Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 7, 2006, Pages 2013-2016

  Zhang, Chuan Xin ^a   Ge, Ze Mei ^a   Cheng, Tie Ming ^a   Li, Run Tao ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Analgesic activity; Highly sterically hindered secondary amine analogues of pyridylmethylamine; Nicotinic cholinergic receptor; Synthesis

Indexed keywords

5 (2 AZETIDINYLMETHOXY) 2 CHLOROPYRIDINE; AMINE; PYRIDINE DERIVATIVE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; AZETIDINES; ISOMERISM; PYRIDINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 33144490301     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.12.073     Document Type: Article

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