메뉴 건너뛰기




Volumn 81, Issue 4, 2006, Pages 583-589

Tetrahydrobiopterin compounds prolong allograft survival independently of their effect on nitric oxide synthase activity

Author keywords

Immunosuppression; Murine cardiac allograft; Nitric oxide; Tetrahydrobiopterin

Indexed keywords

3 NITROTYROSINE; 4 AMINO TETRAHYDROBIOPTERIN; CD163 ANTIGEN; CD3 ANTIGEN; CHEMOKINE; CYCLOSPORIN A; CYTOKINE; GAMMA INTERFERON; GELATINASE A; GRANZYME B; IA ANTIGEN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 2 RECEPTOR BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; N6 (1 IMINOETHYL)LYSINE; NITRATE; NITRIC OXIDE SYNTHASE; NITRITE; PEROXYNITRITE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; T LYMPHOCYTE RECEPTOR BETA CHAIN; TETRAHYDROBIOPTERIN; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 33644615780     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000188949.03683.fd     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 10844244925 scopus 로고    scopus 로고
    • Drug therapy in the heart transplant recipient: Part I: Cardiac rejection and immunosuppressive drugs
    • Lindenfeld J, Miller GG, Shakar SF, et al. Drug therapy in the heart transplant recipient: part I: cardiac rejection and immunosuppressive drugs. Circulation 2004; 110: 3734.
    • (2004) Circulation , vol.110 , pp. 3734
    • Lindenfeld, J.1    Miller, G.G.2    Shakar, S.F.3
  • 2
    • 11144250154 scopus 로고    scopus 로고
    • Drug therapy in the heart transplant recipient: Part II: Immunosuppressive drugs
    • Lindenfeld J, Miller GG, Shakar SF, et al. Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs. Circulation 2004; 110: 3858.
    • (2004) Circulation , vol.110 , pp. 3858
    • Lindenfeld, J.1    Miller, G.G.2    Shakar, S.F.3
  • 3
    • 0037453062 scopus 로고    scopus 로고
    • Non-heme iron protein: A potential target of nitric oxide in acute cardiac allograft rejection
    • Pieper GM, Halligan NL, Hilton G, et al. Non-heme iron protein: a potential target of nitric oxide in acute cardiac allograft rejection. Proc Natl Acad Sci U S A 2003; 100: 3125.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 3125
    • Pieper, G.M.1    Halligan, N.L.2    Hilton, G.3
  • 4
    • 0028928647 scopus 로고
    • Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase
    • Worrall NK, Lazenby WD, Misko TP, et al. Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase. J Exp Med 1995; 181: 63.
    • (1995) J Exp Med , vol.181 , pp. 63
    • Worrall, N.K.1    Lazenby, W.D.2    Misko, T.P.3
  • 5
    • 0037304475 scopus 로고    scopus 로고
    • The cardioprotective and mitochondrial depolarising properties of exogenous nitric oxide in mouse heart
    • Bell RM, Maddock HL, Yellon DM. The cardioprotective and mitochondrial depolarising properties of exogenous nitric oxide in mouse heart. Cardiovasc Res 2003; 57: 405.
    • (2003) Cardiovasc Res , vol.57 , pp. 405
    • Bell, R.M.1    Maddock, H.L.2    Yellon, D.M.3
  • 6
    • 0032558159 scopus 로고    scopus 로고
    • Protective effect of ischemic preconditioning on liver preservation-reperfusion injury in rats
    • Yin DP, Sankary HN, Chong AS, et al. Protective effect of ischemic preconditioning on liver preservation-reperfusion injury in rats. Transplantation 1998; 66: 152.
    • (1998) Transplantation , vol.66 , pp. 152
    • Yin, D.P.1    Sankary, H.N.2    Chong, A.S.3
  • 7
    • 0030218114 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase attenuates established acute cardiac allograft rejection
    • Worrall NK, Misko TP, Sullivan PM, et al. Inhibition of inducible nitric oxide synthase attenuates established acute cardiac allograft rejection. Ann Thorac Surg 1996; 62: 378.
    • (1996) Ann Thorac Surg , vol.62 , pp. 378
    • Worrall, N.K.1    Misko, T.P.2    Sullivan, P.M.3
  • 8
    • 0028178810 scopus 로고
    • N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection
    • Bastian NR, Xu S, Shao XL, et al. N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection. Biochim Biophys Acta 1994; 1226: 225.
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 225
    • Bastian, N.R.1    Xu, S.2    Shao, X.L.3
  • 9
    • 0029858088 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition is associated with decreased survival of cardiac allografts in the rat
    • Paul LC, Myllarniemi M, Muzaffar S, Benediktsson H. Nitric oxide synthase inhibition is associated with decreased survival of cardiac allografts in the rat. Transplantation 1996; 62: 1193.
    • (1996) Transplantation , vol.62 , pp. 1193
    • Paul, L.C.1    Myllarniemi, M.2    Muzaffar, S.3    Benediktsson, H.4
  • 10
    • 0029827739 scopus 로고    scopus 로고
    • Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase
    • Werner ER, Pitters E, Schmidt K, et al. Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase. Biochem J 1996; 320(Pt 1): 193.
    • (1996) Biochem J , vol.320 , Issue.1 PART , pp. 193
    • Werner, E.R.1    Pitters, E.2    Schmidt, K.3
  • 11
    • 0033556220 scopus 로고    scopus 로고
    • Preferential inhibition of inducible nitric oxide synthase in intact cells by the 4-amino analogue of tetrahydrobiopterin
    • Schmidt K, Werner-Felmayer G, Mayer B, Werner ER. Preferential inhibition of inducible nitric oxide synthase in intact cells by the 4-amino analogue of tetrahydrobiopterin. Eur J Biochem 1999; 259: 25.
    • (1999) Eur J Biochem , vol.259 , pp. 25
    • Schmidt, K.1    Werner-Felmayer, G.2    Mayer, B.3    Werner, E.R.4
  • 12
    • 0034530631 scopus 로고    scopus 로고
    • Inhibition of endotoxin-induced vascular hyporeactivity by 4-amino-tetrahydrobiopterin
    • Gibraeil HD, Dittrich P, Saleh S, Mayer B. Inhibition of endotoxin-induced vascular hyporeactivity by 4-amino-tetrahydrobiopterin. Br J Pharmacol 2000; 131: 1757.
    • (2000) Br J Pharmacol , vol.131 , pp. 1757
    • Gibraeil, H.D.1    Dittrich, P.2    Saleh, S.3    Mayer, B.4
  • 13
    • 0034181284 scopus 로고    scopus 로고
    • Protection against endotoxemia in rats by a novel tetrahydrobiopterin analogue
    • Bahrami S, Fitzal F, Peichl G, et al. Protection against endotoxemia in rats by a novel tetrahydrobiopterin analogue. Shock 2000; 13: 386.
    • (2000) Shock , vol.13 , pp. 386
    • Bahrami, S.1    Fitzal, F.2    Peichl, G.3
  • 14
    • 0036689831 scopus 로고    scopus 로고
    • A 4-amino analogue of tetrahydrobiopterin attenuates endotoxin-induced hemodynamic alterations and organ injury in rats
    • Fitzal F, Redl H, Strohmaier W, et al. A 4-amino analogue of tetrahydrobiopterin attenuates endotoxin-induced hemodynamic alterations and organ injury in rats. Shock 2002; 18: 158.
    • (2002) Shock , vol.18 , pp. 158
    • Fitzal, F.1    Redl, H.2    Strohmaier, W.3
  • 15
    • 0034940593 scopus 로고    scopus 로고
    • The 4-amino analogue of tetrahydrobiopterin efficiently prolongs murine cardiac-allograft survival
    • Brandacher G, Zou Y, Obrist P, et al. The 4-amino analogue of tetrahydrobiopterin efficiently prolongs murine cardiac-allograft survival. J Heart Lung Transplant 2001; 20: 747.
    • (2001) J Heart Lung Transplant , vol.20 , pp. 747
    • Brandacher, G.1    Zou, Y.2    Obrist, P.3
  • 16
    • 0025828568 scopus 로고
    • Simplified mouse cervical heart transplantation using a cuff technique
    • Matsuura A, Abe T, Yasuura K. Simplified mouse cervical heart transplantation using a cuff technique. Transplantation 1991; 51: 896.
    • (1991) Transplantation , vol.51 , pp. 896
    • Matsuura, A.1    Abe, T.2    Yasuura, K.3
  • 17
    • 0025642851 scopus 로고
    • A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group
    • The International Society for Heart Transplantation
    • Billingham ME, Cary NR, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. The International Society for Heart Transplantation. J Heart Transplant 1990; 9: 587.
    • (1990) J Heart Transplant , vol.9 , pp. 587
    • Billingham, M.E.1    Cary, N.R.2    Hammond, M.E.3
  • 18
    • 0020448709 scopus 로고
    • Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
    • Green LC, Wagner DA, Glogowski J, et al. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982; 126: 131.
    • (1982) Anal Biochem , vol.126 , pp. 131
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 19
    • 13444304325 scopus 로고    scopus 로고
    • NCBI GEO: Mining millions of expression profiles-database and tools
    • Barrett T, Suzek TO, Troup DB, et al. NCBI GEO: mining millions of expression profiles-database and tools. Nucleic Acids Res 2005; 33: D562.
    • (2005) Nucleic Acids Res , vol.33
    • Barrett, T.1    Suzek, T.O.2    Troup, D.B.3
  • 20
    • 9044223657 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle
    • Lewis NP, Tsao PS, Rickenbacher PR, et al. Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle. Circulation 1996; 93: 720.
    • (1996) Circulation , vol.93 , pp. 720
    • Lewis, N.P.1    Tsao, P.S.2    Rickenbacher, P.R.3
  • 21
    • 0035933042 scopus 로고    scopus 로고
    • Acute cardiac allograft rejection in nitric oxide synthase-2(-/-) and nitric oxide synthase-2(+/+) mice: Effects of cellular chimeras on myocardial inflammation and cardiomyocyte damage and apoptosis
    • Szabolcs MJ, Ma N, Athan E, et al. Acute cardiac allograft rejection in nitric oxide synthase-2(-/-) and nitric oxide synthase-2(+/+) mice: effects of cellular chimeras on myocardial inflammation and cardiomyocyte damage and apoptosis. Circulation 2001; 103: 2514.
    • (2001) Circulation , vol.103 , pp. 2514
    • Szabolcs, M.J.1    Ma, N.2    Athan, E.3
  • 22
    • 0037195057 scopus 로고    scopus 로고
    • Effects of selective inhibitors of nitric oxide synthase-2 dimerization on acute cardiac allograft rejection
    • Szabolcs MJ, Sun J, Ma N, et al. Effects of selective inhibitors of nitric oxide synthase-2 dimerization on acute cardiac allograft rejection. Circulation 2002; 106: 2392.
    • (2002) Circulation , vol.106 , pp. 2392
    • Szabolcs, M.J.1    Sun, J.2    Ma, N.3
  • 23
    • 0032931313 scopus 로고    scopus 로고
    • Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis
    • Koglin J, Granville DJ, Glysing-Jensen T, et al. Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis. Circulation 1999; 99: 836.
    • (1999) Circulation , vol.99 , pp. 836
    • Koglin, J.1    Granville, D.J.2    Glysing-Jensen, T.3
  • 24
    • 19244374793 scopus 로고    scopus 로고
    • Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection
    • Pieper GM, Nilakantan V, Hilton G, et al. Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection. Am J Physiol Heart Circ Physiol 2004; 286: H525.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Pieper, G.M.1    Nilakantan, V.2    Hilton, G.3
  • 25
    • 0036636510 scopus 로고    scopus 로고
    • Anti-inflammatory effects of tetrahydrobiopterin on early rejection in renal allografts: Modulation of inducible nitric oxide synthase
    • Huisman A, Vos I, van Faassen EE, et al. Anti-inflammatory effects of tetrahydrobiopterin on early rejection in renal allografts: modulation of inducible nitric oxide synthase. FASEB J 2002; 16: 1135.
    • (2002) FASEB J , vol.16 , pp. 1135
    • Huisman, A.1    Vos, I.2    Van Faassen, E.E.3
  • 26
    • 0346848801 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and nitric oxide: Mechanistic and pharmacological aspects
    • Werner ER, Gorren AC, Heller R, et al. Tetrahydrobiopterin and nitric oxide: mechanistic and pharmacological aspects. Exp Biol Med (Maywood) 2003; 228: 1291.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 1291
    • Werner, E.R.1    Gorren, A.C.2    Heller, R.3
  • 27
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271: C1424.
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 28
    • 0033743985 scopus 로고    scopus 로고
    • Role of nitric oxide and superoxide in acute cardiac allograft rejection in rats
    • Akizuki E, Akaike T, Okamoto S, et al. Role of nitric oxide and superoxide in acute cardiac allograft rejection in rats. Proc Soc Exp Biol Med 2000; 225: 151.
    • (2000) Proc Soc Exp Biol Med , vol.225 , pp. 151
    • Akizuki, E.1    Akaike, T.2    Okamoto, S.3
  • 29
    • 0041465021 scopus 로고    scopus 로고
    • Microarray-based gene expression profiles of allogratt rejection and immunosuppression in the rat heart transplantation model
    • Erickson LM, Pan F, Ebbs A, et al. Microarray-based gene expression profiles of allogratt rejection and immunosuppression in the rat heart transplantation model. Transplantation 2003; 76: 582.
    • (2003) Transplantation , vol.76 , pp. 582
    • Erickson, L.M.1    Pan, F.2    Ebbs, A.3
  • 30
    • 0036644338 scopus 로고    scopus 로고
    • Analysis of the innate and adaptive phases of allograft rejection by cluster analysis of transcriptional profiles
    • Christopher K, Mueller TF, Ma C, et al. Analysis of the innate and adaptive phases of allograft rejection by cluster analysis of transcriptional profiles. J Immunol 2002; 169: 522.
    • (2002) J Immunol , vol.169 , pp. 522
    • Christopher, K.1    Mueller, T.F.2    Ma, C.3
  • 31
    • 0034909744 scopus 로고    scopus 로고
    • A comparison of gene expression in murine cardiac allografts and isografts by means DNA microarray analysis
    • Saiura A, Mataki C, Murakami T, et al. A comparison of gene expression in murine cardiac allografts and isografts by means DNA microarray analysis. Transplantation 2001; 72: 320.
    • (2001) Transplantation , vol.72 , pp. 320
    • Saiura, A.1    Mataki, C.2    Murakami, T.3
  • 33
    • 20444405032 scopus 로고    scopus 로고
    • Tetrahydro-4-aminobiopterin attenuates dendritic cell-induced T cell priming independently from inducible nitric oxide synthase
    • Thoeni G, Stoitzner P, Brandacher G, et al. Tetrahydro-4-aminobiopterin attenuates dendritic cell-induced T cell priming independently from inducible nitric oxide synthase. J Immunol 2005; 174: 7584.
    • (2005) J Immunol , vol.174 , pp. 7584
    • Thoeni, G.1    Stoitzner, P.2    Brandacher, G.3
  • 34
    • 0029128217 scopus 로고
    • Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion
    • Buerke M, Murohara T, Skurk C, et al. Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion. Proc Natl Acad Sci U S A 1995; 92: 8031.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8031
    • Buerke, M.1    Murohara, T.2    Skurk, C.3
  • 35
    • 0041344529 scopus 로고    scopus 로고
    • Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- Mice rescued by feeding neurotransmitter precursors and H4-biopterin
    • Elzaouk L, Leimbacher W, Turri M, et al. Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin. J Biol Chem 2003; 278: 28303.
    • (2003) J Biol Chem , vol.278 , pp. 28303
    • Elzaouk, L.1    Leimbacher, W.2    Turri, M.3
  • 36
    • 2542429299 scopus 로고    scopus 로고
    • The metabolic and molecular bases of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency
    • Blau N, Erlandsen H. The metabolic and molecular bases of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency. Mol Genet Metab 2004; 82: 101.
    • (2004) Mol Genet Metab , vol.82 , pp. 101
    • Blau, N.1    Erlandsen, H.2
  • 37
    • 13444262357 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: Regulator of endothelial nitric oxide synthase in vascular disease
    • Channon KM. Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 2004; 14: 323.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 323
    • Channon, K.M.1
  • 38
    • 17844386104 scopus 로고    scopus 로고
    • Tetrahydrobiopterin prevents cyclosporine-induced vasomotor dysfunction
    • Ramzy D, Rao V, Tumiati LC, et al. Tetrahydrobiopterin prevents cyclosporine-induced vasomotor dysfunction. Transplantation 2005; 79: 876.
    • (2005) Transplantation , vol.79 , pp. 876
    • Ramzy, D.1    Rao, V.2    Tumiati, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.