Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor δ gene are associated with skeletal muscle glucose uptake

Diabetes

Volumn 54, Issue 12, 2005, Pages 3587-3591

  Vänttinen, Markku ^a   Nuutila, Pirjo ^b   Kuulasmaa, Teemu ^a   Pihlajamäki, Jussi ^a   Hällsten, Kirsti ^b   Virtanen, Kirsi A ^b   Lautamäki, Riikka ^b   Peltoniemi, Pauliina ^b   Takala, Teemu ^b   Viljanen, Antti P M ^b   Knuuti, Juhani ^b   Laakso, Markku ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA;

ADIPOSE TISSUE; ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MAPPING; GENOTYPE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TRANSPORT; HAPLOTYPE; HUMAN; HUMAN TISSUE; INSULIN SENSITIVITY; MALE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE;

ADIPOSE TISSUE; ADULT; BIOLOGICAL TRANSPORT; CHROMOSOME MAPPING; FEMALE; GLUCOSE; HUMANS; INSULIN; MALE; MUSCLE, SKELETAL; POLYMORPHISM, SINGLE NUCLEOTIDE; PPAR DELTA;

EID: 33644688988     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/diabetes.54.12.3587     Document Type: Article

References (24)

1. Evans RM, Barish GD, Wang YX: PPARs and the complex journey to obesity. Nat Med 10:355-361, 2004
2. Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM: Peroxisome-proliferator-activated receptor d activates fat metabolism to prevent obesity. Cell 113:159-170, 2003
3. Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J: Activation of peroxisome proliferator-activated receptor d induces fatty acid b-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci U S A 100:15924-15929, 2003
4. Amri E-Z, Bonino F, Ailhaud G, Abumrad NA, Grimaldi PA: Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. J Biol Chem 270:2367-2371, 1995
5. Leibowitz MD, Fievet C, Hennuyer N, Peinado-Onsurbe J, Duez H, Bergera J, Cullinan CA, Sparrow CP, Baffic J, Berger GD, Santini C, Marquis RW, Tolman RL, Smith RG, Moller DE, Auwerx J: Activation of PPARdelta alters lipid metabolism in db/db mice. FEBS Lett 473:333-336, 2000
6. Oliver WR Jr, Shenk JL, Snaith MR, Russell CS, Plunket KD, Bodkin NL, Lewis MC, Winegar DA, Sznaidman ML, Lambert MH, Xu HE, Sternbach DD, Kliewer SA, Hansen BC, Willson TM: A selective peroxisome proliferator-activated receptor d agonist promotes reverse cholesterol transport. Proc Natl Acad Sci U S A 98:5306-5311, 2001
7. Dressel U, Allen TL, Pippal JB, Rohde PR, Lau P, Muscat GEO: The peroxisome proliferator-activated receptor b/d agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Mol Endocrinol 17:2477-2493, 2003
8. Yoshikawa T, Brkanac Z, Dupont BP, Xing GQ, Leach RJ, Detera-Wadleigh SD: Assigment of the human nuclear receptor, NUC1 (PPARD), to chromosome 6p21.1-p21.2. Genomics 35:637-638, 1996
9. Shin HD, Park BL, Kim LH, Jung HS, Cho YM, Moon MK, Park YJ, Lee HK, Park KS: Genetic polymorphisms in peroxisome proliferator-activated receptor d associated with obesity. Diabetes 53:847-851, 2004
10. Vänttinen M, Nuutila P, Pihlajamäki J, Hällsten K, Virtanen KA, Lautamäki R, Peltoniemi P, Kemppainen J, Takala T, Viljanen AP, Knuuti J, Laakso M: The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study. J Clin Endocrinol Metab 90:4249-4254, 2005
11. 18F]fluoro- deoxy-glucose and positron emission tomography. J Clin Invest 97:1741-1747, 1996
12. 18F]fluoro-deoxy- glucose, and positron emission tomography. Diabetes 49:1084-1091, 2000
13. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916, 1977
14. Patlak C, Blasberg R: Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data: generalizations. J Cereb Blood Flow Metab 5:584-590, 1985
15. 18F]FDG) and PET in combination with microdialysis. Diabetologia 44:2171-2179, 2001
16. 18F] fluorodeoxyglucose in skeletal muscles of obese and nonobese humans. Am J Physiol Endocrinol Metab 279:E1122-E1130, 2000
17. Kety S: Theory of blood-tissue exchange and its application to measurement of diffucible substance. Meth Med 8:223-227, 1960
18. Ruotsalainen U, Raitakari M, Nuutila P, Oikonen V, Sipila H, Teräs M, Knuuti MJ, Bloomfield P, Iida H: Quantitative blood flow measurement of skeletal muscle using oxygen-15-water and PET. J Nucl Med 38:314-319, 1997
19. Friedewald W, Levy R, Fredrickson D: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502, 1972
20. The International HapMap Consortium: The International HapMap Project. Nature 426:789-796, 2003
21. Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265, 2005
22. Grimaldi PA: Regulatory role of peroxisome proliferator-activated receptor delta (PPARδ) in muscle metabolism: a new target for metabolic syndrome treatment? Biochemie 87:5-8, 2005
23. Wang YX, Zhang C-L, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM: Regulation of muscle fiber type and runing endurance by PPARδ. PLOS Biol 10:e294, 2004
24. Krämer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, Kannisto K, Wallenberg-Henriksson H, Ehrenborg E, Zierath JR, Krook A: Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor δ. Diabetes 54:1157-1163, 2005