A 3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro

British Journal of Pharmacology

Volumn 147, Issue 5, 2006, Pages 524-532

  Pugliese, Anna Maria ^a   Coppi, Elisabetta ^a   Spalluto, Giampiero ^b   Corradetti, Renato ^a   Pedata, Felicita ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

A 3 receptors; Adenosine; Anoxic depolarisation; Cerebral ischaemia; Hippocampal slices; Synaptic potential

Indexed keywords

3 PROPYL 6 ETHYL 5 [(ETHYLTHIO)CARBONYL] 2 PHENYL 4 PROPYL 3 PYRIDINECARBOXYLATE; 5 [[(4 PYRIDYL)AMINO]CARBONYL]AMINO 8 METHYL 2 (2 FURYL)PYRAZOLO[4,3 E] 1,2,4 TRIAZOLO[1,5C]PYRIMIDINE; 6 ETHYL 4 PROPYL 2 PHENYL 3 PYRIDINECARBOXYLIC ACID 5 THIOCARBOXYLIC ACID 5 ETHYL 3 PROPYL ESTER; 9 CHLORO 2 (2 FURYL) 5 PHENYLACETYLAMINO 1,2,4 TRIAZOLO[1,5 C]QUINAZOLINE; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR ANTAGONIST; GLUCOSE; N (2 METHOXYPHENYL) N' [2 (3 PYRINDINYL) 4 QUINAZOLINYL]UREA; OXYGEN; UNCLASSIFIED DRUG; VUF 5574; 2,3 DIETHYL 4,5 DIPROPYL 6 PHENYLPYRIDINE 3 THIOCARBOXYLATE 5 CARBOXYLATE; 2,3-DIETHYL-4,5-DIPROPYL-6-PHENYLPYRIDINE-3-THIOCARBOXYLATE-5-CARBOXYLATE; PYRIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL TISSUE; ANOXIA; ARTICLE; BRAIN ISCHEMIA; BRAIN REGION; BRAIN SLICE; CONTROLLED STUDY; DEPOLARIZATION; DRUG SELECTIVITY; EVOKED RESPONSE; HIPPOCAMPUS; HYPOXIA; IN VITRO STUDY; MALE; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECORDING; SYNAPSE; TIME; TISSUE SLICE; ACTION POTENTIAL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; HYPOGLYCEMIA; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPTIC TRANSMISSION; WISTAR RAT;

ACTION POTENTIALS; ANIMALS; ANOXIA; BRAIN ISCHEMIA; HIPPOCAMPUS; HYPOGLYCEMIA; MALE; PYRIDINES; QUINAZOLINES; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A3; SYNAPTIC TRANSMISSION; TIME FACTORS; TRIAZOLES;

EID: 33644818481     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706646     Document Type: Article

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