Convenient asymmetric synthesis of β-trifluoromethyl-β-amino acid, β-amino ketones, and γ-amino alcohols via Reformatsky and Mannich-type reactions from 2-trifluoromethyl-1,3-oxazolidines

Journal of Organic Chemistry

Volumn 71, Issue 5, 2006, Pages 2159-2162

  Huguenot, Florent ^a   Brigaud, Thierry ^b  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b Université Paris Seine   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MANNICH-TYPE REACTION;

ALCOHOLS; KETONES; REACTION KINETICS; SYNTHESIS (CHEMICAL);

AMINO ACIDS;

2 TRIFLUOROMETHYL 1,3 OXAZOLIDINE; ACETALDEHYDE; AMINOALCOHOL; AMINOKETONE; BETA AMINO ACID; BETA AMINOKETONE; BETA TRIFLUOROMETHYL BETA AMINO ACID; CYCLOHEXANONE DERIVATIVE; FLUORINE; GAMMA AMINOALCOHOL; IMINE; OXAZOLIDINE DERIVATIVE; PHENYLGLYCINE; TETRAHYDROFURAN; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; DIASTEREOISOMER; ENANTIOMER; MANNICH REACTION; REFORMATSKY REACTION; STEREOCHEMISTRY;

AMINO ACIDS; AMINO ALCOHOLS; KETONES; OXAZOLES; STEREOISOMERISM;

EID: 33644650296     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo052323p     Document Type: Article

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