Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation

European Journal of Pharmacology

Volumn 532, Issue 1-2, 2006, Pages 24-31

  Aoike, Futoshi ^a   Takahashi, Masanori P ^a   Sakoda, Saburo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Anti arrhythmia agent; Flecainide; Myotonia; Patch clamp technique; Sodium channel

Indexed keywords

ANTIARRHYTHMIC AGENT; FLECAINIDE; MEXILETINE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ARTICLE; CELL CULTURE; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IC 50; MUSCLE ACTION POTENTIAL; MUSCLE CELL; MUSCLE EXCITATION; MYOTONIA; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; SODIUM CURRENT;

ANTI-ARRHYTHMIA AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLECAINIDE; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MEXILETINE; MUSCLE, SKELETAL; MYOTONIA; PATCH-CLAMP TECHNIQUES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 33644523380     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.12.021     Document Type: Article

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