A structural step into the SRP cycle

Molecular Microbiology

Volumn 53, Issue 2, 2004, Pages 357-363

  Wild, Klemens ^a   Rosendal, Ken R ^a,b   Sinning, Irmgard ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE; MEMBRANE RECEPTOR; RIBONUCLEOPROTEIN; SIGNAL PEPTIDE; SIGNAL RECOGNITION PARTICLE;

GENETIC CONSERVATION; MOLECULAR MODEL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; PROTEIN TARGETING; RECEPTOR AFFINITY; RNA BINDING; SHORT SURVEY; TRANSLATION INITIATION;

GUANOSINE TRIPHOSPHATE; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, PEPTIDE; RIBOSOMES; SIGNAL RECOGNITION PARTICLE;

MAMMALIA;

EID: 3242876011     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04139.x     Document Type: Short Survey

References (55)

1. Bacher, G., Lutcke, H., Jungnickel, B., Rapoport, T.A., and Dobberstein, B. (1996) Regulation by the ribosome of the GTPase of the signal-recognition particle during protein targeting. Nature 381: 248-251.
2. Batey, R.T., Rambo, R.P., Lucast, L., Rha, B., and Doudna, J.A. (2000) Crystal structure of the ribonucleoprotein core of the signal recognition particle. Science 287: 1232-1239.
3. Beckmann, R., Bubeck, D., Grassucci, R., Penczek, P., Verschoor, A., Blobel, G., and Frank, J. (1997) Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science 278: 2123-2126.
4. Bernstein, H.D., Poritz, M.A., Strub, K., Hoben, P.J., Brenner, S., and Walter, P. (1989) Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature 340: 482-486.
5. Birse, D.E., Kapp, U., Strub, K., Cusack, S., and Aberg, A. (1997) The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14. EMBO J 16: 3757-3766.
6. Bourne, H.R., Sanders, D.A., and McCormick, F. (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349: 117-127.
7. Carson, M. (1997) Ribbons. Methods Enzymol 277: 493-505.
8. Connolly, T., Rapiejko, P.J., and Gilmore, R. (1991) Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor. Science 252: 1171-1173.
9. Dalbey, R.E., and Kuhn, A. (2000) Evolutionary related insertion pathways of bacterial, mitochondrial, and thylakoid membrane proteins. Annu Rev Cell Dev Biol 16: 51-87.
10. Diener, J.L., and Wilson, C. (2000) Role of SRP19 in assembly of the Archaeoglobus fulgidus signal recognition particle. Biochemistry 39: 12862-12874.
11. Egea, P.F., Shan, S.O., Napetschnig, J., Savage, D.F., Walter, P., and Stroud, R.M. (2004) Substrate twinning activates the signal recognition particle and its receptor. Nature 427: 215-221.
12. Esnouf, R.M. (1997) An extensively modified version of Mol-Script that includes greatly enhanced coloring capabilities. J Mol Graph 15: 133-138.
13. Focia, P.J., Shepotinovskaya, I.V., Seidler, J.A., and Freymann, D.M. (2004) Heterodimeric GTPase core of the SRP targeting complex. Science 303: 373-377.
14. Freymann, D.M., Keenan, R.J., Stroud, R.M., and Walter, P. (1997) Structure of the conserved GTPase domain of the signal recognition particle. Nature 385: 361-364.
15. Fulga, T.A., Sinning, I., Dobberstein, B., and Pool, M.R. (2001) SRbeta coordinates signal sequence release from SRP with ribosome binding to the translocon. EMBO J 20: 2338-2347.
16. Gundelfinger, E.D., Krause, E., Melli, M., and Dobberstein, B. (1983) The organization of the 7SL RNA in the signal recognition particle. Nucleic Acids Res 11: 7363-7374.
17. Hainzl, T., Huang, S., and Sauer-Eriksson, A.E. (2002) Structure of the SRP19 RNA complex and implications for signal recognition particle assembly. Nature 417: 767-771.
18. Halic, M., Becker, T., Pool, M.R., Spahn, C.M., Grassucci, R.A., Frank, J., and Beckmann, R. (2004) Structure of the signal recognition particle interacting with the elongation-arrested ribosome. Nature 427: 808-814.
19. Keenan, R.J., Freymann, D.M., Walter, P., and Stroud, R.M. (1998) Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell 94: 181-191.
20. Keenan, R.J., Freymann, D.M., Stroud, R.M., and Walter, P. (2001) The signal recognition particle. Annu Rev Biochem 70: 755-775.
21. Krieg, U.C., Walter, P., and Johnson, A.E. (1986) Photo-crosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci USA 83: 8604-8608.
22. Kuglstatter, A., Oubridge, C., and Nagai, K. (2002) Induced structural changes of 7SL RNA during the assembly of human signal recognition particle. Nature Struct Biol 9: 740-744.
23. Kurzchalia, T.V., Wiedmann, M., Girshovich, A.S., Bochkareva, E.S., Bielka, H., and Rapoport, T.A. (1986) The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle. Nature 320: 634-636.
24. Lu, Y., Qi, H.Y., Hyndman, J.B., Ulbrandt, N.D., Teplyakov, A., Tomasevic, N., and Bernstein, H.D. (2001) Evidence for a novel GTPase priming step in the SRP protein targeting pathway. EMBO J 20: 6724-6734.
25. Luirink, J., ten Hagen-Jongman, C.M., van der Weijden, C.C., Oudega, B., High, S., Dobberstein, B., and Kusters, R. (1994) An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY. EMBO J 13: 2289-2296.
26. Lutcke, H. (1995) Signal recognition particle (SRP), a ubiquitous initiator of protein translocation. Eur J Biochem 228: 531-550.
27. Lutcke, H., High, S., Romisch, K., Ashford, A.J., and Dobberstein, B. (1992) The methionine-rich domain of the 54 kDa subunit of signal recognition particle is sufficient for the interaction with signal sequences. EMBO J 11: 1543-1551.
28. Merritt, E.A., and Bacon, D.J. (1997) Raster3D: photorealistic molecular graphics. Macromol Crystallogr 277: 505-524.
29. Montoya, G., Svensson, C., Luirink, J., and Sinning, I. (1997) Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature 385: 365-368.
30. Montoya, G., te Kaat, K., Moll, R., Schafer, G., and Sinning, I. (2000) The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex. Struct Fold Des 8: 515-525.
31. Nagai, K., Oubridge, C., Kuglstatter, A., Menichelli, E., Isel, C., and Jovine, L. (2003) New EMBO member's review: structure, function and evolution of the signal recognition particle. EMBO J 22: 3479-3485.
32. Newitt, J.A., and Bernstein, H.D. (1997) The N-domain of the signal recognition particle 54-kDa subunit promotes efficient signal sequence binding. Eur J Biochem 245: 720-729.
33. Ogg, S.C., and Walter, P. (1995) SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. Cell 81: 1075-1084.
34. Oubridge, C., Kuglstatter, A., Jovine, L., and Nagai, K. (2002) Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle. Mol Cell 9: 1251-1261.
35. Politz, J.C., Yarovoi, S., Kilroy, S.M., Gowda, K., Zwieb, C., and Pederson, T. (2000) Signal recognition particle components in the nucleolus. Proc Natl Acad Sci USA 97: 55-60.
36. Pool, M.R., Stumm, J., Fulga, T.A., Sinning, I., and Dobberstein, B. (2002) Distinct modes of signal recognition particle interaction with the ribosome. Science 297: 1345-1348.
37. Powers, T., and Walter, P. (1995) Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases. Science 269: 1422-1424.
38. Ramirez, U.D., Minasov, G., Focia, P.J., Stroud, R.M., Walter, P., Kuhn, P., and Freymann, D.M. (2002) Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh. J Mol Biol 320: 783-799.
39. Romisch, K., Webb, J., Herz, J., Prehn, S., Frank, R., Vingron, M., and Dobberstein, B. (1989) Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains. Nature 340: 478-482.
40. Romisch, K., Webb, J., Lingelbach, K., Gausepohl, H., and Dobberstein, B. (1990) The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain. J Cell Biol 111: 1793-1802.
41. Rosenblad, M.A., Gorodkin, J., Knudsen, B., Zwieb, C., and Samuelsson, T. (2003) SRPDB: Signal Recognition Particle Database. Nucleic Acids Res 31: 363-364.
42. Rosendal, K.R., Wild, K., Montoya, G., and Sinning, I. (2003) Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication. Proc Natl Acad Sci USA 100: 14701-14706.
43. Sauer-Eriksson, A.E., and Hainzl, T. (2003) S-domain assembly of the signal recognition particle. Curr Opin Struct Biol 13: 64-70.
44. Schwartz, T., and Blobel, G. (2003) Structural basis for the function of the Beta subunit of the eukaryotic signal recognition particle receptor. Cell 112: 793-803.
45. Sprang, S.R. (1997) G protein mechanisms: insights from structural analysis. Annu Rev Biochem 66: 639-678.
46. Tajima, S., Lauffer, L., Rath, V.L., and Walter, P. (1986) The signal recognition particle receptor is a complex that contains two distinct polypeptide chains. J Cell Biol 103: 1167-1178.
47. Terzi, L., Pool, M.R., Dobberstein, B., and Strub, K. (2004) Signal recognition particle Alu domain occupies a defined site at the ribosomal subunit interface upon signal sequence recognition. Biochemistry 43: 107-117.
48. Van den Berg, B., Clemons, W.M., Jr, Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., and Rapoport, T.A. (2004) X-ray structure of a protein-conducting channel. Nature 427: 36-44.
49. Walter, P., Ibrahimi, I., and Blobel, G. (1981) Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in vitro-assembled polysomes synthesizing secretory protein. J Cell Biol 91: 545-550.
50. Weichenrieder, O., Wild, K., Strub, K., and Cusack, S. (2000) Structure and assembly of the Alu domain of the mammalian signal recognition particle. Nature 408: 167-173.
51. Weichenrieder, O., Stehlin, C., Kapp, U., Birse, D.E., Timmins, P.A., Strub, K., and Cusack, S. (2001) Hierarchical assembly of the Alu domain of the mammalian signal recognition particle. RNA 7: 731-740.
52. Weiner, A.M., Deininger, P.L., and Efstratiadis, A. (1986) Nonviral retroposons: genes, pseudogenes, and transposable elements generated by the reverse flow of genetic information. Annu Rev Biochem 55: 631-661.
53. Wild, K., Sinning, I., and Cusack, S. (2001) Crystal structure of an early protein-RNA assembly complex of the signal recognition particle. Science 294: 598-601.
54. Zopf, D., Bernstein, H.D., Johnson, A.E., and Walter, P. (1990) The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J 9: 4511-4517.
55. Zwieb, C., and Eichler, J. (2002) Getting on target: the archaeal signal recognition particle. Archaea 1: 27-34.