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Volumn 18, Issue 3, 2006, Pages 435-444

Antigen dose governs the shaping of CTL repertoires in vitro and in vivo

Author keywords

Antigen dos; CTL; Repertoire development; T cell avidity

Indexed keywords

T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 33644668499     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxh383     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 0032080641 scopus 로고    scopus 로고
    • MHC class I/peptide stability: Implications for immunodominance, in vitro proliferation, and diversity of responding CTL
    • Busch, D. H. and Pamer, E. G. 1998. MHC class I/peptide stability: implications for immunodominance, in vitro proliferation, and diversity of responding CTL. J. Immunol. 160:4441.
    • (1998) J. Immunol. , vol.160 , pp. 4441
    • Busch, D.H.1    Pamer, E.G.2
  • 2
    • 0034252309 scopus 로고    scopus 로고
    • Epitope affinity for MHC class I determines helper requirement for CTL priming
    • Franco, A., Tilly, D. A., Gramaglia, I. et al. 2000. Epitope affinity for MHC class I determines helper requirement for CTL priming. Nat. Immunol. 1:145.
    • (2000) Nat. Immunol. , vol.1 , pp. 145
    • Franco, A.1    Tilly, D.A.2    Gramaglia, I.3
  • 3
    • 0031766182 scopus 로고    scopus 로고
    • The organization of mature T-cell pools
    • Tanchot, C. and Rocha, B. 1998. The organization of mature T-cell pools. Immunol. Today 19:575.
    • (1998) Immunol. Today , vol.19 , pp. 575
    • Tanchot, C.1    Rocha, B.2
  • 4
    • 0032143604 scopus 로고    scopus 로고
    • Individual variations in the murine Tcell response to a specific peptide reflect variability in naive repertoires
    • Bousso, P., Casrouge, A., Altman, J. D. et al. 1998. Individual variations in the murine Tcell response to a specific peptide reflect variability in naive repertoires. Immunity 9:169.
    • (1998) Immunity , vol.9 , pp. 169
    • Bousso, P.1    Casrouge, A.2    Altman, J.D.3
  • 5
    • 0035854484 scopus 로고    scopus 로고
    • Regulation of the immune response by antigen
    • Zinkernagel, R. M. and Hengartner, H. 2001. Regulation of the immune response by antigen. Science 293:251.
    • (2001) Science , vol.293 , pp. 251
    • Zinkernagel, R.M.1    Hengartner, H.2
  • 6
    • 0033578388 scopus 로고    scopus 로고
    • An inverse relationship between T cell receptor affinity and antigen dose during CD4+ T cell responses in vivo and in vitro
    • Rees, W., Bender, J., Teague, T. K. et al. 1999. An inverse relationship between T cell receptor affinity and antigen dose during CD4+ T cell responses in vivo and in vitro. Proc. Natl Acad. Sci. USA 96:9781.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9781
    • Rees, W.1    Bender, J.2    Teague, T.K.3
  • 7
    • 0033972234 scopus 로고    scopus 로고
    • Decrypting the spectrum of antigen-specific T-cell responses: The avidity repertoire of MBP-specific T-cells
    • Mazzanti, B., Hemmer, B., Traggiai, E. et al. 2000. Decrypting the spectrum of antigen-specific T-cell responses: The avidity repertoire of MBP-specific T-cells. J. Neurosci. Res. 59:86.
    • (2000) J. Neurosci. Res. , vol.59 , pp. 86
    • Mazzanti, B.1    Hemmer, B.2    Traggiai, E.3
  • 8
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller, M. A., Leggatt, G. R. and Berzofsky, J. A. 1996. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc. Natl Acad. Sci. USA 93:4102.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 4102
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 9
    • 0037307786 scopus 로고    scopus 로고
    • Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice
    • Chun, E.Y., Lee, J., Cheong, H. S. and Lee, K. Y. 2003. Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice. J. Immunol. 170:1183.
    • (2003) J. Immunol. , vol.170 , pp. 1183
    • Chun, E.Y.1    Lee, J.2    Cheong, H.S.3    Lee, K.Y.4
  • 10
    • 0033568203 scopus 로고    scopus 로고
    • Peptide affinity and concentration affect the sensitivity of M3-restricted CTLs induced in vitro
    • Byers, D. E. and Lindahl, K. F. 1999. Peptide affinity and concentration affect the sensitivity of M3-restricted CTLs induced in vitro. J. Immunol. 163:3022.
    • (1999) J. Immunol. , vol.163 , pp. 3022
    • Byers, D.E.1    Lindahl, K.F.2
  • 11
    • 0029813121 scopus 로고    scopus 로고
    • Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL
    • Alexander-Miller, M. A., Leggatt, G. R., Sarin, A. and Berzofsky, J. A. 1996. Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. J. Exp. Med. 184:485.
    • (1996) J. Exp. Med. , vol.184 , pp. 485
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Sarin, A.3    Berzofsky, J.A.4
  • 12
    • 0033532540 scopus 로고    scopus 로고
    • Evolution of antigen-specific Tcell receptors in vivo: Preimmune and antigen-driven selection of preferred CDR3 motifs
    • McHeyzer-Williams, L. J., Panus, J. F., Mikszta, J. A. and McHeyzer-Williams, M. G. 1999. Evolution of antigen-specific Tcell receptors in vivo: Preimmune and antigen-driven selection of preferred CDR3 motifs. J. Exp. Med. 189:1823.
    • (1999) J. Exp. Med. , vol.189 , pp. 1823
    • McHeyzer-Williams, L.J.1    Panus, J.F.2    Mikszta, J.A.3    McHeyzer-Williams, M.G.4
  • 13
    • 0033118739 scopus 로고    scopus 로고
    • A kinetic basis for T cell receptor repertoire selection during an immune response
    • Savage, P. A., Boniface, J. J. and Davis, M. M. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 10:485.
    • (1999) Immunity , vol.10 , pp. 485
    • Savage, P.A.1    Boniface, J.J.2    Davis, M.M.3
  • 14
    • 0034675848 scopus 로고    scopus 로고
    • T cells compete for access to antigen-bearing antigen-presenting cells
    • Kedl, R. M., Rees, W. A., Hildeman, D. A. et al. 2000. T cells compete for access to antigen-bearing antigen-presenting cells. J. Exp. Med. 192:1105.
    • (2000) J. Exp. Med. , vol.192 , pp. 1105
    • Kedl, R.M.1    Rees, W.A.2    Hildeman, D.A.3
  • 15
    • 0032211137 scopus 로고    scopus 로고
    • Immunodominance in the CTL response against minor histocompatibility antigen: Interference between responding T cells, rather than with presentation of epitopes
    • Wolpert, E. Z., Grufman, P., Sandberg, J. K., Tegnesjo, A. and Karre, K. 1998. Immunodominance in the CTL response against minor histocompatibility antigen: Interference between responding T cells, rather than with presentation of epitopes. J. Immunol. 161:4499.
    • (1998) J. Immunol. , vol.161 , pp. 4499
    • Wolpert, E.Z.1    Grufman, P.2    Sandberg, J.K.3    Tegnesjo, A.4    Karre, K.5
  • 16
    • 0033557173 scopus 로고    scopus 로고
    • T cell affinity maturation by selective expansion during infection
    • Busch, D. H. and Pamer, E. G. 1999. T cell affinity maturation by selective expansion during infection. J. Exp. Med. 189:701.
    • (1999) J. Exp. Med. , vol.189 , pp. 701
    • Busch, D.H.1    Pamer, E.G.2
  • 17
    • 0024852851 scopus 로고
    • Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor
    • Duerksen-Huges, P., Wold, L. W. M. and Gooding, L. R. 1989. Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor. J. Immunol. 143:4193.
    • (1989) J. Immunol. , vol.143 , pp. 4193
    • Duerksen-Huges, P.1    Wold, L.W.M.2    Gooding, L.R.3
  • 19
    • 0036061535 scopus 로고    scopus 로고
    • + T cell responses against a single epitope of adenovirus E1B
    • + T cell responses against a single epitope of adenovirus E1B. Virology 295:238.
    • (2002) Virology , vol.295 , pp. 238
    • Kim, M.1    Kim, K.2
  • 20
    • 0034677055 scopus 로고    scopus 로고
    • Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
    • Daniels, M. A. and Jameson, S. C. 2000. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers. J. Exp. Med. 191:335.
    • (2000) J. Exp. Med. , vol.191 , pp. 335
    • Daniels, M.A.1    Jameson, S.C.2
  • 21
    • 0033082128 scopus 로고    scopus 로고
    • T cell receptor and coreceptor CD8αα bind peptide-MHC independently and with distinct kinetics
    • Wyer, J. R., Willcox, B. E., Gao, G. F. et al. 1999. T cell receptor and coreceptor CD8αα bind peptide-MHC independently and with distinct kinetics. Immunity 10:210.
    • (1999) Immunity , vol.10 , pp. 210
    • Wyer, J.R.1    Willcox, B.E.2    Gao, G.F.3
  • 22
    • 0029807351 scopus 로고    scopus 로고
    • CD8 enhances formation of stable T cell receptor/MHC class I molecule complexes
    • Garcia, K. C., Scott, C. A., Brunmark, A. et al. 1996. CD8 enhances formation of stable T cell receptor/MHC class I molecule complexes. Nature 384:577.
    • (1996) Nature , vol.384 , pp. 577
    • Garcia, K.C.1    Scott, C.A.2    Brunmark, A.3
  • 23
    • 0025805695 scopus 로고
    • Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes
    • Alexander, M. A., Damico, C. A., Wieties, K. M., Hansen, T. H. and Connolly, J. M. 1991. Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes. J. Exp. Med. 173:849.
    • (1991) J. Exp. Med. , vol.173 , pp. 849
    • Alexander, M.A.1    Damico, C.A.2    Wieties, K.M.3    Hansen, T.H.4    Connolly, J.M.5
  • 24
    • 0028215537 scopus 로고
    • T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis
    • Critchfield, J. M., Racke, M. K., Zuniga-Pflucker, J. C. et al. 1994. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 263:1139.
    • (1994) Science , vol.263 , pp. 1139
    • Critchfield, J.M.1    Racke, M.K.2    Zuniga-Pflucker, J.C.3
  • 25
    • 0029935569 scopus 로고    scopus 로고
    • Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors
    • Toes, R. E., Blom, R. J., Offringa, R., Kast, W. M. and Melief, C. J. 1996. Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors. J. Immunol. 156:3911.
    • (1996) J. Immunol. , vol.156 , pp. 3911
    • Toes, R.E.1    Blom, R.J.2    Offringa, R.3    Kast, W.M.4    Melief, C.J.5
  • 26
    • 0025791952 scopus 로고
    • T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: Implications for T cell allelic exclusion and antigen-specific repertoire
    • Casanova, J. L., Romero, P., Widmann, P., Kourilsky, P. and Maryanski, J. L. 1991. T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: Implications for T cell allelic exclusion and antigen-specific repertoire. J. Exp. Med. 174:1371.
    • (1991) J. Exp. Med. , vol.174 , pp. 1371
    • Casanova, J.L.1    Romero, P.2    Widmann, P.3    Kourilsky, P.4    Maryanski, J.L.5
  • 27
    • 0028085101 scopus 로고
    • T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity
    • Horwitz, M. S., Yanagi, Y. and Oldstone, M. B. 1994. T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity. J. Virol. 68:352.
    • (1994) J. Virol. , vol.68 , pp. 352
    • Horwitz, M.S.1    Yanagi, Y.2    Oldstone, M.B.3
  • 28
    • 0032400941 scopus 로고    scopus 로고
    • Polyclonality and multispecificity of the CTL response to a single viral epitope
    • Ishikawa, T., Kono, D., Chung, J. et al. 1998. Polyclonality and multispecificity of the CTL response to a single viral epitope. J. Immunol. 161:5842.
    • (1998) J. Immunol. , vol.161 , pp. 5842
    • Ishikawa, T.1    Kono, D.2    Chung, J.3
  • 29
    • 0027163489 scopus 로고
    • b-restricted response to an influenza A virus nucleoprotein epitope
    • b-restricted response to an influenza A virus nucleoprotein epitope. J. Immunol. 151:2658.
    • (1993) J. Immunol. , vol.151 , pp. 2658
    • Deckhut, A.M.1    Allan, W.2    McMickle, A.3
  • 30
    • 0029087314 scopus 로고
    • Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias
    • Cose, S. C., Kelly, J. M. and Carbone, F. R. 1995. Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias. J. Virol. 69:5849.
    • (1995) J. Virol. , vol.69 , pp. 5849
    • Cose, S.C.1    Kelly, J.M.2    Carbone, F.R.3
  • 31
    • 0032490673 scopus 로고    scopus 로고
    • Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection
    • Busch, D. H., Pilip, I. and Pamer, E. G. 1998. Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection. J. Exp. Med. 188:61.
    • (1998) J. Exp. Med. , vol.188 , pp. 61
    • Busch, D.H.1    Pilip, I.2    Pamer, E.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.