Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

EMBO Journal

Volumn 25, Issue 3, 2006, Pages 479-489

  Guthridge, Mark A ^a   Powell, Jason A ^a   Barry, Emma F ^a   Stomski, Frank C ^a   McClure, Barbara J ^a   Ramshaw, Hayley ^a   Felquer, Fernando A ^a   Dottore, Mara ^a   Thomas, Daniel T ^a   To, Bik ^a   Begley, C Glenn ^b   Lopez, Angel F ^a  

^a HANSON INSTITUTE   (Australia)

^b AMGEN INC   (United States)

Author keywords

14 3 3; Cell proliferation; Cell survival; Cytokine; Receptors

Indexed keywords

CELL SURFACE RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; GROWTH FACTOR; PROTEIN TYROSINE KINASE; RECEPTOR; SERINE; TYROSINE;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; DEREGULATION; FETUS; LEUKEMIA; MOUSE; NONHUMAN; PHOSPHORYLATION; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD11B; BINDING SITES; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; LEUKEMIA, MYELOID; MICE; MICE, KNOCKOUT; MUTATION; PHOSPHORYLATION; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; SERINE; SIGNAL TRANSDUCTION; TYROSINE;

ANIMALIA;

EID: 32544439898     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600948     Document Type: Article

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