Regulation of sexual behaviour in male macaques by sex steroid modulation of the serotonergic system

Experimental Physiology

Volumn 91, Issue 2, 2006, Pages 445-456

  Barrett, Gordon M ^a,c   Bardi, Massimo ^b   Guillén, Ana Karina Zavala ^a   Mori, Akio ^a   Shimizu, Keiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF RICHMOND   (United States)

^c OTTAWA REGIONAL CANCER CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; ANDROSTANOLONE; ESTRADIOL; ESTRADIOL CIPIONATE; PROGESTERONE; SEROTONIN; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TRYPTOPHAN;

AMINO ACID BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; EJACULATION; ESTRADIOL BLOOD LEVEL; ESTROGEN ACTIVITY; FEMALE; GROOMING; HORMONAL REGULATION; HORMONE BLOOD LEVEL; MACACA; MALE; NONHUMAN; PROGESTERONE BLOOD LEVEL; REGRESSION ANALYSIS; REGULATORY MECHANISM; SEROTONIN BLOOD LEVEL; SEROTONINERGIC SYSTEM; SEXUAL BEHAVIOR; TESTOSTERONE BLOOD LEVEL;

EID: 33644832721     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2005.032193     Document Type: Article

References (63)

1. Althof S Levine S Corty E Risen C & Stern E 1994 The role of clomipramine in the treatment of premature ejaculation J Urol 151 345A
2. Amin Z Canli T & Epperson CN 2005 Effect of estrogen-serotonin interactions on mood and cognition Behav Cogn Neurosci Rev 4 43 58
3. Anderson GM Young JG Cohen DJ Schlicht KR & Patel N 1981 Liquid-chromatographic determination of serotonin and tryptophan in whole blood and plasma Clin Chem 27 775 776
4. Banki CM 1978 5-Hydroxytryptamine content of the whole blood in psychiatric illness and alcoholism Acta Psychiat Scand 57 232 238
5. Barrett GM Shimizu K Bardi M Asaba S & Mori A 2002 Endocrine correlates of rank, reproduction and female- directed aggression in male Japanese macaques (Macaca fuscata) Horm Behav 42 85 96
6. Bender DA 1983 Biochemistry of tryptophan in health and disease Mol Aspects Med 6 101 197
7. Bercovitch FB Goy RW Scheffler G Wittwer DJ & Hempel M 1987 A benign method for maintaining ovulatory oestrogen levels in cycling rhesus macaques Am J Primatol 13 67 72
8. Bethea CL Lu NZ Gundlah C & Streicher JM 2002 Diverse actions of ovarian steroids in the serotonin neural system Front Neuroendocrin 23 41 100
9. Carani C Qin K Simoni M Faustini-Fustini M Serpente S Boyd J Korach KS & Simpson ER 1997 Effect of testosterone and estradiol in a man with aromatase deficiency New Engl J Med 337 91 95
10. Carani C Rochira V Faustini-Fustini M Balestrieri A & Granata ARM 1999 Role of oestrogen in male sexual behaviour: insights from the natural model of aromatase deficiency Clin Endocrinol 51 517 524
11. Cassidenti DL Paulson RJ Serafini P Stanczyk FZ & Lobo RA 1991 Effects of sex steroids on skin 5α-reductase activity in vitro Obstet Gynecol 78 103 107
12. Cornil CA Dalla C Papadopoulou-Daifoti Z Baillien M & Balthazart J 2006 Estradiol rapidly activates male sexual behavior and affects brain monoamine levels in the quail brain Behav Brain Res 166 110 123
13. Daels PF Albrecht BA & Mohammed HO 1998 Equine chorionic gonadotropin regulates luteal steroidogenesis in pregnant mares Biol Reprod 59 1062 1068
14. Dukes M Edwards PN Large M Smith IK & Boyle T 1996 The preclinical pharmacology of 'Arimidex' (anastrozole; ZD1033) - a potent, selective aromatase inhibitor J Steroid Biochem Mol Biol 58 439 445
15. Everitt B 1990 Sexual motivation: a neural and behavioural analysis of the mechanisms underlying appetitive and copulatory responses of male rats Neurosci Biobehav Rev 14 219 232
16. Fernstrom JD & Wurtman RJ 1971 Brain serotonin content: physiological dependence on plasma tryptophan levels Science 173 149 151
17. Fink G Sumner B Rosie R Wilson H & McQueen J 1999 Androgen actions on central serotonin neurotransmission: relevance for mood, mental state and memory Behav Brain Res 105 53 68
18. Fisher CR Graves KH Parlow AF & Simpson ER 1998 Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp 19 gene Proc Natl Acad Sci U S A 95 6965 6970
19. Hinde RA & Atkinson S 1970 Assessing the roles of social partners in maintaining mutual proximity, as exemplified by mother-infant relations in rhesus monkeys Anim Behav 18 169 176
20. Jacobs BL & Azmitia EC 1992 Structure and function of the brain serotonin system Physiol Rev 72 165 229
21. Jequier E Robinson DS Lovenberg W & Sjoerdsma A 1969 Further studies on tryptophan hydroxylase in rat brain and beef pineal Biochem Pharmacol 18 1071 1081
22. Kompoliti K Chu Y Polish A Roberts J McKay H Mufson EJ Leurgans S Morrison JH & Kordower JH 2004 Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys J Comp Neurol 472 193 207
23. Krieg M Schlenker A & Voight K 1985 Inhibition of androgen metabolism in stroma and epithelium of the human benign prostatic hyperplasia by progesterone, estrone, and estradiol Prostate 6 233 240
24. Lephart ED 1993 Brain 5α-reductase: cellular, enzymatic, and molecular perspectives and implications for biological function Mol Cell Neurosci 4 474 484
25. McEwen BS 1999 The molecular and neuroanatomical basis for oestrogen effects in the central nervous system J Clin Endocrinol Metab 84 1790 1797
26. McEwen BS & Alves SE 1999 Estrogen actions in the central nervous system Endocr Rev 20 279 307
27. McKinney J Knappskog PM & Haavik J 2005 Different properties of the central and peripheral forms of human tryptophan hydroxylase J Neurochem 92 311 320
28. McQueen JK Wilson H Sumner BEH & Fink G 1999 Serotonin transporter (SERT) mRNA and binding site densities in male rat brain affected by sex steroids Mol Brain Res 63 241 247
29. Malyszko J Urano T Serizawa K Yan D Kozima Y Takada Y & Takada A 1993 Serotonergic measures in blood and brain and their correlations in rats treated with tranylcypromine, a monoamine-oxidase inhibitor Jpn J Physiol 43 613 626
30. Mann JJ McBride PA Anderson GM & Mieczkowski TA 1992 Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and lifetime psychopathology Biol Psychiat 32 243 257
31. Mehlman PT Higley JD Fernald BJ Sallee FR Suomi SJ & Linnoila M 1997 CSF 5-HIAA, testosterone, and sociosexual behaviours in free-ranging male rhesus macaques in the mating season Psychiat Res 72 89 102
32. Moffitt TE Brammer GL Caspi A Fawcett JP Raleigh M Yuwiler A & Silva P 1998 Whole blood serotonin relates to violence in an epidemiological study Biol Psychiat 43 446 457
33. Morishima A Grumbach MM Simpson ER Fisher C & Qin K 1995 Aromatase deficiency in male and female sibling caused by a novel mutation and the physiological role of estrogens J Clin Endocrinol Metab 80 3689 3699
34. Ogawa S Chester AE Hewitt SC Walker VR Gustafsson J Smithies O Korach KS & Pfaff DW 2000 Abolition of male sexual behaviors in mice lacking estrogen receptors α and β (αβERKO) Proc Natl Acad Sci U S A 97 14737 14741
35. Pfeffer CR McBride A Anderson GM Kakuma T Fensterheim L & Khait V 1998 Peripheral serotonin measures in prepubertal psychiatric inpatients and normal children: associations with suicidal behaviour and its risk factors Biol Psychiat 44 568 577
36. Phelps SM Lydon JP O'Malley BW & Crews D 1998 Regulation of male sexual behavior by progesterone receptor, sexual experience and androgen Horm Behav 34 294 302
37. Quintana J 1992 Platelet serotonin and plasma tryptophan decreases in endogenous depression: clinical, therapeutic, and biological correlations J Affect Disorders 24 55 62
38. Raleigh MJ Yuwiler A Brammer GL McGuire MT Geller E & Flannery JW 1981 Peripheral correlates of serotonergically-influenced behaviours in vervet monkeys (Cercopithecus aethiops sabaeus) Psychopharmacology 72 241 246
39. Robbins A 1996 Androgens and male sexual behavior from mice to men Trends Endocrinol Metab 7 345 350
40. Rosen RC Lane RM & Menza M 1999 Effects of SSRIs on sexual function: a critical review J Clin Psychopharmacol 19 67 85
41. Russo S Kema IP Fokkema MR Boon JC Willemse PHB de Vries EG den Boer JA & Korf J 2003 Tryptophan as a link between psychopathology and somatic states Psychosom Med 65 665 671
42. Sachenko VV & Khorevin VI 2001 Serotonin and central mechanisms underlying motor control Neurophysiology 33 180 196
43. Sharpe RM 1998 The roles of oestrogen in the male Trends Endocrinol Metab 9 371 377
44. Smith EP Boyd J Frank RG Takahashi H Cohen RM Specker B Williams TC Lubahn DB & Korach KS 1994 Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man New Engl J Med 16 1056 1106
45. Södergard R Bäckström T Shanbhag V & Carstensen H 1982 Calculation of free and bound fractions of testosterone and estradiol 17β to human plasma protein at body temperature J Steroid Biochem 26 801 810
46. Soltis J Mitsunaga F Shimizu K Nozaki M Yanagihara Y Domingo-Roura X & Takenaka O 1997a Sexual selection in Japanese macaques II: female mate choice and male-male competition Anim Behav 54 737 746
47. Soltis J Mitsunaga F Shimizu K Yanagihara Y & Nozaki M 1997b Sexual selection in Japanese macaques I: female mate choice or male sexual coercion Anim Behav 54 725 736
48. Stahl SM & Meltzer HY 1978 A kinetic and pharmacological analysis of 5-hydroxytryptamine transport by human platelets and platelet comparison with central serotonergic neurons J Pharmacol Exp Ther 205 118 132
49. 2A receptor mRNA and binding site densities in the male rat brain Mol Brain Res 59 205 214
50. Vermeulen A Verdonck L & Kaufman JM 1999 A critical evaluation of simple methods for the estimation of free testosterone in serum J Clin Endocrinol Metab 84 3666 3672
51. Wagner EJ Rønnekleiv OK Bosch MA & Kelly MJ 2001 Estrogen biphasically modifies hypothalamic GABAergic function concomitantly with negative and positive control of luteinizing hormone release J Neurosci 21 2085 2093
52. Wallen K 2001 Sex and context: hormones and primate sexual motivation Horm Behav 40 339 357
53. Walther D & Bader M 2003 A unique central tryptophan hydroxylase isoform Biochem Pharmacol 66 1673 1680
54. Wilson JD 1975 Metabolism of testicular androgens In Handbook of Physiology vol. 5 ed. Greep RO & Astwood EB chapter 25, section 7, pp. 491 508 American Physiological Society Washington DC
55. Wilson JD 1999 The role of androgens in male gender role behaviour Endocrine Rev 20 726 737
56. Wingrove J Bond AJ Cleare AJ & Sherwood R 1999 Plasma tryptophan and trait aggression J Psychopharmacol 13 235 237
57. Witt DM Reigada LC & Wengroff BE 1997 Intrahypothalamic progesterone regulates androgen- dependent sexual behavior in male rats Soc Neurosci Abstract 23 1357
58. Witt DM Young L & Crews D 1995 Progesterone modulation of androgen-dependent sexual behavior in male rats Physiol Behav 57 307 313
59. Yan D Urano T Pietraszek MH Shimoyama I Uemura K Kojima Y Sakakibara K Serizawa K Takada Y & Takada A 1993 Correlation between serotonergic measures in cerebrospinal fluid and blood of subhuman primate Life Sci 52 745 749
60. Young SN Smith SE Pihl R & Ervin FR 1985 Tryptophan depletion causes a rapid lowering of mood in normal males Psychopharmacology 87 173 177
61. Zumpe D Bonsall RW & Michael RP 1993 Effects of the nonsteroidal aromatase inhibitor, fadrozole, on the sexual behavior of male cynomologus monkeys (Macaca fascicularis) Horm Behav 27 200 215
62. Zumpe D Clancy AN & Michael RP 1997 Effects of progesterone on the sexual behavior of castrated, testosterone-treated male cynomolgus monkeys (Macaca fascicularis) Physiol Behav 62 61 67
63. Zumpe D Clancy AN & Michael RP 2001 Progesterone decreases mating and estradiol uptake in preoptic areas of male monkeys Physiol Behav 74 603 612