Epilepsy genetics

Neurologist

Volumn 8, Issue 3, 2002, Pages 133-151

  Winawer, Melodie R ^a  

^a Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

Author keywords

Epilepsy; Familial; Genetic; Seizures

Indexed keywords

ION CHANNEL;

ABSENCE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL RECESSIVE DISORDER; BENIGN CHILDHOOD EPILEPSY; CENTRAL NERVOUS SYSTEM DISEASE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; FAMILIAL DISEASE; FAMILY HISTORY; FAMILY STUDY; FEBRILE CONVULSION; GENETIC COUNSELING; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HERITABILITY; HUMAN; IDIOPATHIC DISEASE; INHERITANCE; MYOCLONUS EPILEPSY; ONSET AGE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SEIZURE; SYNDROME DELINEATION; TWINS;

EID: 0036271585     PISSN: 10747931     EISSN: None     Source Type: Journal    
DOI: 10.1097/00127893-200205000-00001     Document Type: Review

References (118)

1. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984
2. Proposal for revised clinical and electroencephalographic classification of epileptic seizures
3. Proposal for revised classification of epilepsies and epileptic syndromes
4. Genetic epidemiology of epilepsy
5. The sequence of the human genome
6. Mitochondrial genes for generalized epilepsies
7. Genetic diseases associated with epilepsy
8. Epilepsies with single gene inheritance
9. Genetics of inherited epilepsies
10. A second locus for familial generalized epilepsy with febrile seizures pulse maps to chromosome 2q21-q33
11. Risk of seizures among relatives of patients with epilepsy: Families in a defined population
12. Hereditary aspects of epilepsy
13. The genetics of epilepsy
14. On the genetic prognosis of epilepsy
15. Data collection strategies in genetic epidemiology: The Epilepsy Family Study of Columbia University
16. Genetic epidemiology of epilepsy
17. Relations of genetic and environmental factors in the etiology of epilepsy
18. Are generalized and localization-related epilepsies genetically distinct?
19. Seizure risk in offspring of parents with generalized versus partial epilepsy
20. The heredity of epilepsy as told by relatives and twins
21. Epilepsies in twins: Genetics of the major epilepsy syndromes
22. Syndrome-related genetics in generalized epilepsy
23. Occurrence of epilepsies in family members of Indian probands with different epileptic syndromes
24. Concordance of clinical forms of epilepsy in families with several affected members
25. Familial occurrence of epilepsy in children with newly diagnosed multiple seizures: Dutch study of epilepsy in childhood
26. Children with familial cryptogenic epilepsy have a favorable seizure prognosis
27. Genetic Influences on susceptibility to seizures
28. Risk factors for epilepsy
29. Progress in the genetics of partial epilepsy
30. A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy
31. A new locus for autosomal dominant nocturnal frontal lobe epilepsy maps to chromosome 1
32. The nicotinic receptor β2 subunit is mutant in nocturnal frontal lobe epilepsy
33. Autosomal dominant nocturnal frontal-lobe epilepsy: Genetic heterogeneity and evidence for a second locus at 15q24
34. Localization of a gene for partial epilepsy to chromosome 10q
35. Autosomal dominant partial epilepsy with auditory features: Defining the phenotype
36. Autosomal dominant lateral temporal epilepsy: Clinical and genetic study of a large Basque pedigree linked to chromosome 10q
37. Autosomal dominant partial epilepsy with auditory features: Description of a new family
38. Supporting evidence of a gene for partial epilepsy on 10q
39. Familial partial epilepsy with variable foci: A new partial epilepsy syndrome with suggestion of linkage to chromosome 2
40. Mapping of a gene determining familial partial epilepsy with variable foci to chromosome 22q11-q12
41. The relation of focal to diffuse epileptiform EEG discharges in genetic epilepsy
42. Familial occurrence of focal temporal electroencephalographic abnormalities
43. Benign epilepsy of childhood with centrotemporal EEG foci: A genetic study
44. Genetics of the partial epilepsies: A review
45. Centrotemporal spikes in families with rolandic epilepsy: Linkage to chromosome 15q14
46. Linkage mapping of benign familial infantile convulsions (BFIC) to chromsome 19q
47. Linkage of benign familial infantile convulsions to chromosome 16p12-q12 suggests allelism to the infantile convulsions and choreoathetosis syndrome
48. Familial temporal lobe epilepsy: A common disorder identified in twins
49. Familial temporal lobe epilepsy: A clinically heterogeneous syndrome
50. Autosomal dominant rolandic epilepsy and speech dyspraxia: A new syndrome with anticipation
51. A new type of epilepsy: Benign partial epilepsy of childhood with occipital spike-waves
52. Benign occipital epilepsy: A family study
53. Reading epilepsy
54. Mapping and positional cloning of common idiopathic generalized epilepsies: Juvenile myoclonus epilepsy and childhood absence epilepsy
55. Reproducibility and complications in gene searches: Linkage on chromosome 6, heterogeneity, association, and maternal inheritance in juvenile myoclonic epilepsy
56. Evidence for linkage of adolescentonset idiopathic generalized epilepsies to chromosome 8-and genetic heterogeneity
57. Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q
58. Confirmation of linkage between juvenile myoclonic epilepsy locus and the HLA region on chromosome 6
59. Localization of idiopathic generalized epilepsy on chromosome 6p in families of juvenile myoclonic epilepsy patients
60. Mapping of genes predisposing to idiopathic generalized epilepsy
61. Linkage analysis of idiopathic generalized epilepsy (IGE) and marker loci on chromosome 6p in families of patients with juvenile myoclonic epilepsy: No evidence for an epilepsy locus in the HLA region
62. No evidence for a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q
63. Replication analysis of a putative susceptibility locus (EG1) for idiopathic generalized epilepsy on chromosome 8q24
64. Genome search for susceptibility loci of common idiopathic generalized epilepsies
65. Absence epilepsies
66. Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4 Hz spike and multispike-slow wave complexes: Linkage to chromosome 8q24
67. Long-term prognosis of typical childhood absence epilepsy: Remission or progression to juvenile myoclonic epilepsy
68. Generalized epilepsy with febrile seizures plus: A common childhood-onset genetic epilepsy syndrome
69. Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel 36 1 subunit gene SCN1B
70. A new locus for generalized epilepsy with febrile seizures plus maps to chromosome 2
71. Identification of a new locus for generalized epilepsy with febrile seizures plus (GEFS+) on chromosome 2q24-q33
72. A second locus for familial generalized epilepsy with febrile seizures plus maps to chromosome 2q21-q33
73. Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2
74. Neonate with benign familial neonatal convulsions: Recorded generalized and focal seizures
75. A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns
76. A potassium channel mutation in neonatal human epilepsy
77. A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family
78. Genetic localization of the familial adult myoclonic epilepsy (FAME) gene to chromosome 8q24
79. Mapping of a locus for familial autosomal recessive idiopathic myoclonic epilepsy of infancy to chromosome 16p13
80. Consensus development conference on febrile seizures, National Institutes of Health, May 19-21, 1980
81. Suggestion of a major gene for familial febrile convulsions mapping to 8q13-21
82. Evidence for a novel gene for familial febrile convulsions, FEB2, linked to chromosome 19p in an extended family from the Midwest
83. Significant evidence for linkage of febrile seizures to chromosome 5q14-q15
84. Searching for genetic determinants in the new millennium
85. Coding and noncoding variation of the human calcium-channel 36-4 subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia
86. Ion channels and the genetic contribution to epilepsy
87. Ion channels and epilepsy in man and mouse
88. Genetics, an alternative way to discover, characterize, and understand ion channels
89. Animal models of inherited epilepsy
90. The use and role of EEG in the genetic analysis of epilepsy
91. EEG patterns and genetics
92. Genetic aspects of the EEG: An investigation into the within-pair similarity of monozygotic and dizygotic twins with a new method of analysis
93. The heredity of epilepsy as told by relatives and twins
94. Reliable computer-assisted classification of the EEG: EEG variants in index cases and their first degree relatives
95. Untersuchungen zur genetik der Beta-Wellen im EEG des Menschen
96. Grundlegenen und bedeutung genetisch bedingter variabilitat des normalen menschlichen EEG
97. Charakterisierung erblicher EEG-varianten. Mit hilfe der amplituden-intervall-analyse I
98. Charakterisierung erblicher EEG-varianten. Mit hilfe der amplituden-intervall-analyse II
99. On the genetics of EEG-anomalies in childhood III. Spikes and Waves
100. On the genetics of EEG-anomalies in childhood IV. Photoconvulsive reaction
101. EEG findings in children of epileptic parents
102. Handbook of Electroencephalogr
103. Genetic factors in the epilepsies
104. Genetic counseling
105. Effectiveness of multiple EEGs in supporting the diagnosis of epilepsy: An operational curve
106. Maturational and biorhythmic changes in the electroencephalogram
107. The development of the electroencephalogram in normal children from the age of 1 through 15 years. Paroxysmal activity
108. Disappearance and migration of epileptic foci in childhood
109. Multifactorial inheritance of generalized and focal epilepsy
110. Syndrome-related genetics in generalized epilepsy
111. Higher risk of seizures in offspring of mothers than of fathers with epilepsy
112. The risk of seizure disorders among relatives of children with febrile convulsions
113. Mutations in LGI-1 cause autosomal dominant partial epilepsy with auditory features