Local anesthetics as effectors of allosteric gating: Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels

Journal of Clinical Investigation

Volumn 98, Issue 12, 1996, Pages 2874-2886

  Balser, Jeffrey R ^a   Nuss, H Bradley ^a   Orias, David W ^a   Johns, David C ^a   Marban, Eduardo ^a   Tomaselli, Gordon F ^a   Lawrence, John H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Lidocaine; Modulated receptor; Na channels; Single channel recording; Site directed mutagenesis

Indexed keywords

LIDOCAINE; LOCAL ANESTHETIC AGENT; SODIUM CHANNEL;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE; XENOPUS;

ALLOSTERIC REGULATION; ANESTHETICS, LOCAL; ANIMALS; CLONING, MOLECULAR; ELECTROPHYSIOLOGY; LIDOCAINE; MICROINJECTIONS; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; SODIUM CHANNELS; XENOPUS;

EID: 0030465187     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119116     Document Type: Article

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