Blocking intrahepatic deletion of activated CD8+ T cells by an altered peptide ligand

Cellular Immunology

Volumn 238, Issue 1, 2005, Pages 31-37

  Kuniyasu, Yuhshi ^a   Qamar, Amir ^a   Sheikh, Shehzad Zafar ^a   Jhandier, Muhammad Nauman ^a   Hakim, Wyel ^a   Mehal, Wajahat Zafar ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytotoxicity; Deletion; Hepatitis; Immunology; Intrahepatic T cells; Peptides

Indexed keywords

CD8 ANTIGEN; G4 PEPTIDE; LIGAND; PEPTIDE DERIVATIVE; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HEPATITIS; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; APOPTOSIS; CD8-POSITIVE T-LYMPHOCYTES; EGG PROTEINS; FLOW CYTOMETRY; HEPATOCYTES; LIGANDS; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; SPECIFIC PATHOGEN-FREE ORGANISMS; T-LYMPHOCYTES, CYTOTOXIC;

ANIMALIA;

EID: 33344462673     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellimm.2005.12.006     Document Type: Article

References (20)

1. I.N. Crispe Hepatic T cells and liver tolerance Nature Reviews Immunology 3 1 2003 51 62
2. W.Z. Mehal, F. Azzaroli, and I.N. Crispe Immunology of the healthy liver: old questions and new insights Gastroenterology 120 1 2001 250 260
3. + T cells by mouse liver Hepatology 39 4 2004 1017 1027
4. D.R. Green, N. Droin, and M. Pinkoski Activation-induced cell death in T cells Immunological Reviews 193 2003 70 81
5. L. Huang, G. Soldevila, M. Leeker, R.F. Flavell, and I.N. Crispe The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo Immunity 1 9 1994 741 749
6. W.Z. Mehal Intrahepatic T cell survival versus death: which one prevails and why? Journal of Hepatology 39 6 2003 1070 1071
7. + T cells creates double-negative cells in vivo Journal of Immunology 161 4 1998 1686 1693
8. G.T. Belz, J.D. Altman, and P.C. Doherty Characteristics of virus-specific CD8(+) T cells in the liver during the control and resolution phases of influenza pneumonia Proceedings of the National Academy of Sciences of the United States of America 95 23 1998 13812 13817
9. M.K. Maini, and A. Bertoletti How can the cellular immune response control hepatitis B virus replication? Journal of Viral Hepatitis 7 5 2000 321 326
10. C. Neumann-Haefelin, H.E. Blum, F.V. Chisari, and R. Thimme T cell response in hepatitis C virus infection Journal of Clinical Virology 32 2 2005 75 85
11. B. Bielekova, and R. Martin Antigen-specific immunomodulation via altered peptide ligands Journal of Molecular Medicine 79 10 2001 552 565
12. K.A. Hogquist, S.C. Jameson, W.R. Heath, J.L. Howard, M.J. Bevan, and F.R. Carbone T cell receptor antagonist peptides induce positive selection Cell 76 1 1994 17 27
13. D. Haribhai, B. Edwards, M.L. Williams, and C.B. Williams Functional reprogramming of the primary immune response by T cell receptor antagonism Journal of Experimental Medicine 200 11 2004 1371 1382
14. S.R. Burrows, R. Khanna, and D.J. Moss Direct alloreactivity by human cytotoxic T lymphocytes can Be inhibited by altered peptide ligand antagonism Blood 93 3 1999 1020 1024
15. A. Faith, C.A. Akdis, M. Akdis, A. Joss, D. Wymann, and K. Blaser An altered peptide ligand specifically inhibits Th2 cytokine synthesis by abrogating TCR signaling Journal of Immunology 162 3 1999 1836 1842
16. C. Rosette, G. Werlen, M.A. Daniels, P.O. Holman, S.M. Alam, P.J. Travers, N.R. Gascoigne, E. Palmer, and S.C. Jameson The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model Immunity 15 1 2001 59 70
17. S.M. Alam, G.M. Davies, C.M. Lin, T. Zal, W. Nasholds, S.C. Jameson, K.A. Hogquist, N.R. Gascoigne, and P.J. Travers Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands Immunity 10 2 1999 227 237 [Journal Article]
18. + T cell responses to high- and low-affinity TCR interactions Int. Immunol., Advance Access published on April 11 International Immunology (2005).
19. J.Q. Russell, G.J. Morrissette, M. Weidner, C. Vyas, D. Aleman-Hoey, and R.C. Budd Liver damage preferentially results from CD8(+) T cells triggered by high affinity peptide antigens Journal of Experimental Medicine 188 6 1998 1147 1157
20. + T cells by the normal liver Journal of Immunology 163 1999 3202 3210