The pharmacologic treatment of muscle pain

Anesthesiology

Volumn 101, Issue 2, 2004, Pages 495-526

  Cohen, Steven P ^a,c   Mullings, Rohan ^b   Abdi, Salahadin ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMITRIPTYLINE; ANTICONVULSIVE AGENT; ANTIHISTAMINIC AGENT; BENZODIAZEPINE DERIVATIVE; BOTULINUM TOXIN; CAFFEINE; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; CARNITINE; CORTICOSTEROID; CYCLOBENZAPRINE; DIPYRONE; DOSULEPIN; GABAPENTIN; MAGNESIUM; MUSCLE RELAXANT AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NAFTIDROFURYL; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PHENYTOIN; PHOSPHODIESTERASE INHIBITOR; QUININE; SEROTONIN AGONIST; SUMATRIPTAN; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VITAMIN;

ANALGESIC ACTIVITY; CERVICAL DYSTONIA; CHRONIC DAILY HEADACHE; CLINICAL TRIAL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DYSTONIA; FIBROMYALGIA; HEADACHE; HUMAN; HYPOTENSION; LOW BACK PAIN; MUSCLE CRAMP; MYALGIA; MYOFASCIAL PAIN; PRIORITY JOURNAL; REVIEW; SIDE EFFECT; TEMPOROMANDIBULAR JOINT DISORDER;

ANIMALS; CLINICAL TRIALS; HUMANS; MUSCLE, SKELETAL; MUSCULAR DISEASES; PAIN;

EID: 3342967577     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200408000-00032     Document Type: Review

References (324)

1. Long DM, BenDebba M, Torgerson WS, Dawson EG, Hardy RW, Robertson JT, Sypert GW, Watts C: Persistent back pain and sciatica in the United States: Patient characteristics. J Spinal Disord 1996; 9:40-58
2. Skootsky SA, Jaeger B, Oye RK: Prevalence of myofascial pain in general internal medicine practice. West J Med 1989; 151:157-60
3. Gerwin RD: Classification, epidemiology, and natural history of myofascial pain syndrome. Curr Pain Headache Rep 2001; 5:412-20
4. Simons DG, Mense S: Understanding and measurement of muscle tone as related to clinical muscle pain. Pain 1998; 75:1-17
5. Borg-Stein J, Simons DG: Myofascial pain. Arch Phys Med Rehabil 2002; 83(suppl 1):S40-7
6. Maekawa K, Clark GT, Kuboki T: Intramuscular hypoperfusion, adrenergic receptors and chronic muscle pain. J Pain 2002; 3:251-60
7. Suvinen TI, Hanes KR, Gerschman JA, Reade PC: Psychophysical subtypes of temporomandibujar disorders. J Orofac Pain 1997; 11:200-5
8. London LH, Shulman B, Diamond S: The role of psychometric testing and psychological treatment in tension-type headache. Curr Pain Headache Rep 2001; 5:467-71
9. Alvarez DJ, Rockwell PG: Trigger points: Diagnosis and management. Am Fam Physician 2002; 65:653-60
10. Bennett RM: Emerging concepts in the neurobiology of chronic pain: Evidence of abnormal sensory processing in fibromyalgia. Mayo Clin Proc 1999; 74:385-98
11. Simons DG: Muscular pain syndromes, Advances in Pain Research and Therapy. Vol 17. Edited by Friction JR, Awad E. New York, Raven Press, 1990, p 1
12. Wright A, Graven-Nielsen T, Davies I, Arendt-Nielsen L: Temporal summation of pain from skin, muscle and joint following nociceptive ultrasonic stimulation in humans. Exp Brain Res 2002; 144:475-82
13. Graven-Nielsen T, Arendt-Nielsen L: Peripheral and central sensitization in musculoskeletal pain disorders: An experimental approach. Curr Rheumatol Rep 2002; 4:313-21
14. Hoheisel U, Mense S, Simons DG, Yu X-M: Appearance of new receptive fields in rat dorsal horn neurons following noxious stimulation of skeletal muscle: A model for referral of muscle pain? Neurosci Lett 1993; 153:9-12
15. Lance JW, Curran DA: Treatment of chronic tension headache. Lancet 1964; 42:1236-9
16. Woodforde JM, Dwyer B, McEwen BW, DeWilde FW, Bleasel K, Connelley TJ, Ho CY: Treatment of postherpetic neuralgia. Med J Anst 1965; 1:869-72
17. Eschalier A, Mestre C, Dubrya C, Ardid D: Why are antidepressants effective as pain relief? CNS Drugs 1994; 2:261-7
18. Eschalier A, Ardid D, Dubray C: Tricyclic and other antidepressants as analgesics, Novel Aspects of Pain Management: Opioids and Beyond. Edited by Sawynok J, Cowan A. New York, Wiley, 1999, pp 303-20
19. Cohen SP, Abdi S: New developments in the use of tricyclic antidepressants for the management of pain. Curr Opin Anaesthesiol 2001; 14:505-11
20. Feinmann C, Harris M, Cawley R: Psychogenic facial pain: Presentation and treatment. BMJ 1984; 288:436-8
21. Sharav Y, Singer E, Schmidt E, Dionne RA, Dubner R: The analgesic effect of amitriptyline on chronic facial pain. Pain 1987; 31:199-209
22. Plesh O, Curtis D, Levine J, McCall WD Jr: Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. J Oral Rehabil 2000; 27:834-41
23. Diamond S, Baltes BJ: Chronic tension headaches treated with amitriptyline: A double-blind study. Headache 1971; 11:110-6
24. Bendtsen L, Jensen R: Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. Cephalagia 2000; 20:603-10
25. McQuay H, Carroll D, Jadad AR, Wiffen P, Moore A: Anticonvulsant drugs for management of pain: A systematic review. BMJ 1995; 311:1047-52
26. Spierings EL, Schroevers M, Honkoop PC, Sorbi M: Presentation of chronic daily headache: A clinical study. Headache 1998; 38:191-6
27. Manzoni GC, Granella F, Sandrini G, Cavallini A, Zanferrari C, Nappi G: Classification of chronic daily headache by International Headache Society criteria: Limits and new proposals. Cephalagia 1995; 15:37-43
28. Fragoso YD, Carrazana EJ: Low doses of gabapentin may be helpful in the management of chronic daily headache. MedGenMed 2000; 2:E52
29. Mathew NT, Ali S: Valproate in the treatment of persistent chronic daily headache: An open label study. Headache 1991; 31:71-4
30. Rosenberg JM, Harrell C, Ristic H, Werner RA, de Rosayro AM: The effect of gabapentin on neuropathic pain. Clin J Pain 1997; 13:251-5
31. Serrao M, Rossi P, Cardinali P, Valente G, Parisi L, Pierelli F: Gabapentin treatment for muscle cramps: An open-label trial. Clin Neuropharmacol 2000; 23:45-9
32. Hatta V, Saxena A, Kaul HL: Phenytoin reduces suxamethonium-induced myalgia. Anaesthesia 1992; 47:664-7
33. Brown BR, Womble J: Cyclobenzaprine in intractable pain syndromes with muscle spasm. JAMA 1978; 240:1151-2
34. Bercel NA: Cyclobenzaprine in the treatment of skeletal muscle spasm in osteoarthritis of the cervical and lumbar spine. Curr Ther Res 1977; 22:462-8
35. Basmajian JV: Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: Two double-blind controlled clinical and laboratory studies. Arch Phys Med Rehabil 1978; 59:58-63
36. Schwanz L, Kutscher AH, Yavelow I, Cobin HP, Brod MS: Carisoprodol in the management of temporomandibular joint pain and dysfunction: A preliminary report. Ann N Y Acad Sci 1960; 86:245-9
37. Greene CS, Laskin DM: Meprobamate therapy for the myofascial pain-dysfunction (MPD) syndrome: A double-blind evaluation. JADA 1971; 82:587-90
38. Herman CR, Schiffman EL, Look JO: The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: A randomized, clinical trial. J Orofac Pain 2002; 16:64-79
39. Singer EJ, Dionne RA: A controlled evaluation of ibuprofen and diazepam for chronic orofacial muscle pain. J Orofac Pain 1997; 11:139-46
40. Browning R, Jackson JL, O'Malley PG: Cyclobenzaprine and back pain: A meta-analysis. Arch Intern Med 2001; 161:1613-20
41. Fryda-Kaurimsky Z, Muller-Fassbender H: Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: A controlled trial comparing tizanidine and diazepam. J Int Med Res 1981; 9:501-5
42. Lepisto P: A comparative trial of tizanidine and placebo in patients with skeletal-muscle spasms after operation for herniated disk. Curr Ther Res 1981; 30:141-6
43. Fogelholm R, Murros M: Tizanidine in chronic tension-type headache: A placebo controlled double-blind cross-over study. Headache 1992; 32:509-13
44. Shimomura T, Awaki E, Kowa H, Takahashi K: Treatment of tension-type headache with tizanidine hydrochloride: Its efficacy and relationship to the plasma MHPG concentration. Headache 1991; 31:601-4
45. Murros K, Kataja M, Hedman C, Havanka H, Sato E, Farkkila M, Peltola J, Keranen T: Modified-release formulation of tizanidine in chronic tension-type headache. Headache 2000; 40:633-7
46. Taricco M, Adone R, Pagliacci C, Telaro E: Pharmacological interventions for spasticity following spinal cord injury. Cochrane Database Syst Rev 2000; 2:CD00131
47. Penn RD, Savoy SM, Corcos D, Latash M, Gottlieb G, Parke B, Kroin JS: Intrathecal baclofen for severe spinal spasticity. N Engl J Med 1989; 320:1517-21
48. Hugenholts H, Nelson RF, Dehoux E, Bickerton R: Intrathecal baclofen for intractable spinal spasticity: A double blind crossover study in eight patients. Can J Neurol Sci 1992; 19:188-93
49. Nance PW, Bugaresti J, Shellenberger K, Sheremata W, Martinez-Arizala A: Efficacy and safety of tizanidine in the treatment of spasticity in patients with spinal cord injury. North American Tizanidine Study Group. Neurology 1994; 44(suppl 9):S44-51
50. Shakespeare DT, Boggild M, Young C: Anti-spasticity agents for multiple sclerosis. Cochrane Database Syst Rev 2001; 4:CD001332
51. Feldman RG, Kelly-Hayes M, Conomy JP, Foley JM: Baclofen for spasticity in multiple sclerosis: Double-blind crossover and three-year study. Neurology 1978; 28:1094-8
52. Smith C, Birnbaum G, Carter JI, Greenstein J, Lublin FD: Tizanidine treatment of spasticity caused by multiple sclerosis: Results of a double-blind, placebo-controlled trial. Neurology 1994; 44(suppl 9):S34-42
53. United Kingdom Tizanidine Trial Group: A double-blind, placebo-controlled trial of tizanidine in the treatment of spasticity caused by multiple sclerosis. Neurology 1994; 44(suppl 9):S70-8
54. Flacco L, Colozzi A, Ripari P, Pieralisi G: Dantrolene sodium in traumatic muscle contracture: Double-blind clinical and pharmacological trial. Clin Ther 1989: 11:623-32
55. Christian JM: Treatment of muscle spasms with oral dantrolene sodium. Oral Surg Oral Med Oral Pathol 1989; 67:268-70
56. Bertorini T, Palmieri G, Bhattacharya S: Beneficial effects of dantrolene sodium in exercise-induced muscle pains: Calcium mediated? Lancet 1982; 1:616-7
57. Collier CB: Dantrolene and suxamethonium: The effect of pre-operative dantrolene on the action of suxamethonium. Anaesthesia 1979; 34:152-8
58. Brennum J, Kjeklsen M, Olesen J: The 5-HT-like agonist sumatriptan has a significant effect in chronic tension-type headache. Cephalagia 1992; 12:375-9
59. Cady RK, Gutterman D, Saiers JA, Beach ME: Responsiveness of non-IHS migraine and tension-type headache to sumatriptan. Cephalagia 1997; 17:588-90
60. Olesen J: Clinical and pathophysiological observations in migraine and tension-type headache explained by integration of vascular, supraspinal and myofascial inputs. Pain 1991; 46:125-32
61. Bono G, Micieli G, Sances G, Calvani M, Nappi G: L-5HTP treatment in primary headaches: An attempt at clinical identification of responsive patients. Cephalagia 1984; 4:159-65
62. Dao TT, Lund JP, Remillard G, Lavigne GJ: Is myofascial pain of the temporal muscles relieved by oral sumatriptan? A cross-over pilot study. Pain 1995; 62:241-4
63. Harrison SD, Balawi SA, Feinmann C, Harris M: Atypical fascial pain: A double-blind placebo-controlled crossover pilot study of subcutaneous sumatriptan. Eur Neuropsychopharmacol 1997; 7:83-8
64. Nappi G, Sandrini G, Granella F, Ruiz F, Cerutti G, Facchinetti F, Blandini F, Manzoni GC: A new 5-HT2 antagonist (ritanserin) in the treatment of chronic headache with depression: A double-blind study vs amitriptyline. Headache 1990; 30:439-44
65. Jain KK: An evaluation of intrathecal ziconotide for the treatment of chronic pain. Expert Opin Investig Drugs 2000; 9:2403-10
66. Choe H, Kim JS, Ko SH, Kim DC, Han YJ, Song HS: Epidural verapamil reduces analgesic consumption after lower abdominal surgery. Anesth Analg 1998; 86:786-90
67. Staats PS, Yearwood T, Charapata SG, Presley RW, Wallace MS, Byas-Smith M, Fisher R, Bryce DA, Mangieri EA, Luther RR, Mayo M, McGuire D, Ellis D: Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: A randomized controlled trial. JAMA 2004; 291:63-70
68. Micieli G, Sances G, Pacchetti C, Trucco M, Magri M, Piazza D: Flunarizine: A wide spectrum prophylactic for migraine headache. Int J Clin Pharm Res 1984; 3:239-45
69. Micieli G, Piazza D, Sinforiani E, Cavallini A, Trucco M, Gabellini S, Mancuso A, Pacchetti C: Antimigraine drugs in the management of daily chronic headaches: Clinical profiles of responsive patients. Cephalagia 1985; 5(suppl 20):219-24
70. Shukla R, Garg RK, Nag D, Ahuja RC: Nifedipine in migraine and tension headache: A randomized double blind crossover study. J Assoc Physicians India 1995; 43:770-2
71. Peer G, Blum M, Aviram A: Relief of hemodialysis-induced muscular cramps by nifedipine. Dialysis Transplant 1983; 12:180-1
72. Baltodano N, Gallo BV, Weidler DJ: Verapamil vs. quinine in recumbent nocturnal leg cramps in the elderly. Arch Intern Med 1988; 148:1969-70
73. Linde B, Hjemdahl P, Freyschuss U, Juhlin-Dannfelt A: Adipose tissue and skeletal muscle blood flow during mental stress. Am J Physiol 1989; 256:E12-8
74. Maekawa K, Kuboki T, Miyawaki T, Shimada M, Yamashita A, Clark GT: Effect of intravenous infusion of an alpha-adrenergic blocking agent on the haemodynamic changes in human masseter muscle induced by cold pressor stimulation. Arch Oral Biol 1999; 44:319-27
75. Acero CO Jr, Kuboki T, Maekawa K, Yamashita A, Clark GT: Haemodynamic responses in chronically painful, human trapezius muscle to cold pressor stimulation. Arch Oral Biol 1999; 44:805-12
76. Larsson SE, Alund M, Cai H, Oberg PA: Chronic pain after soft-tissue injury of the cervical spine: Trapezius muscle blood flow and cloctromyography at static loads and fatigue. Pain 1994; 57:173-80
77. Denaro A, Martucci N, Ruggieri S, Manna V, Agnoli A: Headache and noradrenergic involvement: The effects of alpha 2-stimulants and alpha 2-antagonists. Acta Psychiatr Scand Suppl 1985; 320:20-5
78. Kaplan B, Wang T, Rammohan M, del Greco F, Molteni A, Atkinson AJ Jr: Response to head-up tilt in cramping and noncramping hemodialysis patients. Int J Clin Pharmacol Ther Toxicol 1992; 30:173-80
79. Sidhom OA, Odeh YK, Krumlovsky FA, Budris WA, Wang Z, Pospisil PA, Atkinson AJ Jr: Low-dose prazosin in patients with muscle cramps during hemodialysis. Clin Pharmacol Ther 1994; 56:445-51
80. Stein C, Schafer M, Machelska H: Attacking pain at its source: New perspectives on opioids. Nat Med 2003; 9:1003-8
81. Fishman SM, Wilsey B, Mahajan G, Molina P: Methadone reincarnated: Novel clinical applications with related concerns. Pain Med 2002; 3:339-48
82. Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL, Jacoby HI, Selve N: Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol. J Pharmacol Exp Ther 1993; 267:331-40
83. Schnitzer RJ, Gray WL, Paster RZ, Kamin M: Efficacy of tramadol in treatment of chronic low back pain. J Rheumatol 2000; 27:772-8
84. Biasi G, Manca S, Manganelli S, Marcolongo R: Tramadol in the fibromyalgia syndrome: A controlled clinical trial versus placebo. Int J Clin Pharmacol Res 1998; 18:13-9
85. Moulin DE, Iezzi A, Amireh R, Sharpe WK, Boyd D, Merskey H: Randomised trial of oral morphine for chronic non-cancer pain. Lancet 1996; 347:143-7
86. List T, Tegelberg A, Haraldson T. Isacsson G: Intra-articular morphine as analgesic in temporomandibular joint arthralgia/osteoarthritis. Pain 2001; 94: 275-82
87. Friedman AP: Assessment of Fiorinal with codeine in the treatment of tension headache. Clin Ther 1986; 8:703-21
88. Harden RN, Rogers D, Fink K, Gracely RH: Controlled trial of ketorolac in headache. Neurology 1998; 50:507-9
89. Hennies OL: A new skeletal muscle relaxant (DS 103-282*) compared to diazepam in the treatment of muscle spasm of local origin. J Int Med Res 1981; 9:62-8
90. Aigony L, Fondras JC, Pajot J, Schoeffler P, Woda A: Intrathecal midazolam versus intrathecal morphine in orofacial nociception: An experimental study in rats. Neurosci Lett 1992; 139:97-9
91. Nakanishi O, Amano Y, Ishikawa T, Azuma M, Imamura Y: Effects of midazolam on pain sensations in the face. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 84:11-5
92. Singer E, Dionne R: A controlled evaluation of ibuprofen and diazepam for chronic orofacial muscle pain. J Orofac Pain 1997; 11:139-46
93. Jagger RG: Diazepam in the treatment of temporomandibular joint dysfunction syndrome: A double blind study. J Dent 1973; 2:37-40
94. Stiesch-Scholz M, Fink M, Tschernitschek H, Rossbach A: Medical and physical therapy of temporomandibular joint disk displacement without reduction. Cranio 2002; 20:85-90
95. Harkins S, Linford J, Cohen J, Kramer T, Cueva L: Administration of clonazepam in the treatment of TMD and associated myofascial pain: A double-blind pilot study. J Craniomandib Disord Facial Oral Pain 1991; 5:179-86
96. DeNucci DJ, Sobiski C, Dionne RA: Triazolam improves sleep but fails to alter pain in TMD patients. J Orofac Pain 1998; 12:116-23
97. Eisenberg M, Balsley S, Katz RL: Effects of diazepam on succinylcholine-induced myalgia, potassium increase, creatine phosphokinase elevation, and relaxation. Anesth Analg 1979; 58:314-7
98. Verma RS: Diazepam and suxamethonium muscle pain (a dose-response study). Anaesthesia 1982; 37:688-90
99. Verma RS, Chatterji S, Mathur N: Diazepam and succinylcholine-induced muscle pains. Anesth Analg 1978; 57:295-7
100. Davies AO: Oral diazepam premedication reduces the incidence of post-succinylcholine muscle pains. Can Anaesth Soc J 1983; 30:603-6
101. Chestnutt WN, Lowry KG, Dundee JW, Pandit SK, Mirakhur RK: Failure of two benzodiazepines to prevent suxamethonium-induced muscle pain. Anaesthesia 1985; 40:263-9
102. Manchikanti L: Diazepam does not prevent succinylcholine-induced fasciculations and myalgia: A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. Acta Anaesthesiol Scand 1984; 28:523-8
103. Fisher QA, Fisher E, Matjasko MJ: Midazolam pretreatment does not ameliorate myoglobinemia or the clinical side effects of succinylcholine. J Clin Anesth 1993; 5:414-8
104. Shukla R, Nag D, Ahuja RC: Alprazolam in chronic tension type headache. J Assoc Physicians India 1996; 44:641-4
105. Weber MG: The treatment of muscle contraction headaches with diazepam. Curr Ther Res 1973; 14:210-6
106. Hackett GI, Boddie HG, Harrison P: Chronic muscle contraction headache: The importance of depression and anxiety. J R Soc Med 1987; 80:689-91
107. Paiva T, Nunes S, Moreira A, Santos J, Teixeira J, Barbosa A: Effects of frontalis EMG biofeedback and diazepam in the treatment of tension headache. Headache 1982; 22:216-20
108. Price DD, Mao J, Mayer DJ: Central neural mechanisms of normal and abnormal pain states, Progress in Pain Research and Management. Vol 1. Edited by Fields HL, Liebeskind JC. Seattle, IASP Press, 1994, pp 61-83
109. Hewitt DJ: The use of NMDA-receptor antagonists in the treatment of chronic pain. Clin J Pain 2000; 16:S73-9
110. Moiniche S, Kehlet H, Dahl JB: A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief. ANESTHESIOLOGY 2002; 96:725-41
111. Svensson P, Cairns BE, Wang K, Hu JW, Graven-Nielsen T, Arendt-Nielsen L, Sessle BJ: Glutamate-evoked pain and mechanical allodynia in the human masseter muscle. Pain 2003; 101:221-7
112. Cairns BE, Hu JW, Arendt-Nielsen L, Sessle BJ, Svensson P: Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle. J Neurophysiol 2001; 86:782-91
113. Chandrasekharan NV, Dai H, Roos KL, Evanson NK, Tomsik J, Elton TS, Simmons DL: COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci U S A 2002; 99:13926-31
114. Schwab JM, Schluesener HJ, Meyermann R, Serhan CN: COX-3: Just another COX or the solitary elusive target of paracetamol? Lancet 2003; 361: 981-2
115. Simmons DL: Variants of cyclooxygenase-1 and their roles in medicine. Thromb Res 2003; 110:265-8
116. Semark A, Noakes TD, St. Clair Gibson A, Lambert MI: The effect of a prophylactic dose of flurbiprofen on muscle soreness and sprinting performance in trained subjects. J Sports Sci 1999; 17:197-203
117. Lecomte JM, Lacroix VJ, Montgomery DL: A randomized controlled trial of the effect of naproxen on delayed onset muscle soreness and muscle strength. Clin J Sport Med 1998; 8:82-7
118. Dudley GA, Czerkawski J, Meinrod A, Gillis G, Baldwin A, Scarpone M: Efficacy of naproxen sodium for exercise-induced dysfunction muscle injury and soreness. Clin J Sport Med 1997; 7:3-10
119. Baixauli F, Ingles F, Alcantara P, Navarrete R, Puchol E, Vidai F: Percutaneous treatment of acute soft tissue lesions with naproxen gel and ketoprofen gel. J Int Med Res 1990; 18:372-8
120. Machen J, Whitefield M: Efficacy of a proprietary ibuprofen gel in soft tissue injuries: A randomised, double-blind, placebo-controlled study. Int J Clin Pract 2002; 56:102-6
121. Patel RK, Leswell PF: Comparison of ketoprofen, piroxicam, and diclofenac gels in the treatment of acute soft-tissue injury in general practice. General Practice Study Group. Clin Ther 1996; 18:497-507
122. Svennson P, Houe L, Arendt-Nielsen L: Effect of systemic versus topical nonsteroidal anti-inflammatory drugs on postexercise jaw-muscle soreness: A placebo-controlled study. J Orofac Pain 1997; 11:353-62
123. Steen KH, Wegner H, Meller ST: Analgesic profile of peroral and topical ketoprofen upon low pH-induced muscle pain. Pain 2001; 93:23-33
124. Shin SM, Choi JK: Effect of indomethacin phonophoresis on the relief of temporomandibular joint pain. Cranio 1997; 15:345-8
125. Frost A: Diclofenac versus lidocaine as injection therapy in myofascial pain. Scand J Rheumatol 1986; 15:153-6
126. Affaitati G, Vecchiet F, Lerza R, De Laurentis S, Iezzi S, Festa F, Giamberardino MA: Effects of topical diclofenac (DHEP plaster) on skin, subcutis and muscle pain thresholds in subjects without spontaneous pain. Drugs Exp Clin Res 2001; 27:69-76
127. Lange R, Lentz R: Comparison of ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache. Drugs Exp Clin Res 1995; 21:89-96
128. Mongini F, Bona G, Garnero M, Gloria A: Efficacy of meclofenamate sodium versus placebo in headache and craniofacial pain. Headache 1993; 33: 22-8
129. Steiner TJ, Lange R: Ketoprofen (25 mg) in the symptomatic treatment of episodic tension-type headache: Double-blind placebo-controlled comparison with acetaminophen (1000 mg). Cephalagia 1998; 18:38-43
130. Packman B, Packman E, Doyle G, Cooper S, Ashraf E, Koronkiewicz K, Jayawardena S: Solubilized ibuprofen: Evaluation of onset, relief, and safety of a novel formulation in the treatment of episodic tension-type headache. Headache 2000; 40:561-7
131. Schachtel BP, Furey SA, Thoden WR: Nonprescription ibuprofen and acetaminophen in the treatment of tension-type headache. J Clin Pharmacol 1996:36:1120-5
132. Mehlisch DR, Weaver M, Fladung B: Ketoprofen, acetaminophen and placebo in the treatment of tension headache. Headache 1998; 38:579-89
133. van den Berghe LI, de Boever JA, Schautteet H: Double-blind clinical study of piroxicam as adjuvant in the treatment of the pain and dysfunction of temporomandibular joints. Cranio 1986; 4:352-6
134. Ekberg E: Treatment of temporomandibular disorders of arthrogenous origin. Swed Dent J Suppl 1998; 131:1-57
135. Thie NM, Prasad NG, Major PW: Evaluation of glucosamine sulfate compared to ibuprofen for the treatment of temporomandibular joint osteoarthritis: A randomized double-blind controlled 3 month clinical trial. J Rheumatol 2001; 28:1347-55
136. Simon LS: Biologic effects of nonsteroidal anti-inflammatory drugs. Curr Opin Rheumatol 1997; 9:178-82
137. Brandt KD: Should nonsteroidal anti-inflammatory drugs be used to treat osteoarthritis? Rheum Dis Clin North Am 1993; 19:29-44
138. Drovanti A, Bignamini AA, Rovati AL: Therapeutic activity of oral glucosamine sulphate in osteoarthrosis: A placebo-controlled double-blind investigation. Clin Ther 1980; 3:160-72
139. Tapadinhas MJ, Rivera IC, Bignamini AA: Oral glucosamine sulphate in the management of arthrosis: Report on a multi-centre open investigation in Portugal. Pharmatherapeutica 1982; 3:157-68
140. Truelove EL: The chemotherapeutic management of chronic and persistent orofacial pain. Dent Clin North Am 1994; 38:669-88
141. Dionne RA, Berthold CW: Therapeutic uses of non-steroidal anti-inflammatory drugs in dentistry. Crit Rev Oral Biol Med 2001; 12:315-30
142. Woolsey RM, Tureen LL, Murphy MQ: The relief of muscle spasm and pain with chlormezanone and chlormezanone with aspirin: A blind, crossover study. Curr Ther Res 1966; 8:52-5
143. Amlie E, Weber H, Holme I: Treatment of acute low-back pain with piroxicam: Results of a double-blind placebo-controlled trial. Spine 1987; 12: 473-6
144. Pohjolainen T, Jekunen A, Autio L, Vuorela H: Treatment of acute low back pain with the COX-2 selective anti-inflammatory drug nimesulide. Spine 2000; 25:1579-85
145. Veenema KR, Leahey N, Schneider S: Ketorolac versus meperidine: ED treatment of severe musculoskeletal low back pain. Am J Emerg Med 2000; 18:404-7
146. Naguib M, Farag H, Magbagbeola JA: Effect of pre-treatment with lysine acetyl salicylate on suxamethonium-induced myalgia. Br J Anaesth 1987; 59: 606-10
147. Kahraman S, Ercan S, Aypar U, Erdem K: Effect of pre-operative i.m. administration of diclofenac on suxamethonium-induced myalgia. Br J Anaesth 1993; 71:238-41
148. Leeson-Payne CG, Nicoll JM, Hobbs GJ: Use of ketorolac in the prevention of suxamethonium myalgia. Br J Anaesth 1994; 73:788-90
149. Scott AB: Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery. Ophthalmology 1980; 87:1044-9
150. Tsui JK, Eisen A, Stoessl AJ, Calne S, Calne JB: Double-blind study of botulinum toxin in spasmodic torticollis. Lancet 1986; 2:245-7
151. Borodic GE, Acquadro M, Johnson EA: Botulinum toxin therapy for pain and inflammatory disorders: Mechanisms and therapeutic effects. Expert Opin Investig Drugs 2001; 10:1531-4
152. Ishikawa H, Mitsui Y, Yoshitomi T, Mashimo K, Aoki S, Mukuno K, Shimizu K: Presynaptic effects of botulinum toxin type A on the neuronally evoked response of albino and pigmented rabbit iris sphincter and dilator muscles. Jpn J Ophthalmol 2000; 44:106-9
153. Welch MJ, Purkiss JR, Foster KA: Sensitivity of embryonic rat dorsal root ganglia neurons to clostridium botulinum neurotoxins. Toxicon 2000; 38:245-58
154. Aoki KR: Evidence for antinociceptive activity of botulinum toxin type A in pain management. Headache 2003; 43(suppl 1):S9-15
155. Binder WJ, Brin MF, Blitzer A, Schoenrock LD, Pogoda JM: Botulinum toxin type A (BOTOX) for treatment of migraine headaches: An open-label study. Otolaryngol Head Neck Surg 2000; 123:669-76
156. Brans JW, Lindeboom RN, Snoek JW, Zwarts MJ, van Weerden TW, Brunt ER, van Hilten JJ, van der Kamp W, Prins MH, Speelman JD: Botulinum toxin versus trihexylphenidyl in cervical dystonia: A prospective, randomized, double-blind controlled trial. Neurology 1996; 46:1066-72
157. Lew MF, Adornato BT, Duane DD, Dykstra DD, Factor SA, Massey JM, Brin MF, Jankovic J, Rodnitzky RL, Singer C, Swenson MR, Tarsy D, Murray JJ, Koller M, Wallace JD: Botulinum toxin type B: A double-blind, placebo-controlled, safety and efficacy study in cervical dystonia. Neurology 1997; 49:701-7
158. Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M: Safety and efficacy of Neurobloc (botulinum toxin type B) in type A-resistant cervical dystonia. Neurology 1999; 53:1431-8
159. Foster L, Clapp L, Erickson M, Jabbari B: Botulinum toxin A and chronic low back pain: A randomized, double-blind study. Neurology 2001; 56:1290-3
160. Childers MK, Wilson DJ, Gnatz SM, Conway RR, Sherman AK: Botulinum toxin type A in piriformis muscle syndrome: A pilot study. Am J Phys Med Rehabil 2002; 81:751-9
161. Fishman LM, Anderson C, Rosner B: BOTOX and physical therapy in the treatment of piriformis syndrome. Am J Phys Med Rehabil 2002; 81:936-42
162. Wheeler AH, Goolkasian P, Gretz SS: A randomized, double-blind, prospective pilot study of botulinum toxin injection for refractory, unilateral, cervicothoracic, paraspinal, myofascial pain syndrome. Spine 1998; 23:1662-7
163. Porta M: A comparative trial of botulinum toxin type A and methylprednisolone for the treatment of myofascial pain syndrome and pain from chronic muscle spasm. Pain 2000; 85:101-5
164. Smuts JA, Baker MK, Smuts HM, Stassen R, Rossouw E, Barnard PW: Prophylactic treatment of chronic tension-type headache using botulinum toxin type A. Eur J Neurol 1999; 6(suppl 4):S99-102
165. Porta M: A comparative trial of botulinum toxin A and methylprednisolone for the treatment of tension-type headache. Curr Rev Pain 2000; 4:31-5
166. Relja M: Treatment of tension-type headache by local injection of botulinum toxin. Eur J Neurol 1997; 4(suppl 2):S71-3
167. Schmitt WJ, Slowey E, Fravi N, Weber S, Burgunder J-M: Effect of botulinum toxin A injections in the treatment of chronic tension-type headache: A double-blind, placebo-controlled trial. Headache 2001; 41:658-64
168. Zwart J-A, Bovim G, Sand T, Sjaastad O: Tension headache: Botulinum toxin paralysis of temporal muscles. Headache 1994; 34:458-62
169. Rollnik JD, Karst M, Fink M, Dengler R: Botulinum toxin type A and EMG: A key to the understanding of chronic tension-type headaches? Headache 2001; 41:985-9
170. Rollnik JD, Tanneberger O, Schubert M, Schneider U, Dengler R: Treatment of tension-type headache with botulinum toxin type A: A double-blind, placebo-controlled study. Headache 2000; 40:300-5
171. Freund BJ, Schwanz M: Use of botulinum toxin in chronic whiplash-associated disorder. Clin J Pain 2002; 18:5163-8
172. Nederhand MJ, Ijzerman MJ, Hermens HJ, Baten CT, Zilvold G: Cervical muscle dysfunction in the chronic whiplash associated disorder grade II (WAD-II). Spine 2000; 25:1938-43
173. Freund BJ, Schwartz M: Treatment of whiplash associated with neck pain with botulinum toxin-A: A pilot study. J Rheumatol 2000; 27:481-4
174. Freund BJ, Schwartz M: Treatment of chronic cervical-associated headache with botulinum toxin A: A pilot study. Headache 2000; 40:231-6
175. Borodic GE, Acquadro MA: The use of botulinum toxin for the treatment of chronic facial pain. J Pain 2002; 3:21-7
176. von Lindern JJ, Niederhagen B, Berge S, Appel T: Type A botulinum toxin in the treatment of chronic facial pain associated with masticatory hyperactivity. J Oral Maxillofac Surg 2003; 61:774-8
177. Freund B, Schwartz M, Symington JM: Botulinum toxin: New treatment for temporomandibular disorders. Br J Oral Maxillofac Surg 2000; 38:466-71
178. von Lindern JJ: Type A botulinum toxin in the treatment of chronic facial pain associated with temporo-mandibular dysfunction. Acta Neurol Belg 2001; 101:39-41
179. Mathias B, Dillingham T, Zeigler D, Chang A, Belandres P: Topical capsaicin for chronic neck pain. Am J Phys Med Rehabil 1995; 74:39-44
180. Moss HK, Herrmann LG: Use of quinine for relief of 'night cramps' in the extremities. JAMA 1940; 115:1358-9
181. Gotnick A: Night cramps and quinine. Arch Intern Med 1943; 71:555-62
182. Jones K, Castleden CM: A double-blind comparison of quinine sulphate and placebo in muscle cramps. Age Ageing 1983; 12:155-8
183. Jansen PH, Veenhuizen KC, Verbeek AL, Straatman H: Efficacy of hydroquinine in preventing frequent ordinary muscle cramp outlasts actual administration. Lancet 1997; 349:528-32
184. Lee FY, Lee SD, Tsai YT, Lai KH, Chao Y, Lin HC, Wang SS, Lo KJ: A randomized controlled trial of quinidine in the treatment of cirrhotic patients with muscle cramps. J Hepatol 1991; 12:236-40
185. Fung MC, Holbrook JH: Placebo-controlled trial of quinine therapy for nocturnal leg cramps. West J Med 1989; 151:42-4
186. Diener HC, Dethlefsen U, Dethlefsen-Gruber S, Verbeek P: Effectiveness of quinine in treating muscle cramps: A double-blind, placebo-controlled, parallel-group, multicentre trial. Int J Clin Pract 2002; 56:243-6
187. Kaji DM, Ackad A, Nottage WG, Stein RM: Prevention of muscle cramps in hemodialysis patients by quinine sulphate. Lancet 1976; 2:66-7
188. Lim SH: Randomised double-blind trial comparison of quinine sulphate for nocturnal leg cramps. Br J Clin Pract 1986; 40:462
189. Warburton A, Royston JP, O'Neill CJ, Nicholson PW, Jee RD, Denham MJ, Dobbs SM, Dobbs RJ: A quinine a day keeps the leg cramps away? Br J Clin Pharmacol 1987; 23:459-65
190. Sidorov J: Quinine sulfate for leg cramps: Does it work? J Am Geriatr Soc 1993; 41:498-500
191. Dahle LO, Berg G, Hummar M, Hurtig M, Larsson L: The effect of oral magnesium substitution on pregnancy-induced leg cramps. Am J Obstet Gynecol 1995; 173:175-80
192. Roffe C, Sills S, Crome P, Jones P: Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps. Med Sci Monit 2002; 8:CR326-30
193. Frusso R, Zarate M, Augustovski F, Rubinstein A: Magnesium for the treatment of nocturnal leg cramps: A cross over randomized trial. J Fam Pract 1999; 48:868-71
194. Butler JV, Mulkerrin EC, O'Keefe ST: Nocturnal leg cramps in older people. Postgrad Med J 2002; 76:596-8
195. Del Mar CB, Glasziou PP, Spinks AP, Sanders SL, Hilton DJ: Treatment alternatives for nocturnal leg cramps (commentary). Med J Aust 2001; 174:540
196. Young JB, Connolly MJ: Naftidrofuryl treatment for rest cramp. Postgrad Med J 1993; 69:624-6
197. Medina Santillan R, Reyes Garcia G, Sanchez Mejia JL, Mateos Garcia E: Dexamethasone alone versus dexamethasone plus complex B vitamins in the therapy of low back pain. Proc West Pharmacol Soc 2000; 43:69-70
198. Reyes-Garcia G, Medina-Santillan R, Castillo-Henkel E, Rodriguez-Silverio J, Teran-Rosales F, Mateos-Garcia E: Analgesic effect of sodium diclofenac plus vitamin B complex in the PIFIR model. Proc West Pharm Soc 1999; 42:91-92
199. Allgood VE, Oakley RH, Cidlowski JA: Modulation by vitamin B6 of glucocorticoid receptor-mediated gene expression requires transcription factors in addition to the glucocorticoid receptor. J Biol Chem 1993; 268:20870-6
200. Roca AO, Jarjoura D, Blend D, Cugino A, Rutecki GW, Nuchikat PS, Whittier FC: Dialysis leg cramps: Efficacy of quinine versus vitamin E. ASAIO J 1992; 38:M481-5
201. Khajehdehi P, Mojerlou M, Behzadi S, Rais-Jalali GA: A randomized, double-blind, placebo-controlled trial of supplementary vitamins E, C and their combination for treatment of haemodialysis cramps. Nephrol Dial Transplant 2001; 16:1448-51
202. Connolly PS, Shirley EA, Wasson JH, Nierenberg DW: Treatment of nocturnal leg cramps: A crossover trial of quinine vs vitamin E. Arch Intern Med 1992; 152:1877-80
203. Watanabe M, Tabata T, Huh JI, Inai T, Tsuboi A, Sasaki K, Endo Y: Possible involvement of histamine in muscular fatigue in temporomandibular disorders: Animal and human studies. J Dent Res 1999; 78:769-75
204. Gerschman JA, Reade PD, Burrows GD: Evaluation of a proprietary analgesic/antihistamine in the management of pain associated with temporomandibular joint pain dysfunction syndrome. Aust Dent J 1984; 29:300-4
205. Sawynok J, Yaksh TL: Caffeine as an analgesic adjuvant: A review of pharmacology and mechanisms of action. Pharmacol Rev 1993; 45:43-85
206. Migliardi JR, Armellino JJ, Friedman M, Gillings DB, Beaver WT: Caffeine as an analgesic adjuvant in tension headache. Clin Pharmacol Ther 1994; 50: 576-86
207. Waul N, Whitney C, Avery D, Dunner D: The analgesic effects of caffeine in headache. Pain 1991; 44:151-5
208. Schachtel BP, Thoden WR, Konerman JP, Brown A, Chaing DS: Headache pain model for assessing and comparing the efficacy of over-the counter analgesic agents. Clin Pharmacol Ther 1991; 50:322-9
209. Diamond S, Balm TK, Freitag FG: Ibuprofen plus caffeine in the treatment of tension-type headache. Clin Pharmacol Ther 2000; 68:312-9
210. Borges J, Zavaleta C: Study of a new analgesic compound in the treatment of tension headache. J Int Med Res 1976; 4:74-8
211. Wojcicki J, Samochowiec L, Lawczynski L, Szwed G, Olszewska M: A double-blind comparative evaluation of aspirin, paracetamol and paracetamol + caffeine (Finimal) for their analgesic effectiveness. Arch Immunol Ther Exper (Warsz) 1977; 25:175-9
212. Gorlich HD, von Gablenz E, Steinberg HW: Treatment of nocturnal leg cramps. A multicenter, double blind, placebo controlled comparison between the combination of quinine and theophylline ethylene diamine with quinine (in German). Arzneimittelforschung 1991; 41:167-75
213. Martinez-Martin P, Raffaelli E Jr, Titus F, Despuig J, Fragoso YD, Diez-Tejedor E, Liano H, Leira R, Cornet ME, van Toor BS, Camara J, Peil H, Vix JM, Ortiz P, Cooperative Study Group: Efficacy and safety of metamizol vs. acetylsalicylic acid in patients with moderate episodic tension-type headache: A randomized, double-blind, placebo- and active-controlled, multicentre study. Cephalagia 2001; 21:604-10
214. Bigal ME, Bordini CA, Speciali JG: Intravenous metamizol (Dipyrone) in acute migraine treatment and episodic tension-type headache: A placebo-controlled study. Cephalagia 2001; 21:90-5
215. Bigal ME, Bordini CA, Speciali JG: Intravenous dipyrone for the treatment of episodic tension-type headache: A randomized, placebo-controlled, double-blind study. Braz J Med Biol Res 2002; 35:1139-45
216. Lujan M, Lopez-Fiesco A, Lopez y Martinez E, Zamora Lopez G, Alvarez Rueda M: Experimental tension headache in humans: A double blind comparison of the analgesic effect of Dipyrone, naproxen plus paracetamol or placebo. Proc West Pharmacol Soc 1992; 35:201-5
217. Bellinghieri G, Savica V, Mallamace A, Di Stefano C: Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients. Am J Clin Nutr 1983; 38:523-31
218. Ahmad S, Robertson HT, Golper TA, Wolfson M, Kurtin P, Katz LA, Hirschberg R, Nicora R, Ashbrook DW, Kopple JD: Multicenter trial of L-carnitine in maintenance hemodialysis patients: II. Clinical and biochemical effects. Kidney Int 1990; 38:912-8
219. Bourke E, Moynagh PN: Antiinflammatory effects of glucocorticoids in brain cells, independent of NF-kappa B. J Immunol 1999; 163:2113-9
220. Wenneberg B, Kopp S: Short-term effect of intra-articular injections of a corticosteroid on temporomandibular joint pain and dysfunction. Swed Dent J 1978; 2:189-96
221. Kopp S, Wenneberg B: Effects of occlusal treatment and intraarticular injections on temporomandibular joint pain and dysfunction. Acta Odontol Scand 1981; 39:87-96
222. Kopp S, Carlsson GE, Haraldson T, Wenneberg B: Long-term effect of intra-articular injections of sodium hyaluronate and corticosteroid on temporomandibular joint arthritis. J Oral Maxillofac Surg 1987; 45:929-35
223. J. Majwer K, Swider M: Results of treatment with ionophoresis of posttraumatic changes of temporomandibular joints with an apparatus of own design [in Polish]. Protet Stomatol 1989; 39:172-6
224. Reid KI, Dionne RA, Sicard-Rosenbaum L, Lord D, Dubner RA: Evaluation of iontophoretically applied dexamethasone for painful pathologic temporomandibular joints. Oral Surg Oral Med Oral Pathol 1994; 77:605-9
225. Aggarwal S, Kumar A: A cortisone-wrecked and bony alkylosed TMJ. Plast Reconstr Surg 1986; 83:1084-5
226. Acton CH: Steroid-induced anterior open bite: Case report. Aust Dent J 1986; 31:455-8
227. Sfikakis PP, Mitsikostas DD, Manoussakis MN, Foukaneli D, Moutsopoulos HM: Headache in systemic lupus erythematosus: A controlled study. Br J Rheumatol 1998; 37:300-3
228. Leong KH, Boey ML: Inflammatory myopathies. Singapore Med J 1992; 33:186-8
229. Polsonetti BW, Joy SD, Laos LF: Steroid-induced myopathy in the ICU. Ann Pharmacother 2002; 36:1741-4
230. Bird SJ, Rich MM: Critical illness myopathy and polyneuropathy. Curr Neurol Neurosci Rep 2002; 2:527-33
231. Fogelholm R, Murros K: Maprotiline in chronic tension headache: A double-blind, crossover study. Headache 1985; 25:273-5
232. Indaco A, Carried PB: Amitriptyline in the treatment of headache in patients with Parkinson's disease: A double-blind placebo-controlled study. Neurology 1988; 38:1720-2
233. Langemark M, Loldrup D, Bech P, Diesen J: Clomipramine and mianserin in the treatment of chronic tension headache: A double-blind, controlled study. Headache 1990; 30:118-21
234. Sjaastad O: So-called 'tension headache'-The response to a 5-HT uptake inhibitor: Femoxetine. Cephalagia 1983; 3:53-60
235. Saper JR, Silberstein SD, Lake AE III, Winters ME: Double-blind trial of fluoxetine: Chronic daily headache and migraine. Headache 1994; 34:497-502
236. Manna V, Bolino F, DiCicco L: Chronic tension-type headache, mood depression, and serotonin: Therapeutic effects of fluvoxamine and mianserine. Headache 1994; 34:44-9
237. Gobel H, Hamouz V, Hansen C, Heininger K, Hirsch S, Lindner V, Heuss D, Soyka D: Chronic tension-type headache: Amitriptyline reduces clinical headache-duration and experimental pain but does not alter pericranial muscle activity readings. Pain 1994; 59:241-9
238. Singh NN, Misra S: Sertraline in chronic tension-type headache. J Assoc Physicians India 2002; 50:873-8
239. Pfaffenrath V, Diener HC, Isler H, Meyer C, Scholz E, Taneri Z, Wessely P, Zaiser-Kasehel H, Haase W, Fischer W: Efficacy and tolerability of amitriptylinoxide in the treatment of chronic tension-type headache: A multi-centre controlled study. Cephalagia 1994; 14:149-55
240. Langemark M, Olesen J: Sulpiride and paroxetine in the treatment of chronic tension-type headache: An explanatory double-blind trial. Headache 1994; 34:20-4
241. Lascelles RG: Atypical facial pain and depression. Br J Psychiatry 1966; 112:651-9
242. Rizzatti-Barbosa CM, Nogueira MT, de Andrade ED, Ambrosano GM, de Albergaria Barbosa JR: Clinical evaluation of amitriptyline for the control of chronic pain caused by temporomandibular joint disorders. Cranio 2003; 21: 221-5
243. Headache Classification Committee of the International Headache Society: Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalagia 1988; 8(suppl 7):1-96
244. Franks AST: Mandibular muscle spasm: A double-blind study of a muscle relaxant drug. Br J Clin Prac 1965; 19:281-8
245. Basmajian JV: Acute back pain and spasm: A controlled multicenter trial of combined analgesic and antispasm agents. Spine 1989; 14:438-9
246. Larsson B, Melin L, Doberi A: Recurrent tension headache in adolescents treated with self-help relaxation training and a muscle relaxant drug. Headache 1990; 30:665-71
247. Borenstein DG, Lacks S, Wiesel SW: Cyclobenzaprine and naproxen versus naproxen alone in the treatment of acute low back pain and muscle spasm. Clin Ther 1990; 12:125-31
248. Valtonen EJ: A controlled clinical trial of chlormezanone, orphenadrine, orphenadrine/paracetamol and placebo in the treatment of painful skeletal muscle spasms. Ann Clin Res 1975; 7:85-8
249. Miller AR: A comparative study of Parafon Forte tablets and Soma compound in the treatment of painful skeletal muscle conditions. Curr Ther Res 1976; 19:444-50
250. Vernon WG: A double-blind study of Parafon Forte in the treatment of musculo-skeletal back conditions. Curr Ther Res 1972; 14:801-6
251. Scheiner JJ: Evaluation of a combined muscle relaxant-analgesic as an effective therapy for painful skeletal muscle spasm. Curr Ther Res 1972; 14: 168-77
252. Atkinson D: A single dose placebo-controlled study to assess the effectiveness of adding a muscle relaxant to a compound analgesic in the treatment of tension headache. J Int Med Res 1979; 7:560-63
253. Diamond S: Double-blind study of metaxalone: Use as skeletal-muscle relaxant. JAMA 1966; 195:479-80
254. Perchuk E, Weinreb M, Aksu A: A new treatment for nocturnal leg cramps. Angiology 1961; 12:102-4
255. Turturro MA, Frater CR, D'Amico FJ: Cyclobenzaprine with ibuprofen versus ibuprofen alone in acute myofascial strain: A randomized, double-blind clinical trial. Ann Emerg Med 2003; 41:818-26
256. Borenstein DG, Korn S: Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: Results of two placebo-controlled trials. Clin Ther 2003; 25:1056-73
257. Tuzun F, Unalan H, Oner N, Ozguzel H, Kirazli Y, Icagasioglu A, Kuran B, Tuzun S, Basar G: Multicenter, randomized, double-blinded, placebo-controlled trial of thiocolchicoside in acute low back pain. Joint Bone Spine 2003; 70: 356-61
258. Lipton RB, Stewart WF, Cady R, Hall C, O'Quinn S, Kuhn T, Gutterman D: Sumatriptan for the range of headaches in migraine sufferers: Results of the Spectrum Study. Headache 2000; 40:783-91
259. Roldan OV, Maglione H, Carreira R, Mainieri S: Piroxicam, diazepam and placebo in the treatment of temporomandibular joint dysfunction. Double blind study (in Spanish). Rev Assoc Odontol Argent 1990; 78:83-5
260. Bouchier-Hayes TA, Rotman H, Darekar BS: Comparison of the efficacy and tolerability of diclofenac gel (Voltarol Emulgel) and felbinac gel (Traxam) in the treatment of soft tissue injuries. Br J Clin Pract 1990; 44:319-20
261. Birch S, Jamison RN: Controlled trial of Japanese acupuncture for chronic myofascial neck pain: Assessment of specific and nonspecific effects of treatment. Clin J Pain 1998; 14:248-55
262. Prior MJ, Cooper KM, May LG, Bowen DL: Efficacy and safety of acetaminophen and naproxen in the treatment of tension-type headache: A randomized, double-blind, placebo-controlled trial. Cephalagia 2002; 22:740-8
263. Kubitzek F, Ziegler G, Gold MS, Liu JM, Ionescu E: Low-dose diclofenac potassium in the treatment of episodic tension-type headache. Eur J Pain 2003; 7:155-62
264. Steiner TJ, Lange R, Voelker M: Aspirin in episodic tension-type headache: Placebo-controlled dose-ranging comparison with paracetamol. Cephalagia 2003; 23:59-66
265. Cheshire WP, Abashian SW, Mann JD: Botulinum toxin in the treatment of myofascial pain syndrome. Pain 1994; 59:65-9
266. Keizer SB, Rutten HP, Pilot P, Morre HH, v Os JJ, Verburg AD: Botulinum toxin injection versus surgical treatment for tennis elbow: A randomized pilot study. Clin Orthop 2002; 401:125-31
267. Nixdorf DR, Heo G, Major PW: Randomized controlled trial of botulinum toxin A for chronic myogenous orofacial pain. Pain 2002; 99:465-73
268. Jordan SE, Ahn SS, Freischlag JA, Gelabert HA, Machleder HI: Selective botulinum chemodenervation of the scalene muscles for treatment of neurogenic thoracic outlet syndrome. Ann Vase Surg 2000; 14:365-9
269. Ondo WG, Vuong KD, Derman HS: Botulinum toxin A for chronic daily headache: A randomized, placebo-controlled, parallel design study. Cephalagia 2004; 24:60-5
270. Catto GRD, Smith FW, MacLeod M: Treatment of muscle cramps during maintenance haemodialysis. BMJ 1973; 3:389-90
271. Jansen PH, Veenhuizen KC, Verbeek AL, Straatman H: Efficacy of hydroquinine in preventing ordinary muscle cramp outlasts actual administration. J Neurol Sci 1994; 122:157-61
272. Thorpe P: Controlled and uncontrolled studies on "Fiorinal-PA" for symptomatic relief in tension headache. Med J Aust 1970; 2:180-1
273. Kagan G, Masheter HC: A controlled study of short-term treatment of tension headache. Curr Med Res Opin 1978; 5:709-13
274. Dao TT, Knight K, Ton-That V: Modulation of myofascial pain by the reproductive hormones: A preliminary report. J Prosthet Dent 1998; 79:663-70
275. Lin Y, Pape H-D, Friedrich R: Use of superoxide dismutase (SOD) in patients with temporomandibular joint dysfunction: A preliminary study. Int J Oral Maxillofac Surg 1994; 23:428-9
276. Guidotti FP, Dilluvio V: Oral treatment of skeletal muscle spasm with fluphenazine alone and combined with orphenadrine. Curr Ther Res Clin Exp 1965; 7:693-6
277. Ayres S Jr, Mihan R: Nocturnal leg cramps (systremma): A progress report on response to vitamin E. South Med J 1974; 67:1308-12
278. Saltman PBL: Syndol in the treatment of tension headache. Med Proc 1973; 19:35-7
279. Scheepers F: Syndol in the treatment of tension headache. Med Proc 1971; 17:359-68
280. Bigal ME, Bordini CA, Speciali JG: Intravenous chlorpromazine in the treatment of episodic tension-type headache: A randomized, placebo controlled, double-blind study. Ar Qneuropsiquiatr 2002; 60:537-41
281. Bengtsson A, Henriksson KG, Larsson J: Reduced high-energy phosphate levels in the painful muscles of patients with primary fibromyalgia. Arthritis Rheum 1986; 29:817-21
282. Lindman R, Eriksson A, Thornell LE: Fiber type composition of the human female trapezius muscle: Enzyme-histochemical characteristics. Am J Anat 1991; 190:385-92
283. Lindman R, Hagberg M, Angqvist KA, Soderlund K, Hultman E, Thornell LE: Changes in muscle morphology in chronic trapezius myalgia. Scand J Work Environ Health 1991; 17:347-55
284. Simms RW: Fibromyalgia is not a muscle disorder. Am J Med Sci 1998; 315:346-50
285. Staud R, Vierck CJ, Cannon RL, Mauderli AP, Price DD: Abnormal sensitization and temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome. Pain 2001; 91:165-75
286. Staud R, Cannon RC, Mauderli AP, Robinson ME, Price DD, Vierck CJ Jr: Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome. Pain 2003; 102:87-95
287. Ernberg M, Voog U, Alstergren P, Lundeberg T, Kopp S: Plasma and serum serotonin levels and their relationship to orofacial pain and anxiety in fibromyalgia. J Orofac Pain 2000; 14:37-46
288. Schwarz MJ, Spath M, Muller-Bardorff H, Pongratz DE, Bondy B, Ackenheil M: Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum fibromyalgia patients. Neurosci Lett 1999; 259:196-8
289. Larson AA, Giovengo SL, Russel IJ, Michalek JE: Changes in the concentrations of amino acids in the cerebrospinal fluid that correlate with pain in patients with fibromyalgia: Implications for nitric oxide pathways. Pain 2000; 87:201-11
290. Griep EN, Boersma JW, Lentjes EG, Prins AP, van der Korst JK, de Kloet ER: Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain. J Rheumatol 1998; 25:1374-81
291. Salemi S, Rethage, Wollina U, Michel BA, Gay RE, Gay S, Sprott H: Detection of interleukin 1beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha in skin of patients with fibromyalgia. J Rheumatol 2003; 30:146-50
292. Stand R: Evidence of involvement of central neural mechanisms in generating fibromyalgia pain. Curr Rheumatol Rep 2002; 4:299-305
293. Bussone G: Chronic migraine and chronic tension-type headache: Different aspects of the chronic daily headache spectrum. Clinical and pathogenetic considerations. Neurol Sci 2003; 24(suppl 2):S90-3
294. Jensen R: Peripheral and central mechanisms in tension-type headache: An update. Cephalagia 2003; 23(suppl 1):49-52
295. Fusco M, D'Andrea G, Micciche F, Stecca A, Bernardini D, Cananzi AL: Neurogenic inflammation in primary headaches. Neurol Sci 2003; 24(suppl 2): S61-4
296. Sandrini G, Antonaci F, Pucci E, Bono G, Nappi G: Comparative study with EMG, pressure algometry and manual palpation in tension-type headache and migraine. Cephalagia 1994; 14:451-7
297. Altura BM, Altura BT: Tension headaches and muscle tension: Is there a role for magnesium? Med Hypotheses 2001; 57:705-13
298. Difazio M, Jabbari B: A focused review of the use of botulinum toxins for low back pain. Clin J Pain 2002; 18:5155-62
299. Ambroz C, Scott A, Ambroz A, Talbott EO: Chronic low back pain assessment using surface electromyography. J Occup Environ Med 2000; 42: 660-9
300. Nelson BW, O'Reilly E, Miller M, Hogan M, Wegner JA, Kelly C: The clinical effects of intensive, specific exercise on chronic low back pain: A controlled study of 895 consecutive patients with 1-year follow up. Orthopedics 1995; 18:971-81
301. Leinonen V, Kankaanpaa M, Luukkonen M, Kansanen M, Hannimen O, Airaksinen O, Taimela S: Lumbar paraspinal muscle function, perception of lumbar position, and postural control in disc herniation-related back pain. Spine 2003; 28:842-8
302. Stonier CS: Phenomenology, epidemiology, and natural progression of the muscular temporomandibular disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83:77-81
303. List T, Dworkin SF: Comparing TMD diagnoses and clinical findings at Swedish and US TMD centers using research diagnostic criteria for temporomandibular disorders. J Orofac Pain 1996; 10:240-53
304. Yap AU, Dworkin SF, Chua EK, List T, Tan KB, Tan HH: Prevalence of temporomandibular disorder subtypes, psychologic distress, and psychosocial dysfunction in Asian patients. J Orofac Pain 2003; 17:21-8
305. Pinho JC, Caldas FM, Mora MJ, Santana-Penin U: Electromyographic activity in patients with temporomandibular disorders. J Oral Rehabil 2000; 27:985-90
306. Crider AB, Glares AG: A meta-analysis of EMG biofeedback treatment of temporomandibular disorders. J Orofac Pain 1999; 13:29-37
307. Goldstein BH: Temporomandibular disorders: A review of current understanding. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88:379-85
308. Morris FH, Gasteiger EL, Chatfield PO: An electromyographic study of induced and spontaneous muscle cramps. Electroencephalogr Clin Neurophysiol 1957; 9:139-47
309. McGee SR: Muscle cramps. Arch Intern Med 1990; 150:511-8
310. Denny-Brown D; Clinical problems in neuromuscular physiology. Am J Med 1953; 15:368-90
311. McCance RA: Experimental sodium chloride deficiency in man. Proc R Soc Lond Biol 1936; 119:245-68
312. Araki S, Terao A, Matsumoto I, Narazaki T, Kuroiwa Y: Muscle cramps in chronic thyrotoxic myopathy. Arch Neurol 1986; 19:315-20
313. Simons DG, Travell JG, Simons LS: Travell and Simons' Myofascial Pain and Dysfunction: The Trigger Point Manual. Vol I, 2nd edition. Baltimore, Williams & Wilkins, 1999, pp 11-93
314. Gerwin RD, Shannon S, Hong CZ, Hubbard D, Gevirtz R: Interrater reliability in myofascial trigger point examination. Pain 1997; 69:65-73
315. Wolfe F, Simons DG, Fricton J, Bennett RM, Goldenberg DL, Gerwin R, Hathaway D, McCain GA, Russel IJ, Sanders HO, Skootsky SA: The fibromyalgia and myofascial pain syndromes: A preliminary study of tender points and trigger points in persons with fibromyalgia, myofascial pain syndrome and no disease. J Rheumatol 1992; 19:944-51
316. Sola AE, Rodenberger ML, Gettys BB: Incidence of hypersensitive areas in posterior shoulder muscles. Am J Phys Med 1955; 34:585-90
317. Frohlich D, Frohlich R: Piriformis syndrome: A frequent item in the differential diagnosis of lumbogluteal pain. Manuelle Med 1995; 33:7-10
318. Hong CZ, Simons DG: Pathophysiologic and electrophysiologic mechanisms of myofascial trigger points. Arch Phys Med Rehabil 1998; 79:863-72
319. Simons DG, Hong CZ, Simons LS: Prevalence of spontaneous electrical activity at trigger spots and at control sites in rabbit skeletal muscle. J Musculoskeletal Pain 1995; 3:35-48
320. Hubbard DR, Berkoff GM: Myofascial trigger points show spontaneous needle EMG activity. Spine 1993; 18:1803-7
321. Hubbard DR: Chronic and recurrent muscle pain: Pathophysiology and treatment, and review of pharmacologic studies. J Musculoskeletal Pain 1996; 4:123-43
322. Buchthal F, Rosenfalck P: Spontaneous electrical activity of human muscle. Electroencephalogr Clin Neurophysiol 1966; 20:321-36
323. Rivner MH: The neurophysiology of myofascial pain syndrome. Curr Pain Headache Rep 2001; 5:432-40
324. Bohr TW: Problems with myofascial pain syndrome and fibromyalgia syndrome. Neurology 1996; 46:593-7