Efficient gene transfer of a simian immunodeficiency viral vector into cardiomyocytes derived from primate embryonic stem cells

Journal of Gene Medicine

Volumn 5, Issue 11, 2003, Pages 921-928

  Nagata, Mihoko ^a   Takahashi, Masafumi ^a   Muramatsu, Shin Ichi ^a   Ueda, Yasuji ^b   Hanazono, Yutaka ^a   Takeuchi, Koichi ^a   Okada, Koji ^a   Suzuki, Yutaka ^c   Kondo, Yasushi ^c   Suemori, Masafumi ^d   Ikeda, Uichi ^a   Nakano, Imaharu ^a   Kobayashi, Eiji ^a   Hasegawa, Mamoru ^b   Ozawa, Keiya ^a   Nakatsuji, Norio ^d   Shimada, Kazuyuki ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b DNAVEC Research Inc   (Japan)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Cardiomyocyte; Cell transplantation; Embryonic stem cell; Myocardial infarction; Simian immunodeficiency virus

Indexed keywords

CALCIUM ION; ENHANCED GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; VIRUS VECTOR; CALCIUM; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; EMBRYO; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HEART INFARCTION; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; MALE; MONKEY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIMIAN IMMUNODEFICIENCY VIRUS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STEM CELL; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; COMPARATIVE STUDY; CYTOLOGY; ELECTRON MICROSCOPY; GENE VECTOR; GENETICS; HEART MUSCLE; MACACA; METABOLISM; PLURIPOTENT STEM CELL; SPECTROFLUOROMETRY; TRANSPORT AT THE CELLULAR LEVEL; ULTRASTRUCTURE;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; DNA PRIMERS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; LUMINESCENT PROTEINS; MACACA FASCICULARIS; MICROSCOPY, ELECTRON; MYOCARDIUM; PLURIPOTENT STEM CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIMIAN IMMUNODEFICIENCY VIRUS; SPECTROMETRY, FLUORESCENCE;

EID: 3242714342     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.431     Document Type: Article

References (33)

1. Anversa P, Fitzpatrick D, Argani S, et al. Myocyte mitotic division in the aging mammalian rat heart. Circ Res 1991; 69: 1159-1164.
2. Kehat I, Kenyagin-Karsenti D, Snir M, et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001; 108 407-414.
3. Xu C, Police S, Rao N, et al. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res 2002; 91: 501-508.
4. Boheler KR, Czyz J, Tweedie D, et al. Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res 2002; 91: 189-201.
5. Kehat I, Gepstein A, Spira A, et al. High-resolution electrophysiological assessment of human embryonic stem cell-derived cardiomyocytes: a novel in vitro model for the study of conduction. Circ Res 2002; 91: 659-661.
6. Suemori H, Tada T, Torii R, et al. Establishment of embryonic stem cell lines from cynomolgus monkey blastocysts produced by IVF or ICSI. Dev Dyn 2001; 222: 273-279.
7. Cherry SR, Biniszkiewicz D, van Parijs L, et al. Retroviral expression in embryonic stem cells and hematopoietic stem cells. Mol Cell Biol 2000; 20: 7419-7426.
8. Grez M, Akgun E, Hilberg F, et al. Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells. Proc Natl Acad Sci U S A 1990; 87: 9202-9206.
9. Loh TP, Sievert LL, Scott RW. Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells. Mol Cell Biol 1990; 10: 4045-4057.
10. Eiges R, Schuldiner M, Drukker M, et al. Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells. Curr Biol 2001; 11: 514-518.
11. Blomer U, Naldini L, Kafri T, et al. Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J Virol 1997; 71: 6641-6649.
12. Kafri T, Blomer U, Peterson DA, et al. Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet 1997; 17: 314-317.
13. Miyoshi H, Takahashi M, Gage FH, et al. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A 1997; 94: 10 319-10 323.
14. Asano T, Hanazono Y, Ueda Y, et al. Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector. Mol Ther 2002; 6: 162-168.
15. Kamitani T, Ikeda U, Muto S, et al. Regulation of Na, K-ATPase gene expression by thyroid hormone in rat cardiocytes. Circ Res 1992; 71: 1457-1464.
16. Okada K, Ishikawa S, Saito T. Enhancement of intracellular sodium by vasopressin in spontaneously hypertensive rats. Hypertension 1993; 22: 300-305.
17. Nakajima T, Nakamaru K, Ido E, et al. Development of novel simian immunodeficiency virus vectors carrying a dual gene expression system. Hum Gene Ther 2000; 11: 1863-1874.
18. Scorsin M, Marotte F, Sabri A, et al. Can grafted cardiomyocytes colonize peri-infarct myocardial areas? Circulation 1996; 94: II337-340.
19. Li RK, Jia ZQ, Weisel RD, et al. Cardiomyocyte transplantation improves heart function. Ann Thorac Surg 1996; 62: 654-660; discussion 660-661.
20. Reinecke H, Zhang M, Bartosek T, et al. Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation 1999; 100: 193-202.
21. Yoon PD, Kao RL, Magovern GJ. Myocardial regeneration. Transplanting satellite cells into damaged myocardium. Tex Heart Inst J 1995; 22: 119-125.
22. Chiu RC, Zibaitis A, Kao RL. Cellular cardiomyoplasty: myocardial regeneration with satellite cell implantation. Ann Thorac Surg 1995; 60: 12-18.
23. Menasche P, Hagege A, Scorsin M, et al. Autologous skeletal myoblast transplantation for cardiac insufficiency. First clinical case. Arch Mal Coeur Vaiss 2001; 94: 180-182.
24. Tomita S, Li RK, Weisel RD, et al. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 1999; 100: II247-256.
25. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
26. Zhang M, Methot D, Poppa V, et al. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 2001; 33: 907-921.
27. Metzger JM, Lin WI, Johnston RA, et al. Myosin heavy chain expression in contracting myocytes isolated during embryonic stem cell cardiogenesis. Circ Res 1995; 76: 710-719.
28. Maltsev VA, Wobus AM, Rohwedel J, et al. Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents. Circ Res 1994; 75: 233-244.
29. Hescheler J, Fleischmann BK, Lentini S, et al. Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis. Cardiovasc Res 1997; 36: 149-162.
30. Klug MG, Soonpaa MH, Koh GY, et al. Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest 1996; 98: 216-224.
31. Losordo DW, Vale PR, Hendel RC, et al. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation 2002; 105: 2012-2018.
32. Udelson JE, Dilsizian V, Laham RJ, et al. Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery disease. Circulation 2000; 102: 1605-1610.
33. Pfeifer A, Brandon EP, Kootstra N, et al. Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A 2001; 98: 11 450-11 455.