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Volumn 11, Issue 2 P.1591-2006, 2006, Pages 1774-1793

Gene chromosomal organization and expression in cultured human neurons exposed to cocaine and HIV-1 proteins gp120 and tat: Drug abuse and NeuroAIDS

(17)  Shapshak, Paul a   Duncan, Robert a   Nath, Avindra b   Turchan, Jadwiga c   Kangueane, Pandjassarame d   Rodriguez, Hector a   Duran, E Margarita a   Ziegler, Fabians a   Amaro, Eric a   Lewis, Apple a   Rodriguez, Alejandro a   Minagar, Alireza e,f   Davis, Wade g   Seth, Raman h,i   Elkomy, Fatten F i   Chiappelli, Francesco j   Kazic, Toni h,i  


Author keywords

Affymetrix; AIDS; Ariadne Pathways Assist; Bioinformatics; Chromosome Damage; Cocaine; Coerced Transcription; Culture; Encephalitis; Gene Expression; gp120; HIV Associated Dementia (HAD); HIV 1; Human; Microarray; Neuron; Tat; Transcription Isolation

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 32844463565     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1922     Document Type: Article
Times cited : (5)

References (95)
  • 2
    • 32844464596 scopus 로고    scopus 로고
    • Bureau of Justice Statistics. Drug and Crime Facts. http://www.ojp.usdoj. gov/bjs/ (2005)
    • (2005) Drug and Crime Facts
  • 3
    • 32844462626 scopus 로고    scopus 로고
    • Research Report Series
    • National Institute on Drug Abuse. Cocaine Abuse and Addiction. Research Report Series, (1998)
    • (1998) Cocaine Abuse and Addiction
  • 4
    • 0023866331 scopus 로고
    • Early penetration of the blood-brain barrier by HTLV-III/LAV
    • Resnick, L., Berger, J. R., Shapshak, P., and Tourtellotte, W. W.: Early penetration of the blood- brain barrier by HTLV-III/LAV. Neurology 8, 9-15 (1988)
    • (1988) Neurology , vol.8 , pp. 9-15
    • Resnick, L.1    Berger, J.R.2    Shapshak, P.3    Tourtellotte, W.W.4
  • 5
    • 0028328420 scopus 로고
    • Cerebrospinal fluid p24 antigen levels and intrathecal immunoglobulin G synthesis are associated with cognitive disease severity in HIV-1
    • Singer, E. J., Syndulko, K., Fahy-Chandon, B. N., Shapshak, P., Resnick, L., Schmid, P., Conrad, A. J., and Tourtellotte W. W.: Cerebrospinal fluid p24 antigen levels and intrathecal immunoglobulin G synthesis are associated with cognitive disease severity in HIV-1. AIDS 8, 197-204 (1994)
    • (1994) AIDS , vol.8 , pp. 197-204
    • Singer, E.J.1    Syndulko, K.2    Fahy-Chandon, B.N.3    Shapshak, P.4    Resnick, L.5    Schmid, P.6    Conrad, A.J.7    Tourtellotte, W.W.8
  • 7
    • 0025008853 scopus 로고
    • High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients
    • Pang S, Koyanagi Y, Miles S, Wiley C, Vinters HV, and Chen I. S. Y.: High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 85-89, (1990)
    • (1990) Nature , pp. 85-89
    • Pang, S.1    Koyanagi, Y.2    Miles, S.3    Wiley, C.4    Vinters, H.V.5    Chen, I.S.Y.6
  • 11
    • 0034723366 scopus 로고    scopus 로고
    • HIV infection and dementia
    • Gartner, S.: HIV Infection and Dementia. Science, 287, 602-604, (2000)
    • (2000) Science , vol.287 , pp. 602-604
    • Gartner, S.1
  • 12
    • 0036096739 scopus 로고    scopus 로고
    • Insights into the role of immune activation in HIV neuropathogenesis
    • Gartner, S. and Liu, Y.: Insights into the role of immune activation in HIV neuropathogenesis. J Neurovirol 8, 69-75, (2002)
    • (2002) J Neurovirol , vol.8 , pp. 69-75
    • Gartner, S.1    Liu, Y.2
  • 13
    • 0028356005 scopus 로고
    • In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-a RNA in the central nervous system
    • Nuovo, G. J., Gallery, F., MacConnell, P., and Braun, A.: In Situ Detection of Polymerase Chain Reaction-Amplified HIV-1 Nucleic Acids and Tumor Necrosis Factor-a RNA in the Central Nervous System. Am J Path 144, 659-665 (1994)
    • (1994) Am J Path , vol.144 , pp. 659-665
    • Nuovo, G.J.1    Gallery, F.2    MacConnell, P.3    Braun, A.4
  • 14
    • 0028226662 scopus 로고
    • HIV-1 infection of subcortical astrocytes in the pediatric central nervous system
    • Tornatore, C., Chandra, R., Berger, J. R. and Major, E. O.: HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurol 44, 481-487 (1994)
    • (1994) Neurol , vol.44 , pp. 481-487
    • Tornatore, C.1    Chandra, R.2    Berger, J.R.3    Major, E.O.4
  • 15
    • 0030011404 scopus 로고    scopus 로고
    • Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: Identification by the combination of in situ polymerase chain reaction and immunohistochemistry
    • Bagasra, O., Lavi, E., Bobroski, L., Khalili, K., Pestaner, J. P., Tawadros, R., and Pomerantz, R. J.: Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry. AIDS 10, 573-585 (1996)
    • (1996) AIDS , vol.10 , pp. 573-585
    • Bagasra, O.1    Lavi, E.2    Bobroski, L.3    Khalili, K.4    Pestaner, J.P.5    Tawadros, R.6    Pomerantz, R.J.7
  • 17
    • 0026955972 scopus 로고
    • The use of combined in situ hybridization and immunocytochemistry to identify HIV-1 infected cells in brain tissue
    • Shapshak, P., Yoshioka, M., Sun, N. C. J., and Schiller, P.: The use of combined in situ hybridization and immunocytochemistry to identify HIV-1 infected cells in brain tissue. Modern Pathology 5, 649-654 (1992)
    • (1992) Modern Pathology , vol.5 , pp. 649-654
    • Shapshak, P.1    Yoshioka, M.2    Sun, N.C.J.3    Schiller, P.4
  • 19
    • 0031764403 scopus 로고    scopus 로고
    • HIV encephalitis, proviral load, and dementia in drug users and homosexuals with AIDS. Effects of neocortical involvement
    • Bell, J. E., Brettle, R. P., Chiswick, A., and Simmonds, P.: HIV encephalitis, proviral load, and dementia in drug users and homosexuals with AIDS. Effects of neocortical involvement. Brain 121, 2043-2052 (1998)
    • (1998) Brain , vol.121 , pp. 2043-2052
    • Bell, J.E.1    Brettle, R.P.2    Chiswick, A.3    Simmonds, P.4
  • 21
    • 0036948724 scopus 로고    scopus 로고
    • Neural immunity: Friend or foe?
    • Gendelman, H. E.: Neural immunity: Friend or foe? J Neurovirol 8, 474-479 (2002)
    • (2002) J Neurovirol , vol.8 , pp. 474-479
    • Gendelman, H.E.1
  • 23
    • 0032930241 scopus 로고    scopus 로고
    • Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity
    • Adamson, D. C., Kopnisky, K. L., Dawson, T. M., Dawson, V. L.: Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity. J Neurosci 19, 64-71 (1999)
    • (1999) J Neurosci , vol.19 , pp. 64-71
    • Adamson, D.C.1    Kopnisky, K.L.2    Dawson, T.M.3    Dawson, V.L.4
  • 24
    • 0028909868 scopus 로고
    • Dementia associated with the acquired immunodeficiency syndrome
    • Lipton, S. A. and Gendelman, H. E.: Dementia Associated with the Acquired Immunodeficiency Syndrome. N Eng J Med 332, 934-940 (1995)
    • (1995) N Eng J Med , vol.332 , pp. 934-940
    • Lipton, S.A.1    Gendelman, H.E.2
  • 25
    • 0027716965 scopus 로고
    • A mechanism of Quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate
    • Heyes, M. P., Saito, K., Major, E. O., Milstien, S., Markey, S. P., and Vickers J. H.: A mechanism of Quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate. Brain 116(Pt 6), 1425-1450 (1993)
    • (1993) Brain , vol.116 , Issue.PART 6 , pp. 1425-1450
    • Heyes, M.P.1    Saito, K.2    Major, E.O.3    Milstien, S.4    Markey, S.P.5    Vickers, J.H.6
  • 26
    • 0036947132 scopus 로고    scopus 로고
    • Increased density of Neurons containing NADPH diaphorase/nitric oxide synthase in the cerebral cortex of patients with HIV-1 infection & drug abuse
    • Kuljis, R. O., Shapshak, P., Rodriguez de la Vega, P., and Petito, C.: Increased density of Neurons containing NADPH diaphorase/nitric oxide synthase in the cerebral cortex of patients with HIV-1 infection & drug abuse. J NeuroAIDS 2, 19-36 (2003)
    • (2003) J NeuroAIDS , vol.2 , pp. 19-36
    • Kuljis, R.O.1    Shapshak, P.2    Rodriguez De La Vega, P.3    Petito, C.4
  • 29
    • 0004306672 scopus 로고    scopus 로고
    • Chemokines and apoptosis in HIV Dementia
    • Gonzales-Scarano, F.: Chemokines and apoptosis in HIV Dementia. J Neurovirol 6, 242-244, (2000)
    • (2000) J Neurovirol , vol.6 , pp. 242-244
    • Gonzales-Scarano, F.1
  • 32
    • 0031809772 scopus 로고    scopus 로고
    • Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIVmac variant
    • Strelow, L. I., Watry, D. D., Fox, H. S., and Nelson, J. A.: Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIVmac variant. J Neurovirol, 4, 269-80 (1998)
    • (1998) J Neurovirol , vol.4 , pp. 269-280
    • Strelow, L.I.1    Watry, D.D.2    Fox, H.S.3    Nelson, J.A.4
  • 33
    • 0032874020 scopus 로고    scopus 로고
    • Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy. Protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj
    • Hodge, S., de Rosayro, J., Glenn, A., Ojukwu I. C., Dewhurst, S., McClure, H. M., Bischofberger, N., Anderson, D., Klumpp, S. A., and Novembre, F. J.: Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy. Protects against Development of Acute Disease Induced by the Unique Simian Immunodeficiency Virus SIVsmmPBj. J Virol 73, 8630-8639 (1999)
    • (1999) J Virol , vol.73 , pp. 8630-8639
    • Hodge, S.1    De Rosayro, J.2    Glenn, A.3    Ojukwu, I.C.4    Dewhurst, S.5    McClure, H.M.6    Bischofberger, N.7    Anderson, D.8    Klumpp, S.A.9    Novembre, F.J.10
  • 35
    • 0029792878 scopus 로고    scopus 로고
    • Stereological analysis of cerebral atrophy in human immunodeficiency virus-associated dementia
    • Subbiah, P., Mouton, P., Fedor, H., McArthur, J. C., and Glass, J. D.: Stereological Analysis of Cerebral Atrophy in Human Immunodeficiency Virus-associated Dementia. J Neuropath ExpNeurol 55, 1032-1037 (1996)
    • (1996) J Neuropath ExpNeurol , vol.55 , pp. 1032-1037
    • Subbiah, P.1    Mouton, P.2    Fedor, H.3    McArthur, J.C.4    Glass, J.D.5
  • 37
    • 0028024080 scopus 로고
    • Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
    • Wiley, C. A. and Achim, C.: Human Immunodeficiency Virus Encephalitis is the Pathological Correlate of Dementia in Acquired Immunodeficiency Syndrome. Ann Neurol 36, 673-676 (1994)
    • (1994) Ann Neurol , vol.36 , pp. 673-676
    • Wiley, C.A.1    Achim, C.2
  • 38
    • 0024438303 scopus 로고
    • Echoencephalographic findings in neonates associated with maternal cocaine and methamphetamine use: Incidence and clinical correlates
    • Dixon, S. D. and Bejar, R.: Echoencephalographic findings in neonates associated with maternal cocaine and methamphetamine use: incidence and clinical correlates. J Pediatr 115(5 Pt 1), 770-778 (1989)
    • (1989) J Pediatr , vol.115 , Issue.5 PART 1 , pp. 770-778
    • Dixon, S.D.1    Bejar, R.2
  • 43
    • 0029877341 scopus 로고    scopus 로고
    • Increased NADPH-diaphorase reactivity and cytokine expression in dorsal root ganglia in AIDS
    • Nagano, I., Shapshak, P., Yoshioka, M., Xin, K. Q., Nakamura, S., and Bradley, W. G.: Increased NADPH-diaphorase reactivity and cytokine expression in dorsal root ganglia in AIDS. J Neuro Sci 136, 117-128 (1996)
    • (1996) J Neuro Sci , vol.136 , pp. 117-128
    • Nagano, I.1    Shapshak, P.2    Yoshioka, M.3    Xin, K.Q.4    Nakamura, S.5    Bradley, W.G.6
  • 44
    • 0026643346 scopus 로고
    • Cytokine expression in the brain during the acquired immunodeficiency syndrome
    • Tyor, W. R., Glass, J. D., Griffin, J. W., Becker, P. S., McArthur, J. C., Bezman L, et al. Cytokine expression in the brain during the acquired immunodeficiency syndrome. Ann Neurol 31, 349-360 (1992)
    • (1992) Ann Neurol , vol.31 , pp. 349-360
    • Tyor, W.R.1    Glass, J.D.2    Griffin, J.W.3    Becker, P.S.4    McArthur, J.C.5    Bezman, L.6
  • 45
    • 0032923635 scopus 로고    scopus 로고
    • Do alcohol and cocaine abuse alter the course of HIV-associated dementia complex?
    • Tyor, W. R., and Middaugh, L. D.: Do alcohol and cocaine abuse alter the course of HIV-associated dementia complex? J Leukoc Biol 65, 475-479 (1999)
    • (1999) J Leukoc Biol , vol.65 , pp. 475-479
    • Tyor, W.R.1    Middaugh, L.D.2
  • 47
    • 0023181635 scopus 로고
    • Cocaine detection during toxicology screening of a university medical center patient population
    • Bailey, D. N.: Cocaine detection during toxicology screening of a university medical center patient population. J Toxicol Clin Toxicol 25(1-2), 71-79 (1987)
    • (1987) J Toxicol Clin Toxicol , vol.25 , Issue.1-2 , pp. 71-79
    • Bailey, D.N.1
  • 48
    • 0023753947 scopus 로고
    • Characterization of "reverse tolerance" to amphetamine-induced locomotor stimulation in mice
    • Chaudhry, I. A., Turkanis, S. A. and Karler, R.: Characterization of "reverse tolerance" to amphetamine-induced locomotor stimulation in mice. Neuropharmacol 27, 777-781 (1988)
    • (1988) Neuropharmacol , vol.27 , pp. 777-781
    • Chaudhry, I.A.1    Turkanis, S.A.2    Karler, R.3
  • 49
    • 0030791540 scopus 로고    scopus 로고
    • Modulation of cocaine- and methamphetamine-induced behavioral sensitization by inhibition of brain nitric oxide synthase
    • Itzhak, Y.: Modulation of Cocaine- and Methamphetamine-Induced Behavioral Sensitization by Inhibition of Brain Nitric Oxide Synthase. J Pharmacol Exp Therap 282, 521-527 (1997)
    • (1997) J Pharmacol Exp Therap , vol.282 , pp. 521-527
    • Itzhak, Y.1
  • 50
    • 12144256218 scopus 로고    scopus 로고
    • The role of mitochondrial alterations in the combined toxic effects of HIV tat protein and methamphetamine on Calbindin-positive neurons
    • Langford, D., Grigorian, A., Hurford, R., Crews A. A., and Masliah, E.: The role of mitochondrial alterations in the combined toxic effects of HIV tat protein and methamphetamine on Calbindin-positive neurons. J Neurovirol 10, 327-337 (2004)
    • (2004) J Neurovirol , vol.10 , pp. 327-337
    • Langford, D.1    Grigorian, A.2    Hurford, R.3    Crews, A.A.4    Masliah, E.5
  • 51
    • 33846426962 scopus 로고    scopus 로고
    • th Annual Scientific meeting of the CPDD
    • th Annual Scientific meeting of the CPDD, NIDA Monograph Series Volume 185, 82-99 (2005)
    • (2005) NIDA Monograph Series , vol.185 , pp. 82-99
    • Mello, N.K.1    Marian, W.2
  • 52
    • 0025278342 scopus 로고
    • HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists
    • Dreyer EB et al, HIV-1 coat protein neurotoxicity prevented by Calcium channel antagonists, Science 248, 364-367 (1990)
    • (1990) Science , vol.248 , pp. 364-367
    • Dreyer, E.B.1
  • 53
    • 0026755602 scopus 로고
    • Memantine prevents HIV coat protein-induced neuronal injury in vitro
    • Lipton, L.: Memantine prevents HIV coat protein-induced neuronal injury in vitro. Neurology 42, 1403-1405 (1992)
    • (1992) Neurology , vol.42 , pp. 1403-1405
    • Lipton, L.1
  • 54
    • 0033951751 scopus 로고    scopus 로고
    • Synergistic neurotoxicity by HIV proteins tat and gp120: Protection by memantine
    • Nath, A., Haughey, N. J., Jones, M., Anderson, C., Bell, J. E., and Geiger, J. D.: Synergistic neurotoxicity by HIV proteins tat and gp120: protection by memantine. Ann Neurol 7, 186-194 (2000)
    • (2000) Ann Neurol , vol.7 , pp. 186-194
    • Nath, A.1    Haughey, N.J.2    Jones, M.3    Anderson, C.4    Bell, J.E.5    Geiger, J.D.6
  • 55
    • 0028981001 scopus 로고
    • Calbindin D28K-containing neurons, and not HSP70-expressing neurons, are more resistant to HIV-1 envelope (gp120) toxicity in cortical cell Cultures
    • Diop, A. G., Lesort, M., Esclaire, F., Dumas, M., and Hugon, J.: Calbindin D28K-containing neurons, and not HSP70-expressing neurons, are more resistant to HIV-1 envelope (gp120) toxicity in cortical cell Cultures. J Neurosci Res 42, 252-258 (1995)
    • (1995) J Neurosci Res , vol.42 , pp. 252-258
    • Diop, A.G.1    Lesort, M.2    Esclaire, F.3    Dumas, M.4    Hugon, J.5
  • 56
    • 0032838584 scopus 로고    scopus 로고
    • Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures
    • Howard, S. A.: Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures. Exp Neurol 158, 164-170 (1999)
    • (1999) Exp Neurol , vol.158 , pp. 164-170
    • Howard, S.A.1
  • 58
    • 0035882439 scopus 로고    scopus 로고
    • Ethanol exposure inhibits the cytotoxic effect induced by gp120 in CHP100 human neuroblastoma cells
    • Navarra, M.: Ethanol exposure inhibits the cytotoxic effect induced by gp120 in CHP100 human neuroblastoma cells. J Neurosci Res 65, 354-361 (2001)
    • (2001) J Neurosci Res , vol.65 , pp. 354-361
    • Navarra, M.1
  • 60
    • 0027158796 scopus 로고
    • Cocaine cytotoxicity in serum-free environment: C6 glioma cell culture
    • Gu J, Yassini, P., Goldberg, G., Zhu, W., Konat, G. W., Wiggins, R. C.: Cocaine cytotoxicity in serum-free environment: C6 glioma cell culture. Neurotoxicol 14, 19-22 (1993)
    • (1993) Neurotoxicol , vol.14 , pp. 19-22
    • Gu, J.1    Yassini, P.2    Goldberg, G.3    Zhu, W.4    Konat, G.W.5    Wiggins, R.C.6
  • 61
    • 0035010931 scopus 로고    scopus 로고
    • Role of 14-3-3ε, c-Myc/Max, and Akt phosphorylation in HIV-1 gp120-induced mesangial cell proliferation
    • Kapasi, A. A., Fan, S., Singhal, P. C.: Role of 14-3-3ε, c-Myc/Max, and Akt phosphorylation in HIV-1 gp120-induced mesangial cell proliferation. Am J Physiol Renal Physiol 280, 333-342 (2001)
    • (2001) Am J Physiol Renal Physiol , vol.280 , pp. 333-342
    • Kapasi, A.A.1    Fan, S.2    Singhal, P.C.3
  • 62
  • 66
    • 0030068995 scopus 로고    scopus 로고
    • Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic
    • Nath, A., Psooy, K., Martin, C., Knudsen, B., Magnuson, D. S., Haughey, N., Geiger, J. D.: Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J Virol 70, 1475-1480 (1996)
    • (1996) J Virol , vol.70 , pp. 1475-1480
    • Nath, A.1    Psooy, K.2    Martin, C.3    Knudsen, B.4    Magnuson, D.S.5    Haughey, N.6    Geiger, J.D.7
  • 67
    • 0031052029 scopus 로고    scopus 로고
    • Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells
    • Ma, M., and Nath, A.: Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. J Virol 71, 2495-2499 (1997)
    • (1997) J Virol , vol.71 , pp. 2495-2499
    • Ma, M.1    Nath, A.2
  • 78
    • 0037278924 scopus 로고    scopus 로고
    • Treatment of microarray experiments as split-plot designs
    • Emptage, M. R., Hudson-curtis, B., and Sen, K.: Treatment of microarray experiments as split-plot designs. J Biopharm Stat 13, 159-178 (2003)
    • (2003) J Biopharm Stat , vol.13 , pp. 159-178
    • Emptage, M.R.1    Hudson-Curtis, B.2    Sen, K.3
  • 79
    • 0032741507 scopus 로고    scopus 로고
    • Common binding sites for □-Amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortex
    • Lindahl, B., Westling, C., Giménez-Gallego, G., Lindahl, U., and Salmivirta, M.: Common binding sites for □-Amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortex. J Biol Chem 274, 30631-30635 (1999)
    • (1999) J Biol Chem , vol.274 , pp. 30631-30635
    • Lindahl, B.1    Westling, C.2    Giménez-Gallego, G.3    Lindahl, U.4    Salmivirta, M.5
  • 83
    • 0033151570 scopus 로고    scopus 로고
    • Presenilin-1 facilitates the constitutive turnover of beta-catenin: Differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin signaling pathway
    • Kang, D. E., Soriano, S., Frosch, M. P., Collins, T., Naruse, S., Sisodia, S. S., Leibowitz, G., Levine, F., and Koo, E. H.: Presenilin-1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin signaling pathway. J Neurosci 19(11):4229-4237 (1999)
    • (1999) J Neurosci , vol.19 , Issue.11 , pp. 4229-4237
    • Kang, D.E.1    Soriano, S.2    Frosch, M.P.3    Collins, T.4    Naruse, S.5    Sisodia, S.S.6    Leibowitz, G.7    Levine, F.8    Koo, E.H.9
  • 84
    • 0342327346 scopus 로고    scopus 로고
    • Cadherins: Catenins and APC protein: Interplay between cytoskeletal complexes and signaling pathways
    • Barth, A. I., Nathke, I. S., and Nelson, W. J. Cadherins.: Catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr Opin Cell Biol 9, 683-90 (1997)
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 683-690
    • Barth, A.I.1    Nathke, I.S.2    Nelson, W.J.3
  • 85
    • 0032518695 scopus 로고    scopus 로고
    • Signal transduction by the WNT family of ligands
    • Dale, T. C. Signal transduction by the WNT family of ligands. Biochem J 329 (Pt 2), 209-223 (1998)
    • (1998) Biochem J , vol.329 , Issue.PART 2 , pp. 209-223
    • Dale, T.C.1
  • 86
    • 0031039650 scopus 로고    scopus 로고
    • Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin-1
    • Irving, N. G., and Miller, C. C. J.: Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin-1. Neurosci Lett 222, 71-74 (1997)
    • (1997) Neurosci Lett , vol.222 , pp. 71-74
    • Irving, N.G.1    Miller, C.C.J.2
  • 90
    • 11244277000 scopus 로고    scopus 로고
    • Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment
    • Schurov, I. L., Handford, E. J., Brandon, N. J. and Whiting P. J.: Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment Molec Psychiat 9, 1100-1110 (2004)
    • (2004) Molec Psychiat , vol.9 , pp. 1100-1110
    • Schurov, I.L.1    Handford, E.J.2    Brandon, N.J.3    Whiting, P.J.4
  • 92
    • 13444259476 scopus 로고    scopus 로고
    • The tetraspanin web modulates immune-signaling complexes
    • Levy, S., and Tsipi, S.: The Tetraspanin Web Modulates Immune-signaling complexes. Nature 5, 136-148 (2005)
    • (2005) Nature , vol.5 , pp. 136-148
    • Levy, S.1    Tsipi, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.