Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 7, 2003, Pages 4090-4095

  Hofbauer, Monika ^a,b   Wiesener, Solveigh ^a,b   Babbe, Holger ^c   Roers, Axel ^c   Wekerle, Hartmut ^b   Dornmair, Klaus ^a,b   Hohlfeld, Reinhard ^a,b   Goebels, Norbert ^a,b,d  

^a UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PRIMER DNA;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; AUTOIMMUNE DISEASE; BLOOD CELL; CELL CLONE; CHROMOSOME MICRODISSECTION; CLINICAL ARTICLE; CLONOGENESIS; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; FEMALE; FROZEN SECTION; GENE AMPLIFICATION; GENE REARRANGEMENT; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; LASER; MALE; MUSCLE BIOPSY; MUSCLE TISSUE; NORMAL DISTRIBUTION; NUCLEOTIDE TRANSPORT; PATHOGENESIS; POLYMERASE CHAIN REACTION; POLYMYOSITIS; PRIORITY JOURNAL; PROTEIN MOTIF; SINGLE CELL POLYMERASE CHAIN REACTION; SPECTROSCOPY; STAINING; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE RECEPTOR GENE; ADULT; AGED; BIOPSY; BLOOD; CHEMISTRY; DISSECTION; GENETICS; IMMUNOLOGY; METHODOLOGY; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; SKELETAL MUSCLE; T LYMPHOCYTE;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ANTIGENS, CD; BASE SEQUENCE; BIOPSY; DISSECTION; DNA PRIMERS; FEMALE; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; POLYMERASE CHAIN REACTION; POLYMYOSITIS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 0037388305     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0236183100     Document Type: Article

References (43)

1. Pannetier, C., Even, J. & Kourilsky, P. (1995) Immunol. Today 16, 176-181.
2. Hingorani, R., Choi, I.-H., Akolkar, P., Gulwani-Akolkar, B., Pergolizzi, R., Silver, J. & Gregersen, P. K. (1993) J. Immunol. 151, 5762-5769.
3. Posnett, D. N., Sinha, R., Kabak, S. & Russo, C. (1994) J. Exp. Med. 179, 609-618.
4. Schwab, R., Szabo, P., Manavalan, J. S., Weksler, M. E., Posnett, D. N., Pannetier, C., Kourilsky, P. & Even, J. (1997) J. Immunol. 158, 4493-4499.
5. Chamberlain, W. D., Falta, M. T. & Kotzin, B. L. (2000) Clin. Immunol. 94, 160-172.
6. Scotet, E., Peyrat, M.-A., Saulquin, X., Retière, C., Couedel, C., Davodeau, F., Dulphy, N., Toubert, A., Bignon, J. D., Lim, A., et al. (1999) Eur. J. Immunol. 29, 973-985.
7. Masopust, D., Vezys, V., Marzo, A. L. & Lefrancois, L. (2001) Science 291, 2413-2417.
8. Dalakas, M. C. (1991) N. Engl. J. Med. 325, 1487-1498.
9. Karpati, G. & Carpenter, S. (1993) in Baillière's Clinical Neurology, ed. Mastaglia, F. L. (Baillière Tindall, London), pp. 527-556.
10. Engel, A. G., Hohlfeld, R. & Banker, B. Q. (1994) in Myology, eds. Engel, A. G. & Franzini-Armstrong, C. (McGraw-Hill, New York), pp. 1335-1383.
11. Plotz, P. H. (1999) Ann. Intern. Med. 122, 715-724.
12. O'Hanlon, T. P. & Miller, F. W. (1995) Curr. Opin. Rheumatol. 7, 503-509.
13. Goebels, N., Michaelis, D., Engelhardt, M., Huber, S., Bender, A., Pongratz, D., Johnson, M. A., Wekerle, H., Tschopp, J., Jenne, D., et al. (1996) J. Clin. Invest. 97, 2905-2910.
14. Arahata, K. & Engel, A. G. (1986) Ann. Neurol. 19, 112-125.
15. Fox, S. A., Finklestone, E., Robbins, P. D., Mastaglia, F. L. & Swanson, N. R. (1994) J. Neurol. Sci. 125, 70-76.
16. Jongen, P. J. H., Zoll, G. J., Beaumont, M., Melchers, W. J. G., Van de Putte, L. B. A. & Galama, J. M. D. (1993) Ann. Rheum. Dis. 52, 575-578.
17. Leon-Monzon, M. & Dalakas, M. C. (1992) Ann. Neurol. 32, 219-222.
18. Leff, R. L., Love, L. A., Miller, F. W., Greenberg, S. J., Klein, E. A., Dalakas, M. C. & Plotz, P. H. (1992) Lancet 339, 1192-1195.
19. Babbe, H., Roers, A., Waisman, A., Lassmann, H., Goebels, N., Hohlfeld, R., Friese, M., Schröder, R., Deckert, M., Schmidt, S., et al. (2000) J. Exp. Med. 192, 393-404.
20. Monteiro, J., Hingorani, R., Peroglizzi, R., Apatoff, B. & Gregersen, P. K. (1996) Autoimmunity 23, 127-138.
21. Puisieux, I., Even, J., Pannetier, C., Jotereau, F., Favrot, M. & Kourilsky, P. (1994) J. Immunol. 153, 2807-2818.
22. Emmert-Buck, M. R., Bonner, R. F., Smith, P. D., Chuaqui, R. F., Zhuang, Z., Goldstein, S. R., Weiss, R. A. & Liotta, L. A. (1996) Science 274, 998-1001.
23. Roers, A., Montesinos-Rongen, M., Hansmann, M. L., Rajewsky, K. & Kuppers, R. (1998) Eur. J. Immunol. 28, 2424-2431.
24. Bender, A., Ernst, N., Iglesias, A., Dornmair, K., Wekerle, H. & Hohlfeld, R. (1995) J. Exp. Med. 181, 1863-1868.
25. Arahata, K. & Engel, A. G. (1984) Ann. Neurol. 16, 193-208.
26. Liblau, R. S., Wong, F. S., Mars, L. T. & Santamaria, P. (2002) Immunity 17, 1-6.
27. Steinman, L. (2001) J. Exp. Med. 194, F27-F30.
28. Engel, A. G. & Arahata, K. (1984) Ann. Neurol. 16, 209-216.
29. Emslie-Smith, A. M., Arahata, K. & Engel, A. G. (1989) Hum. Pathol. 20, 224-231.
30. Karpati, G., Pouliot, Y. & Carpenter, S. (1988) Ann. Neurol. 23, 64-72.
31. Orimo, S., Koga, R., Nakamura, K., Arai, M., Tamaki, M., Sugita, H., Nanaka, I. & Arahata, K. (1994) Neuromusc. Disord. 4, 219-226.
32. Cherin, P., Herson, S., Crevon, M. C., Hauw, J.-J., Cervera, P., Galanaud, P. & Emilie, D. (1996) J. Rheumatol. 23, 1135-1142.
33. Hohlfeld, R. & Engel, A. G. (1991) Ann. Neurol. 29, 498-507.
34. Lindberg, C., Oldfors, A. & Tarkowski, A. (1994) Eur. J. Immunol. 24, 2659-2663.
35. O'Hanlon, T. P., Dalakas, M. C., Plotz, P. H. & Miller, F. W. (1994) J. Immunol. 152, 2569-2576.
36. Mantegazza, R., Andreetta, F., Bernasconi, P., Baggi, F., Oksenberg, J. R., Simoncini, O., Mora, M., Cornelio, F. & Steinman, L. (1993) J. Clin. Invest. 91, 2880-2886.
37. Nishio, J., Suzuki, M., Miyasaka, N. & Kohsaka, H. (2001) J. Immunol. 167, 4051-4058.
38. Benveniste, O., Cherin, P., Maisonobe, T., Merat, R., Chosidow, O., Mouthon, L., Guillevin, L., Flahault, A., Burland, M. C., Klatzmann, D., et al. (2001) J. Immunol. 167, 3521-3529.
39. Fend, F., Emmert-Buck, M. R., Chuaqui, R., Cole, K., Lee, J., Liotta, L. A. & Raffeld, M. (2000) Am. J. Pathol. 154, 61-66.
40. Amemiya, K., Granger, R. P. & Dalakas, M. C. (2000) Brain 123, 2030-2039.
41. Flavell, R. A. & Hafler, D. A. (1999) Curr. Opin. Immunol. 11, 635-637.
42. Marrack, P., Kappler, J. & Kotzin, B. L. (2001) Nat. Med. 7, 899-905.
43. Martin, R., Sturzebecher, C. S. & McFarland, H. F. (2001) Nat. Immunol. 2, 785-788.