Preoperative serum interleukin-18 level as a postoperative prognostic marker in patients with gastric carcinoma

Cancer

Volumn 92, Issue 8, 2001, Pages 2050-2055

  Kawabata, Toshinobu ^a,b   Ichikura, Takashi ^a   Majima, Takashi ^a   Seki, Shuhji ^a   Chochi, Kentaro ^a   Takayama, Eiji ^a   Hiraide, Hoshio ^a   Mochizuki, Hidetaka ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b National Defense Medical College Research Institute ^*  (Japan)

Author keywords

Gastric carcinoma; Interleukin 18; Prognostic factor; Serum

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER STAGING; CANCER SURGERY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; SEROLOGY; STOMACH CARCINOMA; SURVIVAL RATE;

AGED; ANTIBODIES, BACTERIAL; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRECTOMY; HELICOBACTER PYLORI; HUMANS; INTERFERON TYPE II; INTERLEUKIN-18; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS;

EID: 0035886468     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20011015)92:8<2050::AID-CNCR1544>3.0.CO;2-5     Document Type: Article

References (24)

1. Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma
2. Serum interleukin-10 levels in patients with advanced gastrointestinal malignancies
3. Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma
4. Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression
5. Cloning of a new cytokine that induces IFN-gamma production by T cells
6. Cytokine production and killer activity of NK/T-NK cells derived with IL-2, IL-15, or the combination of IL-12 and IL-18
7. Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-gamma production
8. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB
9. Overview of interleukin-18: More than an interferon-gamma inducing factor
10. IFN-gamma-dependent and independent mechanisms in adverse effects caused by concomitant administration of IL-18 and IL-12
11. Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18
12. Augmentation by interleukin-18 of MHC-nonrestricted killer activity of human peripheral blood mononuclear cells in response to interleukin-12
13. Modulation of interleukin-18 expression in human colon carcinoma: Consequences for tumor immune surveillance
14. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils
15. IL-18 is a potent coinducer of IL-13 in NK and T cells: A new potential role for IL-18 in modulating the immune response
16. In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4+ T cells
17. TNM classification of malignant tumors. 5th ed.
18. Increased levels of circulating interleukin-18 in patients with advanced tuberculosis
19. Elevated interleukin (IL)-18 levels during acute graft-versus-host disease after allogeneic bone marrow transplantation
20. Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively
21. Correlation of serum cytokine and adhesion molecule determinations with pregnancy outcome
22. IL-18 induction of IgE: Dependence on CD4+ T cells, IL-4 and STAT6
23. Tumor escape mechanisms from immunosurveillance: Induction of unresponsiveness in a specific MHC-restricted CD4+ human T cell clone by the autologous MHC class II+ melanoma
24. High incidence of interleukin 10 mRNA but not interleukin 2 mRNA detected in human breast tumours