-
1
-
-
0025283892
-
Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
-
Panza JA, Quyyumi AA, Brush JE, Epstein SE 1990 Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 223:22-27
-
(1990)
N Engl J Med
, vol.223
, pp. 22-27
-
-
Panza, J.A.1
Quyyumi, A.A.2
Brush, J.E.3
Epstein, S.E.4
-
2
-
-
0030884022
-
Endothelial dysfunction: Cause of the insulin resistance syndrome
-
Pinkney JH, Stehouwer CD, Coppack SW, Yudkin JS 1997 Endothelial dysfunction: cause of the insulin resistance syndrome. Diabetes 46(Suppl 2):S9-S13
-
(1997)
Diabetes
, vol.46
, Issue.2 SUPPL.
-
-
Pinkney, J.H.1
Stehouwer, C.D.2
Coppack, S.W.3
Yudkin, J.S.4
-
3
-
-
0035838416
-
Prognostic significance of endothelium dysfunction in hypertensive patients
-
Perticone F, Ceravolo R, Pujia A, Ventura G, Iacopino S, Scozzafava A, Ferraro A, Chello M, Mastroroberto P, Verdecchia P, Schillaci G 2001 Prognostic significance of endothelium dysfunction in hypertensive patients. Circulation 104:191-196
-
(2001)
Circulation
, vol.104
, pp. 191-196
-
-
Perticone, F.1
Ceravolo, R.2
Pujia, A.3
Ventura, G.4
Iacopino, S.5
Scozzafava, A.6
Ferraro, A.7
Chello, M.8
Mastroroberto, P.9
Verdecchia, P.10
Schillaci, G.11
-
4
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ 2000 Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101:1539-1545
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
Cong, L.N.4
Kirby, M.5
Mostowski, H.6
Quon, M.J.7
-
5
-
-
0034651949
-
Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin
-
Kuboki K, Jiang ZY, Takahara N, Ha SW, Igarashi M, Yamauchi T, Feener EP, Herbert TP, Rhodes CJ, King GL 2000 Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation 101:676-681
-
(2000)
Circulation
, vol.101
, pp. 676-681
-
-
Kuboki, K.1
Jiang, Z.Y.2
Takahara, N.3
Ha, S.W.4
Igarashi, M.5
Yamauchi, T.6
Feener, E.P.7
Herbert, T.P.8
Rhodes, C.J.9
King, G.L.10
-
6
-
-
0038665339
-
The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance
-
Vicent D, Ilany J, Kondo T, Naruse K, Fisher SJ, Kisanuki YY, Bursell S, Yanagisawa M, King GL, Kahn CR 2003 The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest 111:1373-1380
-
(2003)
J Clin Invest
, vol.111
, pp. 1373-1380
-
-
Vicent, D.1
Ilany, J.2
Kondo, T.3
Naruse, K.4
Fisher, S.J.5
Kisanuki, Y.Y.6
Bursell, S.7
Yanagisawa, M.8
King, G.L.9
Kahn, C.R.10
-
7
-
-
0032523085
-
Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin-receptor substrate-1
-
Abe H, Yamada N, Kamata K, Kuwaki T, Shimada M, Osuga J, Shionoiri F, Yahagi N, Kadowaki T, Tamemoto H, Ishibashi S, Yazaki Y, Makuuchi M 1998 Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin-receptor substrate-1. J Clin Invest 101:1784-1788
-
(1998)
J Clin Invest
, vol.101
, pp. 1784-1788
-
-
Abe, H.1
Yamada, N.2
Kamata, K.3
Kuwaki, T.4
Shimada, M.5
Osuga, J.6
Shionoiri, F.7
Yahagi, N.8
Kadowaki, T.9
Tamemoto, H.10
Ishibashi, S.11
Yazaki, Y.12
Makuuchi, M.13
-
8
-
-
0034810894
-
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
-
Sesti G, Federici M, Hribal ML, Lauro D, Sbraccia P, Lauro R 2001 Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. FASEB J 15:2099-2111
-
(2001)
FASEB J
, vol.15
, pp. 2099-2111
-
-
Sesti, G.1
Federici, M.2
Hribal, M.L.3
Lauro, D.4
Sbraccia, P.5
Lauro, R.6
-
9
-
-
0027367546
-
Amino acid polymorphism of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus
-
Almind K, Bjorbaek C, Vestergaard H, Hansen T, Echwald S, Pedersen O 1993 Amino acid polymorphism of insulin receptor substrate-1 in non-insulin- dependent diabetes mellitus. Lancet 342:828-832
-
(1993)
Lancet
, vol.342
, pp. 828-832
-
-
Almind, K.1
Bjorbaek, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.5
Pedersen, O.6
-
10
-
-
0028557255
-
Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus
-
Imai Y, Fusco A, Suzuki Y, Lesniak MA, D'Alfonso R, Sesti G, Bertoli A, Lauro R, Accili D, Taylor SI 1994 Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 79:1655-1658
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 1655-1658
-
-
Imai, Y.1
Fusco, A.2
Suzuki, Y.3
Lesniak, M.A.4
D'Alfonso, R.5
Sesti, G.6
Bertoli, A.7
Lauro, R.8
Accili, D.9
Taylor, S.I.10
-
11
-
-
0028912848
-
Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease
-
Hitman GA, Hawrami K, McCarthy MI, Viswanathan M, Snehalatha C, Ramachandran A, Tuomilehto J, Tuomilehto-Wolf E, Nissinen A, Pedersen O 1995 Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease. Diabetologia 38:481-486
-
(1995)
Diabetologia
, vol.38
, pp. 481-486
-
-
Hitman, G.A.1
Hawrami, K.2
McCarthy, M.I.3
Viswanathan, M.4
Snehalatha, C.5
Ramachandran, A.6
Tuomilehto, J.7
Tuomilehto-Wolf, E.8
Nissinen, A.9
Pedersen, O.10
-
12
-
-
0029857775
-
UKPDS 19: Heterogeneity in NIDDM: Separate contributions of IRS-1 and β3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations
-
Zhang Y, Wat N, Stratton IM, Warren-Perry MG, Orho M, Groop L, Turner RC 1996 UKPDS 19: heterogeneity in NIDDM: separate contributions of IRS-1 and β3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations. Diabetologia 39:1505-1511
-
(1996)
Diabetologia
, vol.39
, pp. 1505-1511
-
-
Zhang, Y.1
Wat, N.2
Stratton, I.M.3
Warren-Perry, M.G.4
Orho, M.5
Groop, L.6
Turner, R.C.7
-
13
-
-
0030000562
-
Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus
-
Sigal RJ, Doria A, Warram JH, Krolewski AS 1996 Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 81:1657-1659
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1657-1659
-
-
Sigal, R.J.1
Doria, A.2
Warram, J.H.3
Krolewski, A.S.4
-
14
-
-
0027994029
-
Insulin receptor substrate-1 variants in non-insulin-dependent diabetes
-
Laakso M, Malkki M, Kekalainen P, Kuusisto J, Deeb SS 1994 Insulin receptor substrate-1 variants in non-insulin-dependent diabetes. J Clin Invest 94:1141-1146
-
(1994)
J Clin Invest
, vol.94
, pp. 1141-1146
-
-
Laakso, M.1
Malkki, M.2
Kekalainen, P.3
Kuusisto, J.4
Deeb, S.S.5
-
15
-
-
0029071130
-
Insulin receptor substrate-1 gene and cardiovascular risk factors in NIDDM
-
Grant PJ, Stickland MH, Mansfield MW 1995 Insulin receptor substrate-1 gene and cardiovascular risk factors in NIDDM. Lancet 346:841-842
-
(1995)
Lancet
, vol.346
, pp. 841-842
-
-
Grant, P.J.1
Stickland, M.H.2
Mansfield, M.W.3
-
16
-
-
0029893417
-
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling
-
Almind K, Inoue G, Pedersen O, Kahn CR 1996 A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. J Clin Invest 97:2569-2575
-
(1996)
J Clin Invest
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pedersen, O.3
Kahn, C.R.4
-
17
-
-
0034351407
-
972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells
-
972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. J Clin Endocrinol Metab 85:2004-2013
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2004-2013
-
-
Hribal, M.L.1
Federici, M.2
Porzio, O.3
Lauro, D.4
Borboni, P.5
Accili, D.6
Lauro, R.7
Sesti, G.8
-
18
-
-
0035220244
-
972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets
-
972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets. FASEB J 15:22-24
-
(2001)
FASEB J
, vol.15
, pp. 22-24
-
-
Federici, M.1
Hribal, M.L.2
Ranalli, M.3
Marselli, L.4
Porzio, O.5
Lauro, D.6
Borboni, P.7
Lauro, R.8
Marchetti, P.9
Melino, G.10
Sesti, G.11
-
19
-
-
9144222572
-
G972R IRS-1 variant impairs insulin regulation of eNOS in cultured human endothelial cells
-
Federici M, Pandolfi A, De Filippis EA, Pellegrini G, Menghini R, Lauro D, Cardellini M, Romano M, Sesti G, Lauro R, Consoli A 2004 G972R IRS-1 variant impairs insulin regulation of eNOS in cultured human endothelial cells. Circulation 109:300-405
-
(2004)
Circulation
, vol.109
, pp. 300-405
-
-
Federici, M.1
Pandolfi, A.2
De Filippis, E.A.3
Pellegrini, G.4
Menghini, R.5
Lauro, D.6
Cardellini, M.7
Romano, M.8
Sesti, G.9
Lauro, R.10
Consoli, A.11
-
20
-
-
0021813187
-
Homeostatic model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner R 1985 Homeostatic model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.6
-
21
-
-
0037762778
-
972→Arg IRS-1 variant is associated with type 1 diabetes in Continental Italy
-
972→Arg IRS-1 variant is associated with type 1 diabetes in Continental Italy. Diabetes 52:887-890
-
(2003)
Diabetes
, vol.52
, pp. 887-890
-
-
Federici, M.1
Petrone, A.2
Porzio, O.3
Bizzarri, C.4
Lauro, D.5
D'Alfonso, R.6
Patera, I.7
Cappa, M.8
Nistico, L.9
Baroni, M.10
Sesti, G.11
Di Mario, U.12
Lauro, R.13
Buzzetti, R.14
-
22
-
-
18844474651
-
A common mutation of the insulin receptor substrate-1 gene is a risk factor for coronary artery disease
-
Baroni MG, D'Andrea MP, Montali A, Pannitteri G, Barilla F, Campagna F, Mazzei E, Lovari S, Seccareccia F, Campa PP, Ricci G, Pozzilli P, Urbinati G, Arca M 1999 A common mutation of the insulin receptor substrate-1 gene is a risk factor for coronary artery disease. Arterioscler Thromb Vasc Biol 19:2975-2980
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2975-2980
-
-
Baroni, M.G.1
D'Andrea, M.P.2
Montali, A.3
Pannitteri, G.4
Barilla, F.5
Campagna, F.6
Mazzei, E.7
Lovari, S.8
Seccareccia, F.9
Campa, P.P.10
Ricci, G.11
Pozzilli, P.12
Urbinati, G.13
Arca, M.14
-
23
-
-
0029118510
-
Insulin resistance: Interaction between obesity and a common variant of insulin receptor substrate-1
-
Clausen JO, Hansen T, Bjorbaek C, Echwald SM, Urhammer SA, Rasmussen S, Andersen CB, Hansen L, Almind K, Winther K 1995 Insulin resistance: interaction between obesity and a common variant of insulin receptor substrate-1. Lancet 346:397-402
-
(1995)
Lancet
, vol.346
, pp. 397-402
-
-
Clausen, J.O.1
Hansen, T.2
Bjorbaek, C.3
Echwald, S.M.4
Urhammer, S.A.5
Rasmussen, S.6
Andersen, C.B.7
Hansen, L.8
Almind, K.9
Winther, K.10
-
24
-
-
0036094165
-
Genome-wide linkage analysis of the acute coronary syndrome suggests a locus on chromosome 2
-
Harrap SB, Zammit KS, Wong ZY, Williams FM, Bahlo M, Tonkin AM, Anderson ST 2002 Genome-wide linkage analysis of the acute coronary syndrome suggests a locus on chromosome 2. Arterioscler Thromb Vasc Biol 22:874-878
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 874-878
-
-
Harrap, S.B.1
Zammit, K.S.2
Wong, Z.Y.3
Williams, F.M.4
Bahlo, M.5
Tonkin, A.M.6
Anderson, S.T.7
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