Angiotensin II activates extracellular signal regulated kinases via protein kinase C and epidermal growth factor receptor in breast cancer cells

Journal of Cellular Physiology

Volumn 196, Issue 2, 2003, Pages 370-377

  Greco, S ^a   Muscella, A ^a   Elia, M G ^a   Salvatore, P ^b   Storelli, C ^a   Mazzotta, A ^b   Manca, C ^b   Marsigliante, Santo ^a  

^a UNIVERSITY OF SALENTO   (Italy)

^b AO Vito Fazzi   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; BREAST CANCER; CALCIUM CELL LEVEL; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOGENICITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANGIOTENSIN II; BREAST NEOPLASMS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; ISOENZYMES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MITOGENS; PROTEIN KINASE C; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

EID: 0037784053     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10313     Document Type: Article

References (46)

1. Acevedo-Duncan M, Patel R, Whelan S, Bicaku E. 2002. Human glioma PKC-ι and PKC-βII phosphorylate cyclin-dependent kinase activating kinase during the cell cycle. Cell Prolif 35:23-36.
2. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270:27489-27494.
3. Berk BC. 1999. Angiotensin II signal transduction in vascular smooth muscle: Pathways activated by specific tyrosine kinases. J Am Soc Nephrol 10:62-68.
4. Berk BC, Corson MA. 1997. Angiotensin II signal transduction in vascular smooth muscle: Role of tyrosine kinases. Circ Res 80:607-616.
5. Berry C, Touyz R, Dominiczak AF, Webb RC, Johns DG. 2001. Angiotensin receptors: Signaling, vascular pathophysiology, and interactions with ceramide. Am J Physiol Heart Circ Physiol 281:2337-2365.
6. Cano E, Mahadevan LC. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20:117-122.
7. Clegg RA, Gordge PC, Miller WR. 1999. Expression of enzymes of covalent protein modification during regulated and dysregulated proliferation of mammary epithelial cells: PKA, PKC and NMT. Advan Enzyme Regul 39:175-203.
8. De Paepe B, Verstraeten VL, De Potter CR, Vakaet LA, Bullock GR. 2001. Growth stimulatory angiotensin II type-1 receptor is upregulated in breast hyperplasia and in situ carcinoma but not in invasive carcinoma. Histochem Cell Biol 116:247-254.
9. Dubey RK, Roy A, Overbeck HW. 1992. Culture of renal arteriolar smooth muscle cells. Mitogenic responses to angiotensin II. Circ Res 71:1143-1152.
10. Eguchi S, Inagami T. 2000. Signal transduction of angiotensin II type I receptor through receptor tyrosine kinase. Regul Peptides 91:13-20.
11. Eguchi S, Matsumoto T, Motley ED, Utsunomiya H, Inagami T. 1996. Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. J Biol Chem 271:14169-14175.
12. Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, Marumo F, Inagami T. 1998. Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273:8890-8896.
13. Eguchi S, Iwasaki Y, Hirata Y, Frank GD, Motley ED, Yamakawa T, Numaguchi K, Inagami T. 1999. Epidermal growth factor receptor is indispensable for c-fos expression and protein synthesis by angiotensin II. Eur J Pharmacol 376:203-206.
14. Fischer TA, Singh K, O'Hara DS, Kaye DM, Kelly RA. 1998. Role of AT1 and AT2 receptors in regulation of MAPKs and MKP-1 by Ang II in adult cardiac myocytes. Am J Physiol Heart Circ Physiol 275:906-916.
15. Greco S, Elia MG, Muscella A, Storelli C, Marsigliante S. 2002a. AT1 angiotensin II receptor mediates intracellular calcium mobilization in normal and cancerous breast cells in primary culture. Cell Calcium 32:1-10.
16. Greco S, Muscella A, Elia MG, Salvatore P, Storelli C, Marsigliante S. 2002b. Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells. J Endocrinol 174:205-214.
17. Gutkind JS. 1998. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J Biol Chem 273:1839-1842.
18. Inagami T, Eguchi S, Numaguchi K, Motley ED, Tang H, Matsumoto T, Yamakawa T. 1999. Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases. J Am Soc Nephrol 11:S57-S61.
19. Kinugawa K, Takahashi T, Kohmoto O, Yao A, Ikenouchi H, Serizawa T. 1995. Ca(2+)-growth coupling in angiotensin II-induced hypertrophy in cultured rat cardiac cells. Cardiovasc Res 30:419-431.
20. Lafon C, Mazars P, Guerrin M, Barboule N, Charcosset JY, Valette A. 1995. Early gene responses associated with transforming growth factor-beta 1 growth inhibition and autoinduction in MCF-7 breast adenocarcinoma cells. Biochem Biophys Acta 1266:288-295.
21. Levitzki A, Gazit A. 1995. Tyrosine kinase inhibition: An approach to drug development. Science 267:1782-1788.
22. Li X, Lee JW, Graves LM, Earp HS. 1998. Angiotensin II stimulates ERK via two pathways in epithelial cells: Protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway. EMBO J 17:2574-2583.
23. Liao DF, Monia B, Dean N, Berk BC. 1997. Protein kinase C-ζ mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells. J Biol Chem 272:6146-6150.
24. Liu WS, Heckman CA. 1998. The sevenfold way of PKC regulation. Cell Signal 10:529-542.
25. Luttrell LM, Daaka Y, Lefkowitz RJ. 1999. Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 11:177-183.
26. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
27. 2+/calmodulin-dependent transactivation of epidermal growth factor receptor. Circ Res 82:1338-1348.
28. + ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells. J Endocrinol 173:315-323.
29. Ransone LJ, Verma IM. 1990. Nuclear proto-oncogenes fos and jun. Annu Rev Cell Biol 6:539-557.
30. Sadoshima J, Izumo S. 1996. The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J 15:775-787.
31. Salomon DS, Brandt R, Ciardiello F, Normanno N. 1995. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19:183-232.
32. Selbie LA, Hill SJ. 1998. G protein-coupled-receptor cross-talk: The fine-tuning of multiple receptor-signalling pathways. Trends Pharmacol Sci 19:87-93.
33. Stoll M, Meffert S, Stroth U, Unger T. 1995. Growth or antigrowth: Angiotensin and the endothelium. J Hypertens 13:1529-1534.
34. Sutherland RL, Lee CS, Feldman RS, Musgrove EA. 1992. Regulation of breast cancer cell cycle progression by growth factors, steroids and steroid antagonists. J Steroid Biochem Mol Biol 41:315-321.
35. Tahmasebi M, Puddefoot JR, Inwang ER, Goode AW, Carpenter R, Vinson JP. 1998. Transcription of the prorenin gene in normal and diseared breast. Eur J Cancer 34:1777-1782.
36. Tian Y, Balla T, Baukal AJ, Catt KJ. 1995. Growth responses to angiotensin II in bovine adrenal glomerulosa cells. Am J Physiol 268:E135-E144.
37. Tian Y, Smith RD, Balla T, Catt KJ. 1998. Angiotensin II activates mitogen-activated protein kinase via protein kinase C and Ras/Raf-1 kinase in bovine adrenal glomerulosa cells. Endocrinology 139:1801-1809.
38. Timmermans PB, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JA, Smith RD. 1993. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 45:205-251.
39. Touyz RM, Schiffrin EL. 2000. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 52:639-672.
40. Veber N, Prevost G, Planchon P, Starzec A. 1994. Evidence for a growth effect of epidermal growth factor on MDA-MB-231 breast cancer cells. Eur J Cancer 30:1352-1359.
41. Xing C, Imagawa W. 1999. Altered MAP kinase (ERK1,2) regulation in primary cultures of mammary tumor cells: Elevated basal activity and sustained response to EGF. Carcinogenesis 20:1201-1208.
42. Yarden Y, Sliwkowski MX. 2001. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2:127-137.
43. Zhang J, Van Meel JC, Pfaffendorf M, Zhang J, Van Zwieten PA. 1994. Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta. Eur J Pharmacol 262:247-253.
44. Zhao Y, Neltner BS, Davis HW. 2000. Role of MARCKS in regulating endothelial cell proliferation. Am J Physiol 279:C1611-C1620.
45. Zou Y, Komuro I, Yamazaki T, Aikawa R, Kudoh S, Shiojima I, Hiroi Y, Mizuno T, Yazaki Y. 1996. Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes. J Biol Chem 27:33592-33597.
46. Zwich E, Hackel PO, Prenzel N, Ullrich A. 1999. The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20:408-412.