Design and synthesis of 4H-3-(2-phenoxy)phenyl-1,2,4-triazole derivatives as benzodiazepine receptor agonists

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 5, 2003, Pages 769-773

  Akbarzadeh, Tahmineh ^a   Tabatabai, Sayyed A ^b   Khoshnoud, Mohammad J ^b   Shafaghi, Bijan ^b   Shafiee, Abbas ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 5 ETHOXY 4H 1,2,4 TRIAZOLE; 3 AMINO 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 4H 1,2,4 TRIAZOLE; 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 2 AMINO 1,3,4 OXADIAZOLE; 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 ONE; 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 3 METHYLSULFONYL 4H 1,2,4 TRIAZOLE; 5 [4 CHLORO 2 (2 CHLOROPHENOXY)PHENYL] 3 METHYLTHIO 4H 1,2,4 THIAZOLE; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; CHLORINE DERIVATIVE; DIAZEPAM; ESTAZOLAM; PENTETRAZOLE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHLORINATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DESIGN; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; EXPERIMENTAL MODEL; MALE; MOUSE; NONHUMAN; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICONVULSANTS; CONVULSANTS; DIAZEPAM; DRUG DESIGN; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUSCULOSKELETAL EQUILIBRIUM; PENTYLENETETRAZOLE; RECEPTORS, GABA-A; SEIZURES; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 0037355067     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00469-8     Document Type: Article

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