Id3-mediated enhancement of cisplatin-induced apoptosis in a sarcoma cell line MG-63

Anticancer Research

Volumn 24, Issue 3 A, 2004, Pages 1519-1524

  Koyama, Takashi ^a   Suzuki, Hidekazu ^a   Imakiire, Atsuhiro ^a   Yanase, Noriko ^a   Hata, Kikumi ^a   Mizuguchi, Junichiro ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; CDDP; Id; Sarcoma

Indexed keywords

CASPASE 3; CISPLATIN; HELIX LOOP HELIX PROTEIN; HYDROETHIDINE; INHIBITOR OF DIFFERENTIATION 2; INHIBITOR OF DIFFERENTIATION 3; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMA CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BONE NEOPLASMS; CASPASE 3; CASPASES; CELL DIVISION; CELL LINE, TUMOR; CISPLATIN; ENZYME ACTIVATION; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; NEOPLASM PROTEINS; OSTEOSARCOMA; REACTIVE OXYGEN SPECIES; TRANSFECTION; UP-REGULATION;

EID: 3242667152     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Huang Q, Dunn RT 2nd, Jayadev S, DiSorbo O, Pack FD, Farr SB, Stoll RE and Blanchard KT: Assessment of cisplatin-induced nephrotoxicity by microarray technology. Toxicol Sci 63: 196-207, 2001.
2. Kartalou M and Essigmann JM: Mechanisms of resistance to cisplatin. Mutat Res 478: 23-43, 2001.
3. Colvin OM: Drug resistance in the treatment of sarcomas. Semin Oncol 24: 580-591, 1997.
4. Brabec V and Kasparkova J: Molecular aspects of resistance to antitumor platinum drugs. Drug Resist Updat 5: 147-161, 2002.
5. Norton JD and Atherton GT: Coupling of cell growth control and apoptosis functions of Id proteins. Mol Cell Biol 18: 2371-2381, 1998.
6. Norton JD, Deed RW, Craggs G and Sablitzky F: Id helix-loop-helix proteins in cell growth and differentiation. Trends Cell Biol 8: 58-65, 1998.
7. Massari ME and Murre C: Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol 20: 429-440, 2000.
8. Carmeliet P: Developmental biology. Controlling the cellular brakes. Nature 401: 657-658, 1999.
9. Riechmann V, van Cruchten I and Sablitzky F: The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res 22: 749-755, 1994.
10. Christy BA, Sanders LK, Lau LF, Copeland NG, Jenkins NA and Nathans D: An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proc Natl Acad Sci USA 88: 1815-1819, 1991.
11. Yates PR, Atherton GT, Deed RW, Norton JD and Sharrocks AD: Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors. EMBO J 18: 968-976, 1999.
12. Lasorella A, Noseda M, Beyna M, Yokota Y and Iavarone A: Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 407: 592-598, 2000.
13. Roberts EC, Deed RW, Inoue T, Norton JD and Sharrocks AD: Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding. Mol Cell Biol 21: 524-533, 2001.
14. Langlands K, Down GA and Kealey T: Id proteins are dynamically expressed in normal epidermis and dysregulated in squamous cell carcinoma. Cancer Res 60: 5929-5933, 2000.
15. Lin CQ, Singh J, Murata K, Itahana Y, Parrinello S, Liang SH, Gillett CE, Campisi J and Desprez PY: A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells. Cancer Res 60: 1332-1340, 2000.
16. Alani RM, Hasskarl J, Grace M, Hernandez MC, Israel MA and Munger K: Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1. Proc Natl Acad Sci USA 96: 9637-9641, 1999.
17. Facchini LM and Penn LZ: The molecular role of Myc in growth and transformation: recent discoveries lead to new insights. FASEB J 12: 633-651, 1998.
18. Raff MC: Social controls on cell survival and cell death. Nature 356: 397-400, 1992.
19. Kaufmann SH and Earnshaw WC: Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256: 42-49, 2000.
20. Itoh M, Chiba H, Noutomi T, Takada E and Mizuguchi J: Cleavage of Bax-alpha and Bcl-xL during carboplatin-mediated apoptosis in squamous cell carcinoma cell line. Oral Oncol 36: 277-285, 2000.
21. Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B and Kroemer G: Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182: 367-377, 1995.
22. Simon HU, Haj-Yehia A and Levi-Schaffer F: Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5: 415-418, 2000.
23. Susin SA, Zamzami N and Kroemer G: Mitochondria as regulators of apoptosis: doubt no more. Biochim Biophys Acta 1366: 151-165, 1998.
24. Suzuki H, Hotta T, Koyama T, Komagata M, Imakiire A, Yanase N, Yoshimoto T and Mizuguchi J: Retrovirus-mediated transduction of TRAIL and chemotherapeutic agents cooperatively induce apoptotic cell death in both sarcoma and myeloma cells. Anticancer Res 23: 3247-3253, 2003.
25. Nosaka T, Kawashima T, Misawa K, Ikuta K, Mui AL and Kitamura T: STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J 18: 4754-4765, 1999.
26. Yanase N, Ohshima K, Ikegami H and Mizuguchi J: Cytochrome c release, mitochondrial membrane depolarization, caspase-3 activation, and Bax-alpha cleavage during IFN-alpha-induced apoptosis in Daudi B lymphoma cells. J Interferon Cytokine Res 20: 1121-1129, 2000.
27. Hotta T, Suzuki H, Nagai S, Yamamoto K, Imakiire A, Takada E, Itoh M and Mizuguchi J: Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential. J Orthopaed Res 21: 949-957, 2003.
28. Christian MC: The current status of new platinum analogs. Semin Oncol 19: 720-733, 1992.
29. Reed JC: Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 11: 68-75, 1999.
30. Florio M, Hernandez MC, Yang H, Shu HK, Cleveland JL and Israel MA: Id2 promotes apoptosis by a novel mechanism independent of dimerization to basic helix-loop-helix factors. Mol Cell Biol 18: 5435-5444, 1998.
31. Deed RW, Bianchi SM, Atherton GT, Johnston D, Santibanez-Koref M, Murphy JJ and Norton JD: An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types. Oncogene 8: 599-607, 1993.
32. Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM and Murre C: Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nat Immunol 2: 165-171, 2001.