CTL responses induced by a single immunization with peptide encapsulated in biodegradable microparticles

Journal of Immunological Methods

Volumn 206, Issue 1-2, 1997, Pages 143-151

  Partidos, C D ^a   Vohra, P ^b   Jones, D ^c   Farrar, G ^c   Steward, M W ^b  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

CTL responses; Measles virus; PLG microparticles

Indexed keywords

ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; BIODEGRADATION; CYTOTOXIC T LYMPHOCYTE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; CARRIER PROTEINS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EPITOPES; LACTIC ACID; MEASLES VIRUS; MICE; MICE, INBRED A; MICE, INBRED CBA; MICROSPHERES; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; NUCLEOPROTEINS; PEPTIDE FRAGMENTS; POLYGLYCOLIC ACID; POLYMERS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; VACCINATION; VIRAL PROTEINS;

ANIMALIA; MEASLES VIRUS;

EID: 0030782958     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(97)00102-6     Document Type: Article

References (39)

1. Aguado, M.T., Lambert, P.H., 1992. Controlled-release vaccines. Biodegradable polylactide-polyglycolide (PL/PG) microspheres as antigen vehicles. Immunobiology 184, 113-125.
2. Alonso, M.J., Gupta, R.K., Min, C., Siber, G.R., Longer, R., 1994. Biodegradable microspheres as controlled release tetanus toxoid delivery systems. Vaccine 12, 299.
3. Coombes, A.G.A., Lavelle, E.C., Jenkins, P.G., Davis, S.S., 1996. Single dose, polymeric, microparticle-based vaccines: The influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen. Vaccine 14 (15), 1429.
4. Deres, K., Schild, H., Weismuller, K.H., Jung, G., Rammensee, H.G., 1989. In vivo priming of virus specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature 342, 561.
5. Eldridge, J.H., Staas, J.K., Meulbroek, J.A., Tice, T.R., Gilley, R.M., 1991a. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect. Immun. 59, 2978.
6. Eldridge, J.H., Staas, J.K., Meulbroek, J.A., McGhee, J.R., Tice, T.R., Gilley, R.M., 1991b. Biodegradable microspheres as a vaccine delivery system. Mol. Immunol. 28, 287.
7. Falk, K., Rotzschke, O., Stevanovic, S., Jung, G., Rammensee, H.-G., 1991. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351, 290.
8. Gopas, J., Itzhaky, D., Segev, Y., Salzberg, S., Trink, B., Isakov, N., Rager-Zisman, B., 1992. Persistent measles virus infection enhances major histocompatibility complex class I expression and immunogenicity of murine neuroblastoma cells. Cancer Immunol. Immunother. 34, 313.
9. Hora, M.S., Rana, R.K., Nunberg, J.H., Tice, T.R., Gilley, R.M., Hudson, M.E., 1990. Release of human serum albumin from poly(lactide-co-glycolide) microspheres. Pharm. Res. 7, 1190.
10. Hsu, S.-C., Shaw, D.M., Steward, M.W., 1995. The induction of respiratory syncytial virus specific cytotoxic T-cell responses following immunization with a synthetic peptide containing a fusion peptide linked to a cytotoxic T-lymphocyte epitope. Immunology 85 (3), 347.
11. Hsu, S.-C., Schadeck, E.B., Delmas, A., Shaw, M., Steward, M.W., 1996. Linkage of a fusion peptide to a CTL epitope from the nucleoprotein of measles virus enables incorporation into ISCOMs and induction of CTL responses following intranasal immunization. Vaccine 14 (12), 1159.
12. Jones, D.H., McBride, B.W., Jeffery, H., O'Hagan, D.T., Robinson, A., Farrar, G.H., 1995. Protection of mice from Bordetella pertussis respiratory infection using microencapsulated pertussis fimbriae. Vaccine 13, 675.
13. Jones, D.H., Corris, S., McDonald, S., Clegg, J.C.S., Farrar, G.H., 1997. Poly(DL-lactide-co-glycolide) encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration. Vaccine 15, 814.
14. Kast, W.M., Roux, L., Curren, J., Blom, H.J.J., Voordouw, A.C., Meloen, R.H., Kolakofsky, D., Melief, C.J.M., 1991. Protection against lethal Sendai virus infection by in vivo priming of virus specific cytotoxic T lymphocytes with a free synthetic peptide. Proc. Natl. Acad. Sci. USA 88, 2283.
15. Kreth, H.W., ter Meulen, V., Eckert, G., 1979. Demonstration of HLA restricted killer cells in patients with acute measles. Med. Microbiol. Immunol. 165, 203.
16. Layton, G.T., Harris, S.J., Gearing, A.J.H., Hill-Perkins, M., Cole, J.S., Griffiths, J.C., Burns, N.R., Kingsman, A., Adams, S.E., 1993. Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus like particles. J. Immunol. 151, 1097.
17. Lucas, C.J., Biddison, W.E., Nelson, D.L., Shaw, S., 1982. Killing of measles virus-infected cells by human cytotoxic T cells. Infect. Immunol. 38, 226.
18. Marx, P.A., Compans, R.W., Gettie, Staas, J.K., Gilley, R.M., Mulligan, M.J., Yamshchikov, G.V., Chen, D., Eldridge, J.H., 1993. Protection against vaginal SIV transmission with microencapsulated vaccine. Science 260, 1323.
19. Men, Y., Gander, B., Merkle, H.P., Corradin, G., 1996. Induction of sustained and elevated immune responses to weakly immunogenic synthetic malarial peptides by encapsulation in biodegradable polymer microspheres. Vaccine 14 (15), 1442.
20. Miller, R.A., Brady, J.M., Cutwright, D.E., 1977. Degradation rates of resorbable implants (polylactides and polyglycolides): Rate modification with changes in PLA/PLGA copolymer ratios. J. Biomed. Mater. Res. 11, 715.
21. Nair, S., Zhou, F., Reddy, R., Huang, L., Rouse, B.T., 1992. Soluble protein delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro. J. Exp. Med. 175, 609.
22. Nair, S., Buiting, A.M.J., Rouse, R.J.D., van Rooijen, N., Huang, L., Rouse, B.T., 1995. Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses. Int. Immunol. 7, 679.
23. Nixon, D.F., Hioe, C., Chen, P., Bian, Z., Kuebler, P., Li, M.-L., Oiu, H., Li, X.-M., Singh, M., Richardson, J., McGee, P., Zamb, T., Koff, W., Wang, C.Y., O'Hagan, D., 1996. Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity. Vaccine 14 (16), 1523.
24. O'Hagan, D.T., Jeffery, H., Davis, S.S., 1993. Long term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles. Vaccine 11, 965.
25. Partidos, C.D., Steward, M.W., 1990. Prediction and identification of a T cell epitope in the fusion protein of measles virus immunodominant in mice and humans. J. Gen. Virol. 71, 2099.
26. Partidos, C.D., Shaw, D.M., Gander, G., Merkle, H.P., Howard, C.R., Steward, M.W., 1994. Induction of antibody responses to a synthetic peptide entrapped in biodegradable microparticles. Vaccine Res. 3, 203.
27. Partidos, C.D., Vohra, P., Steward, M.W., 1996a. Induction of measles virus specific cytotoxic T cell responses after intranasal immunization with synthetic peptides. Immunology 87, 179.
28. Partidos, C.D., Vohra, P., Steward, M.W., 1996b. Priming of measles virus-specific CTL responses after immunization with a CTL epitope linked to a fusogenic peptide. Virology 215, 107.
29. Partidos, C.D., Vohra, P., Jones, D.H., Farrar, G.H., Steward, M.W., 1996c. Mucosal immunization with a measles virus CTL epitope encapsulated in biodegradable PLG microparticles. J. Immunol. Meth. 195, 135.
30. Partidos, C.D., Vohra, P., Anagnostopoulou, C., Jones, D.H., Farrar, G.H., Steward, M.W., 1996d. Biodegradable microparticles as a delivery system for measles virus cytotoxic T cell epitopes. Mol. Immunol. 33 (6), 485.
31. Rager-Zisman, B., Egan, J.E., Kress, Y., Bloom, B.R., 1984. Isolation of cold-sensitive mutants of measles virus from persistently infected murine neuroblastoma cells. J. Virol. 51, 845.
32. Redding, T.W., Schally, A.V., Tice, T.R., Meyers, W.E., 1984. Long acting delivery systems for peptides:Inhibition of rat prostate tumors by controlled release of D-Trp 6-LH-RH from injectable microparticles. Proc. Natl. Acad. Sci. USA 81, 5845.
33. Reddy, R., Zhou, F., Nair, S., Huang, L., Rouse, B.T., 1992. In vivo cytotoxic T lymphocyte induction with soluble proteins administered in liposomes. J. Immunol. 148, 1585.
34. Romero, P., Maryanski, J.L., Cordey, A.-S., Corradin, G., Nussenzweig, R.S., Zavala, F., 1989. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature 341, 323.
35. Rotzschke, O., Falk, K., Deres, H., Schild, H., Norda, M., Metzger, J., Jung, G., Rammensee, H.-G., 1990. Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature 348, 252.
36. Shirai, M., Pendleton, D.C., Ahlers, J., Takeshita, T., Newman, M., Berzofsky, J.A., 1994. Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs. J. Immunol. 152, 549.
37. Tabata, Y., Ikada, Y., 1990. Phagocytosis of polymer microspheres by macrophages. Adv. Polym. Sci. 94, 107.
38. Valitutti, S., Muller, S., Dessing, M., Lanzavecchia, A., 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183, 1917.
39. Verrechia, T., Huve, P., Bazile, D., Veillard, M., Spenlehauer, G., Couvreur, P., 1993. Adsorption/desorption of human serum albumin at the surface of poly(lactic acid) nanoparticles prepared by a solvent evaporation process. J. Biomed. Mater. Res. 27, 1019.