The Autocatalytic Release of a Putative RNA Virus Transcription Factor from Its Polyprotein Precursor Involves Two Paralogous Papain-like Proteases that Cleave the Same Peptide Bond

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 33220-33232

  Ziebuhr, John ^a   Thiel, Volker ^a   Gorbalenya, Alexander E ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; DISEASES; ENZYMES; RNA; SYNTHESIS (CHEMICAL); VIRUSES;

AUTOPROCESSING MECHANISMS;

BIOCHEMISTRY;

PAPAIN; POLYPROTEIN; PROTEIN PRECURSOR; PROTEINASE; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN; MESSENGER RNA; PRIMER DNA; RECOMBINANT PROTEIN; VIRUS PROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; AVIAN INFECTIOUS BRONCHITIS VIRUS; CHEMICAL BOND; CONTROLLED STUDY; CORONAVIRUS; DNA FLANKING REGION; ENZYME MECHANISM; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; MESSENGER RNA SYNTHESIS; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RNA VIRUS; SEQUENCE ANALYSIS; VIRUS GENOME; AMINO ACID SEQUENCE; ANIMAL; CATALYSIS; CATTLE; CELL LINE; CHEMISTRY; FIBROBLAST; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; POLYMERASE CHAIN REACTION; PROBABILITY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AVES; AVIAN INFECTIOUS BRONCHITIS VIRUS; CORONAVIRUS; HUMAN CORONAVIRUS 229E; MURINAE; MURINE HEPATITIS VIRUS; RNA VIRUSES;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATALYSIS; CATTLE; CELL LINE; CONSERVED SEQUENCE; CORONAVIRUS; CORONAVIRUS 229E, HUMAN; CORONAVIRUS, BOVINE; DNA PRIMERS; ENDOPEPTIDASES; FIBROBLASTS; HUMANS; INFECTIOUS BRONCHITIS VIRUS; MARKOV CHAINS; MICE; MOLECULAR SEQUENCE DATA; MURINE HEPATITIS VIRUS; OPEN READING FRAMES; PAPAIN; PHYLOGENY; POLYMERASE CHAIN REACTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA VIRUSES; RNA, MESSENGER; RNA, VIRAL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; VIRAL PROTEINS;

EID: 0035980126     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104097200     Document Type: Article

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