Solid-phase synthesis of 1,3,4-oxadiazoline-5-thione derivatives from resin-bound acylhydrazines

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 7, 2006, Pages 1828-1830

  Liu, Zhanxiang ^a   Zhao, Jinlong ^a   Huang, Xian ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acylhydrazines; Solid phase synthesis; Substituted 1,3,4 oxadiazoles

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; ANTIFUNGAL AGENT; ANTIINFLAMMATORY AGENT; HYDRAZINE DERIVATIVE; RESIN;

ARTICLE; CHEMICAL PROCEDURES; CHEMICAL REACTION; DRUG SYNTHESIS; SOLID;

HYDRAZINES; OXADIAZOLES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 33144463755     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.002     Document Type: Article

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24. 2, the acylhydrazine resin 3 (loading = 1.59 mmol/g, based on N microanalysis) was obtained (Caution! HMPA has relative toxicity).
25. 2S, C, 49.47; H, 3.11; N, 14.42; O, 16.48; S, 16.51. Found: C, 49.09; H, 3.26; N, 14.28.
26. The other analytical data of compounds 6b-6i were listed in Supplementary material which is available online.