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Volumn 570, Issue 2, 2006, Pages 355-374

Simulation of Ca2+ persistent inward currents in spinal motoneurones: Mode of activation and integration of synaptic inputs

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; POTASSIUM CHANNEL; SODIUM; CALCIUM; CALCIUM CHANNEL;

EID: 33644859593     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.099119     Document Type: Article
Times cited : (61)

References (47)
  • 1
    • 0031739279 scopus 로고    scopus 로고
    • Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats
    • Bennett DJ, Hultborn H, Fedirchuk B & Gorassini MA (1998). Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J Neurophysiol 80, 2023-2037.
    • (1998) J Neurophysiol , vol.80 , pp. 2023-2037
    • Bennett, D.J.1    Hultborn, H.2    Fedirchuk, B.3    Gorassini, M.A.4
  • 2
    • 0034786606 scopus 로고    scopus 로고
    • Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro
    • Bennett DJ, Li Y & Siu M (2001). Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro. J Neurophysiol 86, 1955-1971.
    • (2001) J Neurophysiol , vol.86 , pp. 1955-1971
    • Bennett, D.J.1    Li, Y.2    Siu, M.3
  • 3
    • 0027409375 scopus 로고
    • Quantitative synaptology of functionally different types of cat medial gastrocnemius alpha-motoneurons
    • Brannstrom T (1993). Quantitative synaptology of functionally different types of cat medial gastrocnemius alpha-motoneurons. J Comp Neurol 330, 439-454.
    • (1993) J Comp Neurol , vol.330 , pp. 439-454
    • Brannstrom, T.1
  • 4
    • 0026767858 scopus 로고
    • On the regulation of repetitive firing in lumbar motoneurones during fictive locomotion in the cat
    • Brownstone RM, Jordan LM, Kriellaars DJ, Noga BR & Shefchyk SJ (1992). On the regulation of repetitive firing in lumbar motoneurones during fictive locomotion in the cat. Exp Brain Res 90, 441-455.
    • (1992) Exp Brain Res , vol.90 , pp. 441-455
    • Brownstone, R.M.1    Jordan, L.M.2    Kriellaars, D.J.3    Noga, B.R.4    Shefchyk, S.J.5
  • 5
    • 0014127891 scopus 로고
    • Composite nature of the monosynaptic excitatory postsynaptic potential
    • Burke RE (1967). Composite nature of the monosynaptic excitatory postsynaptic potential. J Neurophysiol 30, 1114-1137.
    • (1967) J Neurophysiol , vol.30 , pp. 1114-1137
    • Burke, R.E.1
  • 6
    • 0029836794 scopus 로고    scopus 로고
    • Horseradish peroxidase study of the spatial and electrotonic distribution of group Ia synapses on type-identified ankle extensor motoneurons in the cat
    • Burke RE & Glenn LL (1996). Horseradish peroxidase study of the spatial and electrotonic distribution of group Ia synapses on type-identified ankle extensor motoneurons in the cat. J Comp Neurol 372, 465-485.
    • (1996) J Comp Neurol , vol.372 , pp. 465-485
    • Burke, R.E.1    Glenn, L.L.2
  • 7
    • 0018372228 scopus 로고
    • HRP anatomy of group Ia afferent contacts on alpha motoneurones
    • Burke RE, Walmsley B & Hodgson JA (1979). HRP anatomy of group Ia afferent contacts on alpha motoneurones. Brain Res 160, 347-352.
    • (1979) Brain Res , vol.160 , pp. 347-352
    • Burke, R.E.1    Walmsley, B.2    Hodgson, J.A.3
  • 8
    • 0023200815 scopus 로고
    • Membrane area and dendritic structure in type-identified triceps surae alpha motoneurons
    • Cullheim S, Fleshman JW, Glenn LL & Burke RE (1987). Membrane area and dendritic structure in type-identified triceps surae alpha motoneurons. J Comp Neurol 255, 68-81.
    • (1987) J Comp Neurol , vol.255 , pp. 68-81
    • Cullheim, S.1    Fleshman, J.W.2    Glenn, L.L.3    Burke, R.E.4
  • 9
    • 33645949295 scopus 로고    scopus 로고
    • Role of persistent inward currents (pics) in enhancement and integration of synaptic inputs in spinal motoneurons
    • Abstract Viewer/Itinerary Planner, Society for Neuroscience Washington, DC. Online. Program no. 750.4.2005
    • ElBasiouny SM, Bennett DJ & Mushahwar VK (2005 a). Role of persistent inward currents (pics) in enhancement and integration of synaptic inputs in spinal motoneurons. Abstract Viewer/Itinerary Planner, Society for Neuroscience, Washington, DC. Online. Program no. 750.4.2005.
    • (2005)
    • ElBasiouny, S.M.1    Bennett, D.J.2    Mushahwar, V.K.3
  • 11
    • 33645941688 scopus 로고    scopus 로고
    • Spatial distribution of low voltage-activated L-type calcium channels in the dendrites of cat lumbar motoneurons
    • Abstract Viewer/Itinerary Planner, Society for Neuroscience, Washington, DC. Online. Program no. 875.7.2004
    • ElBasiouny SM & Mushahwar VK (2004). Spatial distribution of low voltage-activated L-type calcium channels in the dendrites of cat lumbar motoneurons. Abstract Viewer/Itinerary Planner, Society for Neuroscience, Washington, DC. Online. Program no. 875.7.2004.
    • (2004)
    • ElBasiouny, S.M.1    Mushahwar, V.K.2
  • 12
    • 0023733789 scopus 로고
    • Electrotonic architecture of type-identified alpha-motoneurons in the cat spinal cord
    • Fleshman JW, Segev I & Burke RE (1988). Electrotonic architecture of type-identified alpha-motoneurons in the cat spinal cord. J Neurophysiol 60, 60-85.
    • (1988) J Neurophysiol , vol.60 , pp. 60-85
    • Fleshman, J.W.1    Segev, I.2    Burke, R.E.3
  • 13
    • 0025887302 scopus 로고
    • Spatial distribution of recurrent inhibitory synapses on spinal motoneurons in the cat
    • Fyffe RE (1991). Spatial distribution of recurrent inhibitory synapses on spinal motoneurons in the cat. J Neurophysiol 65, 1134-1149.
    • (1991) J Neurophysiol , vol.65 , pp. 1134-1149
    • Fyffe, R.E.1
  • 14
    • 0004713925 scopus 로고
    • Estimates of electrotonic distance of group Ia contacts on cat α-motoneurons: An HRP-morphological study
    • Glenn LL, Burke RE, Fleshman JW & Lev-Tov A (1982). Estimates of electrotonic distance of group Ia contacts on cat α-motoneurons: An HRP-morphological study. Soc Neurosci Abstr 8, 995.
    • (1982) Soc Neurosci Abstr , vol.8 , pp. 995
    • Glenn, L.L.1    Burke, R.E.2    Fleshman, J.W.3    Lev-Tov, A.4
  • 15
    • 0036092734 scopus 로고    scopus 로고
    • Intrinsic activation of human motoneurons: Possible contribution to motor unit excitation
    • Gorassini MA, Yang JF, Siu M & Bennett DJ (2002). Intrinsic activation of human motoneurons: Possible contribution to motor unit excitation. J Neurophysiol 87, 1850-1858.
    • (2002) J Neurophysiol , vol.87 , pp. 1850-1858
    • Gorassini, M.A.1    Yang, J.F.2    Siu, M.3    Bennett, D.J.4
  • 16
    • 0013965084 scopus 로고
    • Algebraical summation in synaptic activation of motoneurones firing within the 'primary range' to injected currents
    • Granit R, Kernell D & Lamarre Y (1966 a). Algebraical summation in synaptic activation of motoneurones firing within the 'primary range' to injected currents. J Physiol 187, 379-399.
    • (1966) J Physiol , vol.187 , pp. 379-399
    • Granit, R.1    Kernell, D.2    Lamarre, Y.3
  • 17
    • 0013970077 scopus 로고
    • Synaptic stimulation superimposed on motoneurones firing in the 'secondary range' to injected current
    • Granit R, Kernell D & Lamarre Y (1966 b). Synaptic stimulation superimposed on motoneurones firing in the 'secondary range' to injected current. J Physiol 187, 401-415.
    • (1966) J Physiol , vol.187 , pp. 401-415
    • Granit, R.1    Kernell, D.2    Lamarre, Y.3
  • 18
    • 0024267456 scopus 로고
    • Analysis of effective synaptic currents generated by homonymous Ia afferent fibers in motoneurons of the cat
    • Heckman CJ & Binder MD (1988). Analysis of effective synaptic currents generated by homonymous Ia afferent fibers in motoneurons of the cat. J Neurophysiol 60, 1946-1966.
    • (1988) J Neurophysiol , vol.60 , pp. 1946-1966
    • Heckman, C.J.1    Binder, M.D.2
  • 19
    • 13244298118 scopus 로고    scopus 로고
    • Persistent inward currents in motoneuron dendrites: Implications for motor output
    • Heckman CJ, Gorassini MA & Bennett DJ (2005). Persistent inward currents in motoneuron dendrites: Implications for motor output. Muscle Nerve 31, 135-156.
    • (2005) Muscle Nerve , vol.31 , pp. 135-156
    • Heckman, C.J.1    Gorassini, M.A.2    Bennett, D.J.3
  • 20
    • 0031571202 scopus 로고    scopus 로고
    • The NEURON simulation environment
    • Hines M & Carnevale T (1997). The NEURON simulation environment. Neural Comput 9, 1179-1209.
    • (1997) Neural Comput , vol.9 , pp. 1179-1209
    • Hines, M.1    Carnevale, T.2
  • 21
    • 0023780272 scopus 로고
    • Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan
    • Hounsgaard J, Hultborn H, Jespersen B & Kiehn O (1988). Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan. J Physiol 405, 345-367.
    • (1988) J Physiol , vol.405 , pp. 345-367
    • Hounsgaard, J.1    Hultborn, H.2    Jespersen, B.3    Kiehn, O.4
  • 22
    • 0024319735 scopus 로고
    • Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential
    • Hounsgaard J & Kiehn O (1989). Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential. J Physiol 414, 265-282.
    • (1989) J Physiol , vol.414 , pp. 265-282
    • Hounsgaard, J.1    Kiehn, O.2
  • 23
    • 0023856933 scopus 로고
    • Calcium conductance and firing properties of spinal motoneurones in the turtle
    • Hounsgaard J & Mintz I (1988). Calcium conductance and firing properties of spinal motoneurones in the turtle. J Physiol 398, 591-603.
    • (1988) J Physiol , vol.398 , pp. 591-603
    • Hounsgaard, J.1    Mintz, I.2
  • 24
    • 0242624495 scopus 로고    scopus 로고
    • Variable amplification of synaptic input to cat spinal motoneurones by dendritic persistent inward current
    • Hultborn H, Denton ME, Wienecke J & Nielsen JB (2003). Variable amplification of synaptic input to cat spinal motoneurones by dendritic persistent inward current. J Physiol 552, 945-952.
    • (2003) J Physiol , vol.552 , pp. 945-952
    • Hultborn, H.1    Denton, M.E.2    Wienecke, J.3    Nielsen, J.B.4
  • 25
    • 0002649098 scopus 로고
    • The adaptation and the relation between discharge frequency and current strength of cat lumbosacral motoneurones stimulated by long-lasting injected currents
    • Kernell D (1965 a). The adaptation and the relation between discharge frequency and current strength of cat lumbosacral motoneurones stimulated by long-lasting injected currents. Acta Physiol Scand 65, 65-73.
    • (1965) Acta Physiol Scand , vol.65 , pp. 65-73
    • Kernell, D.1
  • 26
    • 84979126209 scopus 로고
    • High-frequency repetitive firing of cat lumbosacral motoneurones stimulated by long-lasting injected currents
    • Kernell D (1965 b). High-frequency repetitive firing of cat lumbosacral motoneurones stimulated by long-lasting injected currents. Acta Physiol Scand 65, 74-86.
    • (1965) Acta Physiol Scand , vol.65 , pp. 74-86
    • Kernell, D.1
  • 27
    • 0006670774 scopus 로고
    • Synaptic influence on the repetitive activity elicited in cat lumbosacral motoneurones by long-lasting injected currents
    • Kernell D (1965 c). Synaptic influence on the repetitive activity elicited in cat lumbosacral motoneurones by long-lasting injected currents. Acta Physiol Scand 63, 409-410.
    • (1965) Acta Physiol Scand , vol.63 , pp. 409-410
    • Kernell, D.1
  • 28
    • 0014496901 scopus 로고
    • Non-linear summation of unit synaptic potentials in spinal motoneurones of the cat
    • Kuno M & Miyahara JT (1969). Non-linear summation of unit synaptic potentials in spinal motoneurones of the cat. J Physiol 201, 465-477.
    • (1969) J Physiol , vol.201 , pp. 465-477
    • Kuno, M.1    Miyahara, J.T.2
  • 29
    • 0031866154 scopus 로고    scopus 로고
    • Bistability in spinal motoneurons in vivo: Systematic variations in rhythmic firing patterns
    • Lee RH & Heckman CJ (1998 a). Bistability in spinal motoneurons in vivo: Systematic variations in rhythmic firing patterns. J Neurophysiol 80, 572-582.
    • (1998) J Neurophysiol , vol.80 , pp. 572-582
    • Lee, R.H.1    Heckman, C.J.2
  • 30
    • 0031813246 scopus 로고    scopus 로고
    • Bistability in spinal motoneurons in vivo: Systematic variations in persistent inward currents
    • Lee RH & Heckman CJ (1998 b). Bistability in spinal motoneurons in vivo: Systematic variations in persistent inward currents. J Neurophysiol 80, 583-593.
    • (1998) J Neurophysiol , vol.80 , pp. 583-593
    • Lee, R.H.1    Heckman, C.J.2
  • 31
    • 0032720947 scopus 로고    scopus 로고
    • Paradoxical effect of QX-314 on persistent inward currents and bistable behavior in spinal motoneurons in vivo
    • Lee RH & Heckman CJ (1999). Paradoxical effect of QX-314 on persistent inward currents and bistable behavior in spinal motoneurons in vivo. J Neurophysiol 82, 2518-2527.
    • (1999) J Neurophysiol , vol.82 , pp. 2518-2527
    • Lee, R.H.1    Heckman, C.J.2
  • 32
    • 0034279110 scopus 로고    scopus 로고
    • Adjustable amplification of synaptic input in the dendrites of spinal motoneurons in vivo
    • Lee RH & Heckman CJ (2000). Adjustable amplification of synaptic input in the dendrites of spinal motoneurons in vivo. J Neurosci 20, 6734-6740.
    • (2000) J Neurosci , vol.20 , pp. 6734-6740
    • Lee, R.H.1    Heckman, C.J.2
  • 33
    • 0037252958 scopus 로고    scopus 로고
    • Influence of active dendritic currents on input-output processing in spinal motoneurons in vivo
    • Lee RH, Kuo JJ, Jiang MC & Heckman CJ (2003). Influence of active dendritic currents on input-output processing in spinal motoneurons in vivo. J Neurophysiol 89, 27-39.
    • (2003) J Neurophysiol , vol.89 , pp. 27-39
    • Lee, R.H.1    Kuo, J.J.2    Jiang, M.C.3    Heckman, C.J.4
  • 34
    • 0041816000 scopus 로고    scopus 로고
    • Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats
    • Li Y & Bennett DJ (2003). Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats. J Neurophysiol 90, 857-869.
    • (2003) J Neurophysiol , vol.90 , pp. 857-869
    • Li, Y.1    Bennett, D.J.2
  • 35
    • 0842327877 scopus 로고    scopus 로고
    • Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats
    • Li Y, Gorassini MA & Bennett DJ (2004). Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats. J Neurophysiol 91, 767-783.
    • (2004) J Neurophysiol , vol.91 , pp. 767-783
    • Li, Y.1    Gorassini, M.A.2    Bennett, D.J.3
  • 36
    • 0029125828 scopus 로고
    • Effective synaptic current and motoneuron firing rate modulation
    • Powers RK & Binder MD (1995). Effective synaptic current and motoneuron firing rate modulation. J Neurophysiol 74, 793-801.
    • (1995) J Neurophysiol , vol.74 , pp. 793-801
    • Powers, R.K.1    Binder, M.D.2
  • 37
    • 0033957714 scopus 로고    scopus 로고
    • Summation of effective synaptic currents and firing rate modulation in cat spinal motoneurons
    • Powers RK & Binder MD (2000). Summation of effective synaptic currents and firing rate modulation in cat spinal motoneurons. J Neurophysiol 83, 483-500.
    • (2000) J Neurophysiol , vol.83 , pp. 483-500
    • Powers, R.K.1    Binder, M.D.2
  • 38
  • 39
    • 0035181265 scopus 로고    scopus 로고
    • Amplification and linear summation of synaptic effects on motoneuron firing rate
    • Prather JF, Powers RK & Cope TC (2001). Amplification and linear summation of synaptic effects on motoneuron firing rate. J Neurophysiol 85, 43-53.
    • (2001) J Neurophysiol , vol.85 , pp. 43-53
    • Prather, J.F.1    Powers, R.K.2    Cope, T.C.3
  • 40
    • 0024331045 scopus 로고
    • Physiological properties of the motor units of the wrist extensor muscles in man
    • Romaiguere P, Vedel JP, Pagni S & Zenatti A (1989). Physiological properties of the motor units of the wrist extensor muscles in man. Exp Brain Res 78, 51-61.
    • (1989) Exp Brain Res , vol.78 , pp. 51-61
    • Romaiguere, P.1    Vedel, J.P.2    Pagni, S.3    Zenatti, A.4
  • 41
    • 0033396810 scopus 로고    scopus 로고
    • Non-linear summation of synaptic currents on spinal motoneurons: Lessons from simulations of the behaviour of anatomically realistic models
    • Rose PK & Cushing S (1999). Non-linear summation of synaptic currents on spinal motoneurons: Lessons from simulations of the behaviour of anatomically realistic models. Prog Brain Res 123, 99-107.
    • (1999) Prog Brain Res , vol.123 , pp. 99-107
    • Rose, P.K.1    Cushing, S.2
  • 42
    • 0029053214 scopus 로고
    • Spike frequency adaptation studied in hypoglossal motoneurons of the rat
    • Sawczuk A, Powers R & Binder MD (1995). Spike frequency adaptation studied in hypoglossal motoneurons of the rat. J Neurophysiol 73, 1799-1810.
    • (1995) J Neurophysiol , vol.73 , pp. 1799-1810
    • Sawczuk, A.1    Powers, R.2    Binder, M.D.3
  • 43
    • 0017340465 scopus 로고
    • A persistent negative resistance in cat lumbar motoneurons
    • Schwindt PC & Crill WE (1977). A persistent negative resistance in cat lumbar motoneurons. Brain Res 120, 173-178.
    • (1977) Brain Res , vol.120 , pp. 173-178
    • Schwindt, P.C.1    Crill, W.E.2
  • 44
    • 0019988028 scopus 로고
    • Factors influencing motoneuron rhythmic firing: Results from a voltage-clamp study
    • Schwindt PC & Crill WE (1982). Factors influencing motoneuron rhythmic firing: Results from a voltage-clamp study. J Neurophysiol 48, 875-890.
    • (1982) J Neurophysiol , vol.48 , pp. 875-890
    • Schwindt, P.C.1    Crill, W.E.2
  • 45
    • 0025085615 scopus 로고
    • Computer simulation of group Ia EPSPs using morphologically realistic models of cat alpha-motoneurons
    • Segev I, Fleshman JW & Burke RE (1990). Computer simulation of group Ia EPSPs using morphologically realistic models of cat alpha-motoneurons. J Neurophysiol 64, 648-660.
    • (1990) J Neurophysiol , vol.64 , pp. 648-660
    • Segev, I.1    Fleshman, J.W.2    Burke, R.E.3
  • 46
    • 0015503803 scopus 로고
    • Extrapyramidal monosynaptic and disynaptic control of mammalian alpha-motoneurons
    • Shapovalov AI (1972). Extrapyramidal monosynaptic and disynaptic control of mammalian alpha-motoneurons. Brain Res 40, 105-115.
    • (1972) Brain Res , vol.40 , pp. 105-115
    • Shapovalov, A.I.1
  • 47
    • 0031892533 scopus 로고    scopus 로고
    • Transmitter regulation of plateau properties in turtle motoneurons
    • Svirskis G & Hounsgaard J (1998). Transmitter regulation of plateau properties in turtle motoneurons. J Neurophysiol 79, 45-50.
    • (1998) J Neurophysiol , vol.79 , pp. 45-50
    • Svirskis, G.1    Hounsgaard, J.2


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