Fibroblast migration after myocardial infarction is regulated by transient SPARC expression

Journal of Molecular Medicine

Volumn 84, Issue 3, 2006, Pages 241-252

  Wu, Rong Xue ^a   Laser, Martin ^a   Han, Hong ^a   Varadarajulu, Jeeva ^a   Schuh, Kai ^a   Hallhuber, Matthias ^a   Hu, Kai ^a   Ertl, Georg ^a   Hauck, Christof R ^a   Ritter, Oliver ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b University of Würzburg ^*  (Germany)

Author keywords

Cell migration; Extracellular matrix; Myocardial infarction; Tissue remodeling

Indexed keywords

ALPHA INTEGRIN; FIBRONECTIN; OSTEONECTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; FIBROBLAST; HEART INFARCTION; HEART MUSCLE; IMMUNOFLUORESCENCE; MALE; MOUSE; NONHUMAN; OSMOTIC MINIPUMP; PROTEIN EXPRESSION; SCAR FORMATION; UPREGULATION; WOUND HEALING;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; FIBRONECTINS; GENE EXPRESSION REGULATION; INTEGRIN ALPHA CHAINS; INTEGRINS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; OSTEONECTIN; PLATELET-DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; VITRONECTIN;

EID: 33344477904     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-005-0026-0     Document Type: Article

References (36)

1. Shai SY et al (2002) Cardiac myocyte-specific excision of the beta 1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res 90(4):458-464
2. Schellings MW, Pinto YM, Heymans S (2004) Matricellular proteins in the heart: possible role during stress and remodeling. Cardiovasc Res 64(1):24-31
3. Bradshaw AD, Reed MJ, Sage EH (2002) SPARC-null mice exhibit accelerated cutaneous wound closure. J Histochem Cytochem 50(1):1-10
4. Funk SE, Sage EH (1993) Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts. J Cell Physiol 154(1):53-63
5. Komatsubara I et al (2003) Spatially and temporally different expression of osteonectin and osteopontin in the infarct zone of experimentally induced myocardial infarction in rats. Cardiovasc Pathol 12(4):186-194
6. Masson S et al (1998) Remodelling of cardiac extracellular matrix during beta-adrenergic stimulation: upregulation of SPARC in the myocardium of adult rats. J Mol Cell Cardiol 30(8):1505-1514
7. Simkhovich BZ et al (2003) Gene expression profiling - a new approach in the study of myocardial ischemia. Cardiovasc Pathol 12(4):180-185
8. Bornstein P, Sage EH (2002) Matricellular proteins: extracellular modulators of cell function. Curr Opin Cell Biol 14(5):608-616
9. Lane TF, Sage EH (1994) The biology of SPARC, a protein that modulates cell-matrix interactions. FASEB J 8(2):163-173
10. De S et al (2003) Molecular pathway for cancer metastasis to bone. J Biol Chem 278(40):39044-39050
11. Sturm RA et al (2002) Osteonectin/SPARC induction by ectopic beta(3) integrin in human radial growth phase primary melanoma cells. Cancer Res 62(1):226-232
12. Lode HN et al (1999) Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proc Natl Acad Sci USA 96(4):1591-1596
13. DeNardo SJ et al (2000) Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy. Cancer Biother Radiopharm 15(1):71-79
14. Varadarajulu J et al (2005) Targeting of alpha(v) integrins interferes with FAK activation and smooth muscle cell migration and invasion. Biochem Biophys Res Commun 331(2):404-412
15. Burkard N et al (2005) Targeted proteolysis sustains calcineurin activation. Circulation 111(8):1045-1053
16. Hauck CR et al (2001) Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 61(19):7079-7090
17. Stanton LW et al (2000) Altered patterns of gene expression in response to myocardial infarction. Circ Res 86(9):939-945
18. Laser M et al (2000) Integrin activation and focal complex formation in cardiac hypertrophy. J Biol Chem 275(45):35624-35630
19. Ross RS (2002) The extracellular connections: the role of integrins in myocardial remodeling. J Card Fail 8[6 Suppl]:S326-S331
20. Holland PW et al (1987) In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. J Cell Biol 105(1):473-482
21. Sage H et al (1989) SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix. J Cell Biol 109(1):341-356
22. Sage H et al (1989) Distribution of the calcium-binding protein SPARC in tissues of embryonic and adult mice. J Histochem Cytochem 37(6):819-829
23. Reed MJ et al (1993) Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J Histochem Cytochem 41(10):1467-1477
24. Nisato RE et al (2003) Alphav beta 3 and alphav beta 5 integrin antagonists inhibit angiogenesis in vitro. Angiogenesis 6(2):105-119
25. Sage EH, Bornstein P (1991) Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin. J Biol Chem 266(23):14831-14834
26. Wrana JL, Overall CM, Sodek J (1991) Regulation of the expression of a secreted acidic protein rich in cysteine (SPARC) in human fibroblasts by transforming growth factor beta. Comparison of transcriptional and post-transcriptional control with fibronectin and type I collagen. Eur J Biochem 197(2):519-528
27. Zhou H et al (1993) Differential effects of transforming growth factor-beta 1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts. J Cell Physiol 155(1):112-119
28. Reed MJ et al (1994) TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors. J Cell Physiol 158(1):169-179
29. Shiba H et al (1998) Differential effects of various growth factors and cytokines on the syntheses of DNA, type I collagen, laminin, fibronectin, osteonectin/secreted protein, acidic and rich in cysteine (SPARC), and alkaline phosphatase by human pulp cells in culture. J Cell Physiol 174(2):194-205
30. Thompson NL et al (1988) Transforming growth factor beta-1 in acute myocardial infarction in rats. Growth Factors 1(1):91-99
31. Deten A et al (2001) Changes in extracellular matrix and in transforming growth factor beta isoforms after coronary artery ligation in rats. J Mol Cell Cardiol 33(6):1191-1207
32. Francki A et al (2004) SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells. J Cell Biochem 91(5):915-925
33. Schiemann BJ, Neil JR, Schiemann WP (2003) SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system. Mol Biol Cell 14(10):3977-3988
34. Rempel SA et al (2001) SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins. J Neurooncol 53(2):149-160
35. Brekken RA, Sage EH (2000) SPARC, a matricellular protein: at the crossroads of cell-matrix. Matrix Biol 19(7):569-580
36. Basu A et al (2001) Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40). BMC Cell Biol 2(1):15