Wu, T.S., Kuoh, C.H., Furukawa, H., 1983a. Acridone alkaloids and a coumarin from Citrus grandis. Phytochemistry 22, 1493-1497.
14. Wu, T.S., Kuoh, C.H., Furukawa, H., 1983b. Acridone alkaloids VI. The constituents of Citrus depressa. Isolation and structure elucidation of new acridone alkaloids from Citrus genus, Chemical Pharmaceutical Bulletin 31, 895-900.