Facile synthesis of trifluoromethyl carbinols and trifluoromethyl- α,β-unsaturated ketones from the new CF3CHO synthetic equivalent, 1,1- bis(dimethylamino)-2,2,2-trifluoroethane

Tetrahedron Letters

Volumn 39, Issue 50, 1998, Pages 9151-9154

  Xu, Yuelian ^a   Dolbier Jr , William R ^a  

^a University of Florida ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(DIMETHYLAMINO) 2,2,2 TRIFLUOROETHANE; ETHANE; KETONE DERIVATIVE; METHANOL DERIVATIVE; TRIFLUOROMETHYLCARBINOL; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; CHROMATOGRAPHY; DIASTEREOISOMER; ISOMER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERIZATION; REACTION ANALYSIS; SYNTHESIS;

EID: 0032506573     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02106-6     Document Type: Article

References (14)

1. [1] Filler R, Kobayashi Y, Yagupolskii LM, editors. Organofluorine compounds in medicinal chemistry and biomedical applications. Amsterdam:Elsevier,1993.
2. [2] McClinton MA, McClinton DA. Tetrahedron 1992;48:6555-6666.
3. [3] Kiehlmann E, Menon BC, McGillivray N. Can. J. Chem. 1973;51:3177-3188.
4. [4] Watanabe S, Sakai Y, Kitazume T, Yamazaki T. J. Fluorine Chem. 1994;68:59-61.
5. [5] Kitazume T, Lin JT, Yamazaki T. Tetrahedron Asym. 1991;2:235-238.
6. [6] Norcross BE, Klinedinst PEJr, Westheimer FH. J. Am. Chem. Soc. 1962;84:797-802.
7. [7] Loh T-P, Li X-R. Chem. Commun. 1996:1929-1930.
8. [8] Kubota T, Iijima M, Tanaka T. Tetrahedron Lett. 1992;33:1351-1354.
9. [9] Guy A, Lobgeois A, Lemaire M. J. Fluorine Chem. 1986;32:361-366.
10. [10] Imperiali B, Abeles RH. Tetrahedron Lett. 1986;27:135-138.
11. [11] Uneyama K, Momota M, Hayashida K, Itoh T. J. Org. Chem. 1990;55:5364-5368.
12. [12] Fuchigami T, Ichikawa S, Konno A. Chem. Lett. 1989:1987-1988.
13. [13] Fuchigami T, Ichikawa S. J. Org. Chem. 1994;59:607-615.
14. [14] Xu Y, Dolbier WRJr, Rong XX. J. Org. Chem. 1997;62:1576-1577.