Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence

Journal of Pharmacology and Experimental Therapeutics

Volumn 309, Issue 3, 2004, Pages 1174-1182

  Fiorucci, Stefano ^a,d   Distrutti, Eleonora ^a   Mencarelli, Andrea ^a   Rizzo, Giovanni ^a   Di Lorenzo, Anna Rita ^a   Baldoni, Monia ^a   Del Soldato, Piero ^b   Morelli, Antonio ^a   Wallace, John L ^c  

^a UNIVERSITY OF PERUGIA   (Italy)

^b NicOx SA   (France)

^c UNIVERSITY OF CALGARY   (Canada)

^d POLICLINICO MONTELUCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; CELECOXIB; CYCLIC GMP; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DIETHYLENETRIAMINE; DITHIOTHREITOL; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTOXIN; HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LIPOXIN; LIPOXIN A; N TERT BUTOXYCARBONYL METHIONYLLEUCYLPHENYLALANINE; N(G) NITROARGININE METHYL ESTER; NAPROXEN; NITRIC OXIDE; PADGEM PROTEIN; PROSTAGLANDIN E2; PROTEIN P50; RECEPTOR BLOCKING AGENT; ROFECOXIB; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; COCULTURE; CONTROLLED STUDY; DNA BINDING; DRUG ACETYLATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; ICOSANOID METABOLISM; NEUTROPHIL; NITROSYLATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CELL ADHESION; CELLS, CULTURED; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; HUMANS; LIPOXINS; NEUTROPHILS; NITRIC OXIDE;

EID: 2442684102     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.063651     Document Type: Article

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