Analysis of the role of MHC class II presentation in the stimulation of cytotoxic T lymphocytes by antigens targeted into the exogenous antigen-MHC class I presentation pathway

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 3721-3726

  Rock, Kenneth L ^a,b   Clark, Karen ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CELL INTERACTION; CELLULAR IMMUNODEFICIENCY; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN PRESENTATION; CD4-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSPHERES; OVALBUMIN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0029887715     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Germain, R. N., and D. H. Margulies. 1993. The biochemistry and cell biology of antigen processing and presentation Annu. Rev Immunol. 11:403
2. York, I., and K. L. Rock. Antigen processing and presentation by the class I major histocompatibility complex Annu. Rev. Immunol. In press
3. Rock, K. L. 1996. A new foreign policy; MHC class I molecules monitor the outside world. Immunol. Today. 17:131.
4. Rock, K L., S. Gamble, and L. Rothstein. 1990. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science 249:918
5. Grant, E. P., and K. L. Rock. 1992. MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo. J. Immunol. 148:13
6. Kovacsovics-Bankowski, M., K. Clark, B. Benacerraf, and K. L. Rock 1993. Efficient MHC class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl. Acad. Sci. USA 90:4942.
7. Harding, C. V , and R. Song. 1994. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J. Immunol. 153:4925.
8. Kovacsovics-Bankowski, M., and K. L. Rock. 1995. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 267:243.
9. Reis e Sousa, C., and R. N. Germain. 1995. Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 182:841.
10. Pfeifer, J D., M J. Wick, R. L. Roberts, K. Fidlay, S. J Normark, and C V. Harding. 1993. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells Nature. 361:359.
11. Bachmann, M F., A. Oxenius, H. Pircher, H. Hengartner, P. Ashton-Richardt, S. Tonegawa, and R M Zinkernagel. 1995. TAP1-independent loading of class I molecules by exogenous viral proteins. Eur. J. Immunol. 25:1739.
12. Romero, P., J. L. Maryanski, G. Corradin, R S Nussenzweig, V. Nussenzweig, and F. Zavala. 1989. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature. 341:323.
13. Kaleab, B., T. Ottenoff, P. Converse, E. Halapi, G. Tadesse, M. Rottenberg, and R. Kiessling. 1990. Mycobacteria-induced cytotoxic T cells as well as nonspecific killer cells derived from healthy individuals and leprosy patients. Eur. J. Immunol. 20.2651
14. Flynn, J. L., M. M Goldstein, K. J. Triebold, B. Koller, and B. R. Bloom. 1992. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA. 89:12013.
15. + cytotoxic T cell. Eur. J. Immunol. 24:2813.
16. Bevan, M J. 1976. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp Med. 143:1283
17. Goading, L. R., and C B Edwards 1980 H-2 antigen requirements in the in vitro induction of SV40-speciflc cytotoxic T lymphocytes J. Immunol. 124.1258.
18. Huang, A., P. Golumbek. M Ahmadzadeh, E Jaffee, D Pardoll, and H. Levitsky. 1994. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 264:961
19. Kovacsovics-Bankowski, M., and K. Rock. 1994. Presentation of exogenous antigens by macrophages: analysis of major histocompatibility complex class I and II presentation and regulation by cytokines. Eur. J. Immunol. 24 2421.
20. Falo, L D., Jr., M. Kovacsovics-Bankowski, K. Thompson, and K. L. Rock. 1995. Vaccination with particulate antigen induces protective tumor immunity. Nat. Med. 1:649.
21. Ashman, R , and A Mullbacher. 1979 A helper cell for antiviral cytotoxic T cell responses. J. Exp. Med. 150:1277.
22. von Boehmer, H., and W Haas. 1979. Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen. J. Exp. Med. 150:1134
23. Keene, J , and J Forman. 1982. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med 155:768
24. Plate, J. 1976 Soluble factors substitute for T-T-cell collaboration in generation of T-killer lymphocytes. Nature. 260:329.
25. Wagner, H., C. Hardt, K Heeg, K. Pfizenmater, W. Solbach, R. Bartlett, H Stockinger, and M Rollinghoff. 1980. T-T cell interactions during cytotoxic T lymphocyte (CTL) responses: T cell derived helper factor (Interleukin 2) as a probe to analyze CTL responsiveness and thymic maturation of CTL progenitors. Immunol. Rev. 51.215.
26. Mitchison, N., and C. O'Malley. 1987 Three-cell-type clusters of T cells with antigen-presenting cells best explain the epitope linkage and noncognate requirements of the in vivo cytolytic response. Eur. J. Immunol. 17.1579.
27. + T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system. J. Gen. Virol. 68:825.
28. Buller, R., K Holmes, A. Hugin, T Frederickson, and H. C Morse, III. 1987. Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells. Nature. 328.77.
29. + T helper cell function in vivo, differential requirement for induction of antiviral cytotoxic T-cell and antibody responses. J. Virol 62.2102.
30. Bodmer, H , G. Obert, S. Chan, C. Benoist, and D Mathis 1993. Environmental modulation of the autonomy of cytotoxic T lymphocytes. Eur. J Immunol 23: 1649
31. + T cells in major histocompatibility complex class II-deficient mice. Science 253:1417.
32. Gorer, P., and D Amos. 1956. Passive immunity in mice against C57GL leukosis EL4 by means of iso-immune sera Cancer Res 16 338
33. Moore, M. W., F. R. Carbone, and M. J Bevan 1988 Introduction of soluble protein into the class I pathway of antigen processing and presentation Cell 54:777.
34. Bhattacharya, A., M. Dorf, and T. Springer 1981 A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions evidence for I region gene duplication. J Immunol. 127 2488
35. Stallcup, K., T. A. Springer, and M. F. Mescher 1981 Characterization of an anti-H-2 monoclonal antibody and its use in large scale antigen purification J. Immunol. 127:923
36. Davignon, D , E. Martz, T Reynolds, K. Kurzinger, and T Springer. 1981. Lymphocyte function-associated antigen 1 (LFA-1) a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing. Proc. Natl Acad Sci USA. 78 4535.
37. Raulet, D., P. Gottlieb, and M. Bevan. 1980 Fractionation of lymphocyte populations with monoclonal antibodies specific for LYT-2.2 and LYT-3 1. J. Immunol. 125:1136.
38. Dialynas, D., D. Wilde, P. Marrack, A Pierres, K Wall, W Havran, G Otten, M. Loken, M. Pierres, J. Kappler, and F. Fitch 1983 Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol. Rev 74:29
39. Rock, K. L., L. Rothstein, and S. Gamble. 1990. Generation of class I MHC-restricted T-T hybridomas. J. Immunol. 145:804
40. Coligan, J. E. 1992 Current Protocols in Immunology Green Publishing, Wiley Interscience.
41. Rock, K. L., and B. Benacerraf. 1983. Inhibition of antigen-specific T lymphocyte activation by structurally related Ir gene controlled polymers: evidence of specific competition for accessory cell antigen-presentation J Exp. Med. 157: 1618
42. + T cell responses by antigens covalentiy linked to synthetic microspheres does not require adjuvant. Int. Immunol. 7:45.
43. Gosgrove, D., D. Gray, A. Dierich, J. Kaufman, M. Lemeur, C Benoist, and D. Mathis. 1991. Mice lacking MHC class II molecules. Cell 66 1051.
44. + cells in mediating skin graft rejection against different amounts of transgenic H-2K(b) antigen J Exp Med. 173:261
45. + T cells try B7-transfected melanoma cells Science. 259:368.
46. + T-cell responses. Current Biology, 4 499
47. + helper cell requirement in cytotoxic T lymphocyte responses Eur J Immunol. 18 219.
48. Mosmann, T., and R Coffman 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7 145
49. Mitchison, N 1990. An exact comparison between the efficiency of two- and three-cell-type clusters in mediating helper activity. Eur. J. Immunol. 20:699.
50. Guerder, S., and P Matzinger. 1992 A fail-safe mechanism for maintaining self-tolerance J Exp. Med. 176.533
51. Kundig, T. M , M F Bachmann, C. DiPaolo, J. I. L. Simard, M Battegay, H Lother, A. Gessner, K. Kuhlcke, P S. Ohashi, H Hengartner, and R. M. Zinkernagel 1995 Fibroblasts as efficient antigen-presenting cells in lymphoid organs Science. 268:1343
52. Lafferty, K J., S. J Prowse, C. J. Simeonovic, and H S. Warren. 1983. Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Annu. Rev Immunol. 1:143
53. Ohashi, P. S., S Oehen, K. Buerki, H. Pircher, C. T. Ohashi, B. Odermatt, B. Malissen, R M Zinkernagel, and H. Hengartner. 1991. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice Cell 65:305.
54. Chen, L , S Ashe, W A. Brady, I. Hellstrom, K E. Hellstrom, J. A. Ledbetter, P. McGowan, and P S. Linsley. 1992 Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell. 71 1093.