Identification of protease and ADP-ribose 1″-monophosphatase activities associated with transmissible gastroenteritis virus non-structural protein 3

Journal of General Virology

Volumn 87, Issue 3, 2006, Pages 651-656

  Putics, Ákos ^a   Gorbalenya, Alexander E ^b   Ziebuhr, John ^a,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADP RIBOSE 1' MONOPHOSPHATASE; NONSTRUCTURAL PROTEIN 3; PROTEINASE; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME; VIRUS RNA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; ENZYME ANALYSIS; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TRANSLATION REGULATION; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIRUS TRANSCRIPTION;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CELL LINE; GASTROENTERITIS, TRANSMISSIBLE, OF SWINE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PAPAIN; PEPTIDE HYDROLASES; PHOSPHORIC MONOESTER HYDROLASES; RECOMBINANT PROTEINS; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIRAL NONSTRUCTURAL PROTEINS;

DNA VIRUSES; RNA VIRUSES; TRANSMISSIBLE GASTROENTERITIS VIRUS;

EID: 33644586288     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81596-0     Document Type: Article

References (41)

1. Almazán, F., Galán, C. & Enjuanes, L. (2004). The nucleoprotein is required for efficient coronavirus genome replication. J Virol 78, 12683-12688.
2. Anand, K., Palm, G. J., Masters, J. R., Siddell, S. G., Ziebuhr, J. & Hilgenfeld, R. (2002). Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra α-helical domain. EMBO J 21, 3213-3224.
3. pro) structure: basis for design of anti-SARS drugs. Science 300, 1763-1767.
4. Bhardwaj, K., Guarino, L. & Kao, C. C. (2004). The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor. J Virol 78, 12218-12224.
5. Bonilla, P. J., Hughes, S. A. & Weiss, S. R. (1997). Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus strain A59. J Virol 71, 900-909.
6. Brierley, I., Boursnell, M. E. G., Binns, M. M., Bilimoria, B., Blok, V. C., Brown, T. D. K. & Inglis, S. C. (1987). An efficient ribosomal frame-shifting signal in the polymerase-encoding region of the coronavirus IBV. EMBO J 6, 3779-3785.
7. Dong, S. & Baker, S. C. (1994). Determinants of the p28 cleavage site recognized by the first papain-like cysteine proteinase of murine coronavirus. Virology 204, 541-549.
8. Draker, R., Roper, R. L., Petric, M. & Tellier, R. (2006). The complete sequence of the bovine torovirus genome. Virus Res 115, 56-68.
9. Eleouet, J.-F., Rasschaert, D., Lambert, P., Levy, L., Vende, P. & Laude, H. (1995). Complete sequence (20 kilobases) of the polyprotein-encoding gene 1 of transmissible gastroenteritis virus. Virology 206, 817-822.
10. Genschik, P., Hall, J. & Filipowicz, W. (1997). Cloning and characterization of the Arabidopsis cyclic phosphodiesterase which hydrolyzes ADP-ribose 1″,2″-cyclic phosphate and nucleoside 2′,3′-cyclic phosphates. J Biol Chem 272, 13211-13219.
11. González, J. M., Gomez-Puertas, P., Cavanagh, D., Gorbalenya, A. E. & Enjuanes, L. (2003). A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae. Arch Virol 148, 2207-2235.
12. Gorbalenya, A. E., Koonin, E. V., Donchenko, A. P. & Blinov, V. M. (1989). Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis. Nucleic Acids Res 17, 4847-4861.
13. Gorbalenya, A. E., Koonin, E. V. & Lai, M. M. C. (1991). Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, α-and coronaviruses. FEBS Lett 288, 201-205.
14. Harcourt, B. H., Jukneliene, D., Kanjanahaluethai, A., Bechill, J., Severson, K. M., Smith, C. M., Rota, P. A. & Baker, S. C. (2004). Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity. J Virol 78, 13600-13612.
15. Hegyi, A. & Ziebuhr, J. (2002). Conservation of substrate specificities among coronavirus main proteases. J Gen Virol 83, 595-599.
16. Herold, J., Gorbalenya, A. E., Thiel, V., Schelle, B. & Siddell, S. G. (1998). Proteolytic processing at the amino terminus of human coronavirus 229E gene 1-encoded polyproteins: identification of a papain-like proteinase and its substrate. J Virol 72, 910-918.
17. 2+-binding finger connecting the two domains of a papain-like fold. J Biol Chem 274, 14918-14925.
18. Ivanov, K. A. & Ziebuhr, J. (2004). Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5′-triphosphatase activities. J Virol 78, 7833-7838.
19. Ivanov, K. A., Hertzig, T., Rozanov, M., Bayer, S., Thiel, V., Gorbalenya, A. E. & Ziebuhr, J. (2004a). Major genetic marker of nidoviruses encodes a replicative endoribonuclease. Proc Natl Acad Sci U S A 101, 12694-12699.
20. Ivanov, K. A., Thiel, V., Dobbe, J. C., van der Meer, Y., Snijder, E. J. & Ziebuhr, J. (2004b). Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. J Virol 78, 5619-5632.
21. Kanjanahaluethai, A. & Baker, S. C. (2000). Identification of mouse hepatitis virus papain-like proteinase 2 activity. J Virol 74, 7911-7921.
22. Karras, G. I., Kustatscher, G., Buhecha, H. R., Allen, M. D., Pugieux, C., Sait, F., Bycroft, M. & Ladurner, A. G. (2005). The macro domain is an ADP-ribose binding module. EMBO J 24, 1911-1920.
23. Lim, K. P. & Liu, D. X. (1998). Characterization of the two overlapping papain-like proteinase domains encoded in gene 1 of the coronavirus infectious bronchitis virus and determination of the C-terminal cleavage site of an 87-kDa protein. Virology 245, 303-312.
24. Lim, K. P., Ng, L. F. P. & Liu, D. X. (2000). Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus Avian infectious bronchitis virus and characterization of the cleavage products. J Virol 74, 1674-1685.
25. Lu, Y., Lu, X. & Denison, M. R. (1995). Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59. J Virol 69, 3554-3559.
26. Putics, Á., Filipowicz, W., Hall, J., Gorbalenya, A. E. & Ziebuhr, J. (2005). ADP-ribose-1″-monophosphatase: a conserved coronavirus enzyme that is dispensable for viral replication in tissue culture. J Virol 79, 12721-12731.
27. Sawicki, S. G. & Sawicki, D. L. (1995). Coronaviruses use discontinuous extension for synthesis of subgenome-length negative strands. Adv Exp Med Biol 380, 499-506.
28. Sawicki, S. G. & Sawicki, D. L. (1998). A new model for coronavirus transcription. Adv Exp Med Biol 440, 215-219.
29. Schelle, B., Karl, N., Ludewig, B., Siddell, S. G. & Thiel, V. (2005). Selective replication of coronavirus genomes that express nucleocapsid protein. J Virol 79, 6620-6630.
30. Seybert, A., Hegyi, A., Siddell, S. G. & Ziebuhr, J. (2000). The human coronavirus 229E superfamily 1 helicase has RNA and DNA duplex-unwinding activities with 5′-to-3′ polarity. RNA 6, 1056-1068.
31. Shi, S. T. & Lai, M. M. C. (2005). Viral and cellular proteins involved in coronavirus replication. Curr Top Microbiol Immunol 287, 95-131.
32. Siddell, S. G., Ziebuhr, J. & Snijder, E. J. (2005). Coronaviruses, toroviruses, and arteriviruses. In Topley and Wilson's Microbiology and Microbial Infections, 10th edn, pp. 823-856. Edited by B. W. J. Mahy & V. ter Meulen. London: Hodder Arnold.
33. Snijder, E. J., Bredenbeek, P. J., Dobbe, J. C. & 7 other authors (2003). Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol 331, 991-1004.
34. Thiel, V., Ivanov, K. A., Putics, Á. & 9 other authors (2003). Mechanisms and enzymes involved in SARS coronavirus genome expression. J Gen Virol 84, 2305-2315.
35. van der Hoek, L., Pyrc, K., Jebbink, M. F. & 7 other authors (2004). Identification of a new human coronavirus. Nat Med 10, 368-373.
36. Ziebuhr, J. (2005). The coronavirus replicase. Curr Top Microbiol Immunol 287, 57-94.
37. Ziebuhr, J. & Siddell, S. G. (1999). Processing of the human coronavirus 229E replicase polyproteins by the virus-encoded 3C-like proteinase: identification of proteolytic products and cleavage sites common to pp1a and pp1ab. J Virol 73, 177-185.
38. Ziebuhr, J., Herold, J. & Siddell, S. G. (1995). Characterization of a human coronavirus (strain 229E) 3C-like proteinase activity. J Virol 69, 4331-4338.
39. Ziebuhr, J., Snijder, E. J. & Gorbalenya, A. E. (2000). Virus-encoded proteinases and proteolytic processing in the Nidovirales. J Gen Virol 81, 853-879.
40. Ziebuhr, J., Thiel, V. & Gorbalenya, A. E. (2001). The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond. J Biol Chem 276, 33220-33232.
41. Zúñiga, S., Sola, I., Alonso, S. & Enjuanes, L. (2004). Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis. J Virol 78, 980-994.