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Volumn 79, Issue 8, 2005, Pages 876-881

Tetrahydrobiopterin prevents cyclosporine-induced vasomotor dysfunction

Author keywords

Cyclosporine; Endothelial dysfunction; Endothelin 1; Nitric oxide; Tetrahydrobiopterin

Indexed keywords

ACETYLCHOLINE; CYCLOSPORIN A; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; NITRIC OXIDE; NITROPRUSSIDE SODIUM; SODIUM CHLORIDE; TETRAHYDROBIOPTERIN;

EID: 17844386104     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000157364.80712.45     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0024976004 scopus 로고
    • Cyclosporine
    • Kaham BD. Cyclosporine. N Eng J Med 1989; 321: 1725.
    • (1989) N Eng J Med , vol.321 , pp. 1725
    • Kaham, B.D.1
  • 2
    • 0035344771 scopus 로고    scopus 로고
    • Overview of side effects of immunosuppressive therapy
    • Paul LC. Overview of side effects of immunosuppressive therapy. Transpl Proc 2001; 33: 2089.
    • (2001) Transpl Proc , vol.33 , pp. 2089
    • Paul, L.C.1
  • 3
    • 0023201174 scopus 로고
    • Cardiac transplant atherosclerosis
    • Billingham ME. Cardiac transplant atherosclerosis. Transpl Proc 1987; 19: 19.
    • (1987) Transpl Proc , vol.19 , pp. 19
    • Billingham, M.E.1
  • 4
    • 0024976525 scopus 로고
    • Rapamycin for immunosuppression in organ allografting
    • Calne RY, Collier DSJ, Lim S, et al. Rapamycin for immunosuppression in organ allografting. Lancet 1989; 8656: 227.
    • (1989) Lancet , vol.8656 , pp. 227
    • Calne, R.Y.1    Collier, D.S.J.2    Lim, S.3
  • 5
    • 0026042403 scopus 로고
    • Effects of cyclosporin, FK506, and rapamycin on graft-vessel disease
    • Meiser BM, Billingham ME, Morris RE. Effects of cyclosporin, FK506, and rapamycin on graft-vessel disease. Lancet 1991; 339: 1297.
    • (1991) Lancet , vol.339 , pp. 1297
    • Meiser, B.M.1    Billingham, M.E.2    Morris, R.E.3
  • 6
    • 0023034071 scopus 로고
    • Cyclosporine-induced endothelial cell injury
    • Zoja C, Furci L, Ghilardi F, et al. Cyclosporine-induced endothelial cell injury. Lab Invest 1986; 55: 455.
    • (1986) Lab Invest , vol.55 , pp. 455
    • Zoja, C.1    Furci, L.2    Ghilardi, F.3
  • 7
    • 0034964069 scopus 로고    scopus 로고
    • Endothelial dysfunction, atherosclerosis and cyclosporine in renal transplantation
    • Paul LC. Endothelial dysfunction, atherosclerosis and cyclosporine in renal transplantation. Nether J Med 2001; 59: 1.
    • (2001) Nether J Med , vol.59 , pp. 1
    • Paul, L.C.1
  • 8
    • 0034254875 scopus 로고    scopus 로고
    • Does cyclosporine a generate free radicals?
    • Buetler TM, Cottet-Marie F, Krauskopf A, et al. Does cyclosporine A generate free radicals? TiPS 2000; 21: 288.
    • (2000) TiPS , vol.21 , pp. 288
    • Buetler, T.M.1    Cottet-Marie, F.2    Krauskopf, A.3
  • 9
    • 0033918552 scopus 로고    scopus 로고
    • Endothelial dysfunction in renal transplant recipients maintained with cyclosporine
    • Morris ST, McMurray JJ, Rodger SC, et al. Endothelial dysfunction in renal transplant recipients maintained with cyclosporine. Kidney Int 2000; 57: 1100.
    • (2000) Kidney Int , vol.57 , pp. 1100
    • Morris, S.T.1    McMurray, J.J.2    Rodger, S.C.3
  • 10
    • 0034960980 scopus 로고    scopus 로고
    • Cyclosporine is associated with endothelial dysfunction but not with platelet activation in renal transplantation
    • Schrama YC, Dam T, Fijnheer R, et al. Cyclosporine is associated with endothelial dysfunction but not with platelet activation in renal transplantation. Nether J Med 2001; 59: 6.
    • (2001) Nether J Med , vol.59 , pp. 6
    • Schrama, Y.C.1    Dam, T.2    Fijnheer, R.3
  • 11
    • 0024538021 scopus 로고
    • Cyclosporine toxicity on cultured rat microvascular endothelial cells
    • Lau DCW, Wong K-L, Hwang WS. Cyclosporine toxicity on cultured rat microvascular endothelial cells. Kidney Int 1989; 35: 604.
    • (1989) Kidney Int , vol.35 , pp. 604
    • Lau, D.C.W.1    Wong, K.-L.2    Hwang, W.S.3
  • 12
    • 0025797274 scopus 로고
    • Atherosclerosis and lipid disorders after renal transplantation
    • Drueke TB, Abdulmassih Z, Lacour B, et al. Atherosclerosis and lipid disorders after renal transplantation. Kidney Int 1991; 39: S24.
    • (1991) Kidney Int , vol.39
    • Drueke, T.B.1    Abdulmassih, Z.2    Lacour, B.3
  • 13
    • 0027478997 scopus 로고
    • Cyclosporin and serum lipids in renal transplant recipients
    • Kronenberg F, Konig P, Lhotta K, et al. Cyclosporin and serum lipids in renal transplant recipients. Lancet 1993; 341: 765.
    • (1993) Lancet , vol.341 , pp. 765
    • Kronenberg, F.1    Konig, P.2    Lhotta, K.3
  • 14
    • 0026816270 scopus 로고
    • Chronic cyclosporine therapy impairs endothelium-dependent relaxation in the renal artery of the rat
    • Diederich D, Yang Z, Luscher TF. Chronic cyclosporine therapy impairs endothelium-dependent relaxation in the renal artery of the rat. J Am Soc Nephrol 1992; 2: 1291.
    • (1992) J Am Soc Nephrol , vol.2 , pp. 1291
    • Diederich, D.1    Yang, Z.2    Luscher, T.F.3
  • 15
    • 0024348103 scopus 로고
    • Cyclosporin a inhibits endothelium-dependent vasodilation and vascular prostacyclin production
    • Bossaller C, Porstermann U, Hertel R, et al. Cyclosporin A inhibits endothelium-dependent vasodilation and vascular prostacyclin production. Eur J Pharmacol 1989; 165: 165.
    • (1989) Eur J Pharmacol , vol.165 , pp. 165
    • Bossaller, C.1    Porstermann, U.2    Hertel, R.3
  • 16
    • 0028641561 scopus 로고
    • Cyclosporine impairs release of endothelium-derived relaxing factors in epicardial and resistance coronary arteries
    • Sudhir K, MacGregor JS, DeMarco T, et al. Cyclosporine impairs release of endothelium-derived relaxing factors in epicardial and resistance coronary arteries. Circulation 1994; 90: 3018.
    • (1994) Circulation , vol.90 , pp. 3018
    • Sudhir, K.1    MacGregor, J.S.2    DeMarco, T.3
  • 17
    • 0026315526 scopus 로고
    • The role of intrarenal prostaglandins and angiotensin-II in acute cyclosporine-induced vasoconstriction
    • Abraham JS, Bentley FR, Garrison RN. The role of intrarenal prostaglandins and angiotensin-II in acute cyclosporine-induced vasoconstriction. Surgery 1991; 110: 343.
    • (1991) Surgery , vol.110 , pp. 343
    • Abraham, J.S.1    Bentley, F.R.2    Garrison, R.N.3
  • 18
    • 0026014114 scopus 로고
    • Cyclosporine causes sympathetically mediated elevations in arterial pressure in rats
    • Morgan BJ, Lyson T, Sherrer U, et al. Cyclosporine causes sympathetically mediated elevations in arterial pressure in rats. Hypertension 1991; 18: 458.
    • (1991) Hypertension , vol.18 , pp. 458
    • Morgan, B.J.1    Lyson, T.2    Sherrer, U.3
  • 19
    • 0025362468 scopus 로고
    • Role of endothelin in cyclosporine-induced glomerular dysfunction
    • Kon V, Sugiura M, Inagami T, et al. Role of endothelin in cyclosporine-induced glomerular dysfunction. Kidney Int 1990; 37: 1487.
    • (1990) Kidney Int , vol.37 , pp. 1487
    • Kon, V.1    Sugiura, M.2    Inagami, T.3
  • 20
    • 6844225354 scopus 로고
    • Cyclosporine stimulated synthesis of Endothelin by human endothelial cells in tissue culture
    • Bunchaman TE, Brookshire CA. Cyclosporine stimulated synthesis of Endothelin by human endothelial cells in tissue culture. Kidney Int 1990; 37: 365A.
    • (1990) Kidney Int , vol.37
    • Bunchaman, T.E.1    Brookshire, C.A.2
  • 21
    • 0026332004 scopus 로고
    • Dose-dependent effect of cyclosporine on renal arterial resistance in dogs
    • Carrier M, Tronc F, Stewart D, et al. Dose-dependent effect of cyclosporine on renal arterial resistance in dogs. Am J Physiol 1991; 261: H1791.
    • (1991) Am J Physiol , vol.261
    • Carrier, M.1    Tronc, F.2    Stewart, D.3
  • 22
    • 0027471286 scopus 로고
    • Cyclosporine a induces endothelin-1 release from cultured rat vascular smooth muscle cells
    • Takeda Y, Itoh Y, Yoneda T, et al. Cyclosporine A induces endothelin-1 release from cultured rat vascular smooth muscle cells. Eur J Pharmacol 1993; 233: 299.
    • (1993) Eur J Pharmacol , vol.233 , pp. 299
    • Takeda, Y.1    Itoh, Y.2    Yoneda, T.3
  • 23
    • 18344398649 scopus 로고    scopus 로고
    • Cyclosporine a increases nitric oxide activity in vivo
    • Stroes ESG, Luscher TF, de Groot FG, et al. Cyclosporine A increases nitric oxide activity in vivo. Hypertension 1997; 29: 570.
    • (1997) Hypertension , vol.29 , pp. 570
    • Stroes, E.S.G.1    Luscher, T.F.2    De Groot, F.G.3
  • 24
    • 0029944743 scopus 로고    scopus 로고
    • Effects of cyclosporin a on the synthesis, excretion, and metabolism of Endothelin in the rat
    • Abassi ZA, Pieruzzi F, Nakhoul F, et al. Effects of cyclosporin A on the synthesis, excretion, and metabolism of Endothelin in the rat. Hypertension 1996; 27: 1140.
    • (1996) Hypertension , vol.27 , pp. 1140
    • Abassi, Z.A.1    Pieruzzi, F.2    Nakhoul, F.3
  • 25
    • 0025890419 scopus 로고
    • Effects of cyclosporine on plasma Endothelin levels in humans after cardiac transplantation
    • Edwards BS, Hunt SA, Fowler MB, et al. Effects of cyclosporine on plasma Endothelin levels in humans after cardiac transplantation. Am J Cardiol 199l; 67: 782.
    • (1991) Am J Cardiol , vol.67 , pp. 782
    • Edwards, B.S.1    Hunt, S.A.2    Fowler, M.B.3
  • 26
    • 0028980188 scopus 로고
    • Hypertension in cyclosporine A-treated patients is independent of circulating Endothelin levels
    • Forslund T, Hannonen P, Reitamo S, et al. Hypertension in cyclosporine A-treated patients is independent of circulating Endothelin levels. J Intern Med 1995; 238: 71.
    • (1995) J Intern Med , vol.238 , pp. 71
    • Forslund, T.1    Hannonen, P.2    Reitamo, S.3
  • 27
    • 0001261687 scopus 로고    scopus 로고
    • Cyclosporin-induced endothelial dysfunction and hypertension: Are nitric oxide system abnormality and oxidative stress involved
    • Calo L, Semplicini A, Davis PA, et al. Cyclosporin-induced endothelial dysfunction and hypertension: are nitric oxide system abnormality and oxidative stress involved. Transpl Int 2000; 13(Suppl 1): S413.
    • (2000) Transpl Int , vol.13 , Issue.SUPPL. 1
    • Calo, L.1    Semplicini, A.2    Davis, P.A.3
  • 28
    • 0028223439 scopus 로고
    • Cyclosporine produces endothelial dysfunction by increasing production of superoxide
    • Diederich D, Skopec J, Diederich A, et al. Cyclosporine produces endothelial dysfunction by increasing production of superoxide. Hypertension 1994; 23(part 2): 957.
    • (1994) Hypertension , vol.23 , Issue.PART 2 , pp. 957
    • Diederich, D.1    Skopec, J.2    Diederich, A.3
  • 29
    • 0344052668 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and endothelial nitric oxide synthase activity
    • Cosentino F, Luscher TF. Tetrahydrobiopterin and endothelial nitric oxide synthase activity. Cardiovasc Res 1999; 43: 274.
    • (1999) Cardiovasc Res , vol.43 , pp. 274
    • Cosentino, F.1    Luscher, T.F.2
  • 30
    • 0032482975 scopus 로고    scopus 로고
    • Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
    • Vazquez-Vivar J, Kalyanaraman B, Martasek P, et al. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA 1998; 95: 9220.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9220
    • Vazquez-Vivar, J.1    Kalyanaraman, B.2    Martasek, P.3
  • 31
    • 0034979237 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: A critical cofactor for eNOS and a strategy in treatment of endothelial dysfunction?
    • Tiefenbacher CP. Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in treatment of endothelial dysfunction? Am J Physiol Heart Circ Physiol 2001; 280: H2484.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Tiefenbacher, C.P.1
  • 32
    • 0034739459 scopus 로고    scopus 로고
    • Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis
    • Tiefenbacher CP, Bleeke T, Vahl C, et al. Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis. Circulation 2000; 102: 2172.
    • (2000) Circulation , vol.102 , pp. 2172
    • Tiefenbacher, C.P.1    Bleeke, T.2    Vahl, C.3
  • 33
    • 0033967254 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease
    • Maier W, Cosentino F, Lutolf RB, et al. Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease. J Cardiovasc Pharm 2000; 35: 173.
    • (2000) J Cardiovasc Pharm , vol.35 , pp. 173
    • Maier, W.1    Cosentino, F.2    Lutolf, R.B.3
  • 34
    • 0036622464 scopus 로고    scopus 로고
    • Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targets for pharmacologic manipulation
    • Verma S, Maitland A, Weisel RD, et al. Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: identifying cellular targets for pharmacologic manipulation. J Thorac Cardiovasc Surg 2002; 123(6): 1074.
    • (2002) J Thorac Cardiovasc Surg , vol.123 , Issue.6 , pp. 1074
    • Verma, S.1    Maitland, A.2    Weisel, R.D.3
  • 35
    • 0034890205 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelial dysfunction in coronary microcirculation in patients without epicardial coronary artery disease
    • Setoguchi S, Mohri M, Shimokawa H, et al. Tetrahydrobiopterin improves endothelial dysfunction in coronary microcirculation in patients without epicardial coronary artery disease. J Am Coll Cardiol 2001; 38: 493.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 493
    • Setoguchi, S.1    Mohri, M.2    Shimokawa, H.3
  • 36
    • 0033752910 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
    • Heitzer T, Krohn K, Albers S, et al. Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia 2000; 43: 1435.
    • (2000) Diabetologia , vol.43 , pp. 1435
    • Heitzer, T.1    Krohn, K.2    Albers, S.3
  • 37
    • 0034602878 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelial-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
    • Heitzer T, Brockhoff C, Mayer B, et al. Tetrahydrobiopterin improves endothelial-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase. Circ Res 2000; 86: E36.
    • (2000) Circ Res , vol.86
    • Heitzer, T.1    Brockhoff, C.2    Mayer, B.3
  • 38
    • 0037248825 scopus 로고    scopus 로고
    • Nitrotyrosine and 8-isoprostane formation indicate free radical-mediated injury in hearts of patients subjected to cardioplegia
    • Mehlhorn U, Krahwinkel A, Geissler HJ, et al. Nitrotyrosine and 8-isoprostane formation indicate free radical-mediated injury in hearts of patients subjected to cardioplegia. J Thorac Cardiovasc Surg 2003; 125: 178.
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 178
    • Mehlhorn, U.1    Krahwinkel, A.2    Geissler, H.J.3
  • 39
    • 0030851741 scopus 로고    scopus 로고
    • Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat
    • Waugh RJ, Morrow JD, Roberts LJ, et al. Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. Free Radic Biol Med 1997; 23: 943.
    • (1997) Free Radic Biol Med , vol.23 , pp. 943
    • Waugh, R.J.1    Morrow, J.D.2    Roberts, L.J.3
  • 40
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248.
    • (1976) Anal Biochem , vol.72 , pp. 248
    • Bradford, M.M.1
  • 41
    • 0034897674 scopus 로고    scopus 로고
    • Survival and graft function in a large animal lung transplant model after 30 h preservation and substitution of the nitric oxide pathway
    • Hillinger S, Sandera P, Carboni GL, et al. Survival and graft function in a large animal lung transplant model after 30 h preservation and substitution of the nitric oxide pathway. Eur J Cardio Thorac Surg 2001; 20: 508.
    • (2001) Eur J Cardio Thorac Surg , vol.20 , pp. 508
    • Hillinger, S.1    Sandera, P.2    Carboni, G.L.3
  • 42
    • 0032875689 scopus 로고    scopus 로고
    • The nitric oxide synthase co-factor tetrahydrobiopterin reduces allograft ischemia-reperfusion injury after transplantation
    • Schmid RA, Hillinger S, Walter R, et al. The nitric oxide synthase co-factor tetrahydrobiopterin reduces allograft ischemia-reperfusion injury after transplantation. J Thorac Cardiovasc Surg 1999; 118: 726.
    • (1999) J Thorac Cardiovasc Surg , vol.118 , pp. 726
    • Schmid, R.A.1    Hillinger, S.2    Walter, R.3
  • 43
    • 0142058932 scopus 로고    scopus 로고
    • Tetrahydrobioterin and antioxidants reverse the coronary endothelial dysfunction associated with left ventricular hypertrophy in a porcine model
    • Malo O, Desjardins F, Tanguay J-F, et al. Tetrahydrobioterin and antioxidants reverse the coronary endothelial dysfunction associated with left ventricular hypertrophy in a porcine model. Cardiovasc Res 2003; 59: 501.
    • (2003) Cardiovasc Res , vol.59 , pp. 501
    • Malo, O.1    Desjardins, F.2    Tanguay, J.-F.3
  • 44
    • 0036182797 scopus 로고    scopus 로고
    • Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolemia
    • Fukuda Y, Teragawa H, Matsuda K, et al. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolemia. Heart 2002; 87: 264.
    • (2002) Heart , vol.87 , pp. 264
    • Fukuda, Y.1    Teragawa, H.2    Matsuda, K.3
  • 45
    • 0037962138 scopus 로고    scopus 로고
    • Tetrahydrobiopterin restores endothelial dysfunction induced by an oral glucose challenge in healthy subjects
    • Ihlemann N, Rask-Madsen C, Perner A, et al. Tetrahydrobiopterin restores endothelial dysfunction induced by an oral glucose challenge in healthy subjects. Am J Physiol Heart Circ Physiol 2003; 285: H875.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Ihlemann, N.1    Rask-Madsen, C.2    Perner, A.3


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