Biological aspects of macrophage-stimulating protein (MSP) and its receptor

CIBA Foundation Symposia

Volumn , Issue 212, 1997, Pages 183-197

  Leonard, Edward J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GROWTH PROMOTOR; MACROPHAGE STIMULATING PROTEIN; ONCOPROTEIN; PROTEIN; PROTEIN PRECURSOR; PROTEIN TYROSINE KINASE; RON PROTEIN; SCATTER FACTOR;

ANIMAL; CHEMISTRY; CYTOLOGY; ECTODERM; EPITHELIUM CELL; HUMAN; HYDROLYSIS; MACROPHAGE; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMALS; ECTODERM; EPITHELIAL CELLS; GROWTH SUBSTANCES; HEPATOCYTE GROWTH FACTOR; HUMANS; HYDROLYSIS; MACROPHAGES; PROTEIN PRECURSORS; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE;

EID: 0031298720     PISSN: 03005208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Banu N, Price DJ, London R et al 1996 Modulation of megakaryocytopoiesis by human macrophage-stimulating protein, the ligand for the RON receptor. J Immunol 156:2933-2940
2. Bottaro DP, Rubin JS, Faletto DL et al 1991 Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251:802-804
3. Donate LE, Gherardi E, Srinivasan N, Sowdhamini R, Aparicio S, Blundell TL 1994 Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/ MSP). Protein Sci 3:2378-2394
4. Gaudino G, Follenzi A, Naldini L et al 1994 RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. EMBO J 13:3524-3532
5. Gaudino G, Avantaggiato V, Follenzi A, Acampora D, Simeone A, Comoglio PM 1995 The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues. Oncogene 11:2627-2637
6. Han S, Stuart LA, Degen SJF 1991 Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. Biochemistry 30:9768-9780
7. Iwama A, Okano K, Sudo T, Matsuda Y, Suda T 1994 Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched haematopoietic stem cells. Blood 83: 3160-3169
8. Iwama A, Wang M-H, Yamaguchi N et al 1995 Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage stimulating protein. Blood 86:3394-3403
9. Kurihara N, Iwama A, Tatsumi J, Ikeda K, Suda T 1996 Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells. Blood 87:3704-3710
10. Leonard EJ, Skeel A 1976 A serum protein that stimulates macrophage movement, chemotaxis and spreading. Exp Cell Res 102:434-438
11. Leonard EJ, Skeel A 1980 Functional differences between resident and exudate peritoneal mouse macrophages: specific serum protein requirements for responsiveness to chemotaxins. J Reticuloendothel Soc 28:437-447
12. Leonard EJ, Skeel A 1996 Hepatic catabolism of intravenously administered pro-macrophage-stimulating protein in mice. J Leukocyte Biol 60:453-458
13. Ohshiro K, Iwama A, Matsuno K et al 1996 Molecular cloning of rat macrophage-stimulating protein and its involvement in the male reproductive system. Biochem Biophys Res Commun 227:273-280
14. Quantin B, Schuhbaur B, Gesnel M-C, Dollé P, Breathnach R 1996 Restricted expression of the RON gene encoding the macrophage stimulating protein receptor during mouse development. Dev Dyn 204:383-390
15. Ronsin C, Muscatelli F, Mattei MG, Breathnach R 1993 A novel putative receptor protein tyrosine kinase of the met family. Oncogene 8:1195-1202
16. Skeel A, Yoshimura T, Showalter S, Tanaka S, Appella E, Leonard E 1991 Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity. J Exp Med 173:1227-1234
17. Wang M-H, Skeel A, Yoshimura T, Copeland TD, Sakaguchi K, Leonard EJ 1993 Antibodies to macrophage stimulating protein (MSP): specificity, epitope interactions, and immunoassay of MSP in human serum. J Leukocyte Biol 54:289-295
18. Wang M-H, Gonias SL, Skeel A, Wolf BB, Yoshimura T, Leonard EJ 1994a Proteolytic activation of single-chain precursor macrophage stimulating protein by nerve growth factor-γ and epidermal growth factor binding protein, members of the kallikrein family. J Biol Chem 269:13806-13810
19. Wang M-H, Ronsin C, Gesnel M-C et al 1994b Identification of the RON gene product as the receptor for the human macrophage stimulating protein. Science 266:117-119
20. Wang M-H, Yoshimura T, Skeel A, Leonard EJ 1994c Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade. J Biol Chem 269:3436-3440
21. Wang M-H, Iwama A, Skeel A, Suda T, Leonard EJ 1995 The murine STK gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage stimulating protein. Proc Natl Acad Sci USA 92:3933-3937
22. Wang M-H, Iwama A, Dlugosz AA et al 1996a Macrophage stimulating protein induces proliferation and migration of murine keratinocytes. Exp Cell Res 226:39-46
23. Wang M-H, Montero-Julian FA, Dauny I, Leonard EJ 1996b Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein. Oncogene 13:2167-2175
24. Wang M-H, Skeel A, Leonard EJ 1996c Proteolytic cleavage and activation of pro-macrophage stimulating protein by resident peritoneal macrophage membrane proteases. J Clin Invest 97:720-727
25. Wang M-H, Julian FM, Breathnach R et al 1997 Macrophage stimulating protein (MSP) binds to its receptor via the MSP β chain. J Biol Chem, 272:16999-17004
26. Yoshimura T, Yuhki N, Wang M-H, Skeel A, Leonard EJ 1993 Cloning, sequencing and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a kringle protein, and locates the gene on chromosome 3. J Biol Chem 268:15461-15468