Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages

Environmental Health Perspectives

Volumn 109, Issue SUPPL. 4, 2001, Pages 613-618

  Beck Speier, Ingrid ^a   Dayal, Niru ^a   Karg, Erwin ^a   Maier, Konrad L ^a   Roth, Christa ^a   Ziesenis, Axel ^a   Heyder, Joachim ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

5 lipoxygenase; Alveolar macrophages; Cyclooxygenase; Leukotrienes; Phospholipase A2; Prostaglandis; Ultrafine particles

Indexed keywords

ARACHIDONIC ACID; CARBON; LEUKOTRIENE B4; LIPID; LIPOXYGENASE; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; THROMBOXANE B2; TITANIUM DIOXIDE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOG; DOWN REGULATION; ENZYME ACTIVATION; EVALUATION; HYPOTHESIS; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INCUBATION TIME; INFLAMMATION; LEUKOCYTE ACTIVATION; LUNG ALVEOLUS MACROPHAGE; MEDIATOR RELEASE; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PHYSICAL DISEASE; PRIORITY JOURNAL; RESPIRATORY BURST; SUPERNATANT; SURFACE PROPERTY;

ANIMALIA; CANIS FAMILIARIS; SIGANUS;

EID: 0034837427     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109s4613     Document Type: Article

References (38)

1. Acute respiratory effects of particulate air pollution
2. Particulate air pollution and acute health effects
3. Association of particulate air pollution and acute mortality: Involvement of ultrafine particles?
4. Respiratory effects are associated with the number of ultrafine particles
5. Role of the alveolar macrophage in lung injury: Studies with ultrafine particles
6. Factors that influence the suppression of pulmonary antibacterial defenses in mice exposed to ozone
7. Modulation of human alveolar macrophage properties by ozone exposure in vitro
8. Pro-inflammatory response of alveolar macrophages induced by sulphite: Studies with lucigenin-dependent chemiluminescence
9. Sulfite induces release of lipid mediators by alveolar macrophages
10. 2 from macrophages of rats with silicosis
11. Modulation of eicosanoid production by human alveolar macrophages exposed to silica in vitro
12. Induction of prostaglandin H synthase 2 in human airway epithelial cells exposed to residual oil fly ash
13. Differential responsiveness of human neutrophils to the autocrine actions of 1-O-alkyl-homologs and 1-acyl analogs of platelet activating factor
14. Enhancement of human neutrophil responses to platelet activating factor by 5(S)-hydroxy-eicosatetraenoate
15. Biology and pathophysiology of leukotrienes
16. Arachidonic acid metabolites regulate interleukin-1 production
17. 2
18. Prostaglandins affect the respiratory burst of human neutrophils
19. Review article: New insights into prostaglandins and mucosal defense
20. Do inhaled ultrafine particles cause acute health effects in rats? I: Particle production
21. Early responses of the canine respiratory tract following long-term exposure to a sulfur(IV) aerosol at low concentrations. II: Biochemistry and cell biology of lung lavage fluid
22. Directed shift of fatty acids from phospholipids to triacylglycerols in HL-60 cells induced by nanomolar concentrations of triethyl lead chloride: Involvement of a pertussis toxin-sensitive pathway
23. Inhibition by pesticides of prostaglandin formation in blood platelets
24. Phagocytic leukocyte oxygenation activities and chemiluminescence: A kinetic approach to analysis
25. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems
26. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in baculovirus system
27. Effects of leukotrienes and f-Met-Leu-Phe on oxidative metabolism of neutrophils and eosinophils
28. Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosin monophosphate
29. 2 regulates macrophage-derived tumor necrosis factor gene expression
30. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF
31. Role of IL-10 in the crossregulation of prostaglandins and cytokines in monocytes
32. The effects of different silicas on arachidonic acid metabolism in alveolar macrophages
33. Inflammatory and fibrotic mediator release by alveolar macrophages from coal miners
34. Influence of mineral dust surface chemistry on eicosanoid production by the alveolar macrophage
35. 2 particles in-vitro
36. Effect of oxidative stress on receptors and signal transmission