Dual effect of KrasD12 knockdown on tumorigenesis: Increased immune-mediated tumor clearance and abrogation of tumor malignancy

Oncogene

Volumn 24, Issue 56, 2005, Pages 8338-8342

  Smakman, Niels ^a   Veenendaal, Liesbeth M ^a   Van Diest, Paul ^a   Bos, Rinke ^b   Offringa, Rienk ^b   Borel Rinkes, Inne H M ^a   Kranenburg, Onno ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Colorectal; Immune evasion; Interleukin 18; Malignancy; Ras

Indexed keywords

INTERLEUKIN 18; K RAS D12 PROTEIN; K RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CANCER REGRESSION; CARCINOGENESIS; CELL TRANSFORMATION; COLORECTAL CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOST; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNE SYSTEM; IN VITRO STUDY; KNOCKOUT GENE; MORBIDITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RNA INTERFERENCE; SUBCUTANEOUS TISSUE TUMOR;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; GENE DELETION; HUMANS; INTERLEUKIN-18; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS P21(RAS); RNA INTERFERENCE;

ANIMALIA; MURINAE;

EID: 32844467282     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208995     Document Type: Article

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