-
1
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999;104:155-62.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
2
-
-
0025879530
-
Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies
-
Bartek J, Bartkova J, Vojtesek B, Staskova Z, Lukas J, Rejthar A, et al. Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies. Oncogene 1991;6:1699-703.
-
(1991)
Oncogene
, vol.6
, pp. 1699-1703
-
-
Bartek, J.1
Bartkova, J.2
Vojtesek, B.3
Staskova, Z.4
Lukas, J.5
Rejthar, A.6
-
3
-
-
0035912109
-
Sensitization of resistant lymphoma, cells to irradiation-induced apoptosis by the death ligand TRAIL
-
Belka C, Schmid B, Marini P, Durand E, Rudner J, Faltin H, et al. Sensitization of resistant lymphoma, cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene 2001;20:2190-6.
-
(2001)
Oncogene
, vol.20
, pp. 2190-2196
-
-
Belka, C.1
Schmid, B.2
Marini, P.3
Durand, E.4
Rudner, J.5
Faltin, H.6
-
4
-
-
0034509426
-
Osteosarcomas and other cancers of bone
-
Bramwell VH. Osteosarcomas and other cancers of bone. Curr Opin Oncol 2000;12:330-6.
-
(2000)
Curr. Opin. Oncol.
, vol.12
, pp. 330-336
-
-
Bramwell, V.H.1
-
5
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
Brown JM, Wouters BG. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 1999;59:1391-9.
-
(1999)
Cancer Res.
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
6
-
-
2642702621
-
Inactivation of p53 in normal human cells increases G2/M arrest and sensitivity to DNA-damaging agents
-
Ceraline J, Deplanque G, Duclos B, Limacher JM, Hajri A, Noel F, et al. Inactivation of p53 in normal human cells increases G2/M arrest and sensitivity to DNA-damaging agents. Int J Cancer 1998;75:432-8.
-
(1998)
Int. J. Cancer
, vol.75
, pp. 432-438
-
-
Ceraline, J.1
Deplanque, G.2
Duclos, B.3
Limacher, J.M.4
Hajri, A.5
Noel, F.6
-
8
-
-
0026595636
-
Inactivation of p53 gene in human and murine osteosarcoma cells
-
Chandar N, Billig B, McMaster J, Novak J. Inactivation of p53 gene in human and murine osteosarcoma cells. Br J Cancer 1992; 65:208-14.
-
(1992)
Br. J. Cancer
, vol.65
, pp. 208-214
-
-
Chandar, N.1
Billig, B.2
McMaster, J.3
Novak, J.4
-
9
-
-
0030763251
-
Drug resistance in the treatment of sarcomas
-
Colvin OM. Drug resistance in the treatment of sarcomas. Semin Oncol 1997;24:580-91.
-
(1997)
Semin. Oncol.
, vol.24
, pp. 580-591
-
-
Colvin, O.M.1
-
10
-
-
0031974274
-
Mitochondria in chemotherapy-induced apoptosis: A prospective novel target of cancer therapy
-
(Review)
-
Decaudin D, Marzo II, Brenner C, Kroemer G. Mitochondria in chemotherapy-induced apoptosis: a prospective novel target of cancer therapy (Review). Int J Oncol 1998;12:141-52.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 141-152
-
-
Decaudin, D.1
Marzo A. II2
Brenner, C.3
Kroemer, G.4
-
11
-
-
0024427025
-
Adjuvant chemotherapy for osteosarcoma
-
Eilber FR, Rosen G. Adjuvant chemotherapy for osteosarcoma. Semin Oncol 1989;16:312-22.
-
(1989)
Semin. Oncol.
, vol.16
, pp. 312-322
-
-
Eilber, F.R.1
Rosen, G.2
-
12
-
-
0036605042
-
Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis
-
Evdokiou A, Bouralexis S, Atkins GJ, Chai F, Hay S, Clayer M, et al. Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis. Int J Cancer 2002;99:491-504.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 491-504
-
-
Evdokiou, A.1
Bouralexis, S.2
Atkins, G.J.3
Chai, F.4
Hay, S.5
Clayer, M.6
-
13
-
-
0031782909
-
TRAIL: A molecule with multiple receptors and control mechanisms
-
Griffith TS, Lynch DH. TRAIL: a molecule with multiple receptors and control mechanisms. Curr Opin Immunol 1998; 10:559-63.
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 559-563
-
-
Griffith, T.S.1
Lynch, D.H.2
-
14
-
-
0035523826
-
How melanoma cells evade trail-induced apoptosis
-
Hersey P, Zhang XD. How melanoma cells evade trail-induced apoptosis. Nature Rev Cancer 2001;1:142-50.
-
(2001)
Nature Rev. Cancer
, vol.1
, pp. 142-150
-
-
Hersey, P.1
Zhang, X.D.2
-
15
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-5.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
16
-
-
0347927488
-
Etoposide-mediated sensitization of squamous cell carcinoma cells of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced loss in mitochondrial membrane potential
-
Itoh M, Noutomi T, Toyota H, Mizuguchi J. Etoposide-mediated sensitization of squamous cell carcinoma cells of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced loss in mitochondrial membrane potential. Oral Oncol 2003;39:269-76.
-
(2003)
Oral Oncol.
, vol.39
, pp. 269-276
-
-
Itoh, M.1
Noutomi, T.2
Toyota, H.3
Mizuguchi, J.4
-
17
-
-
0033083990
-
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines
-
Keane MM, Ettenberg SA, Nau MM, Russell EK, Lipkowitz S. Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. Cancer Res 1999;59:734-41.
-
(1999)
Cancer Res.
, vol.59
, pp. 734-741
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nau, M.M.3
Russell, E.K.4
Lipkowitz, S.5
-
18
-
-
0037151079
-
An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
-
Kim Y, Suh N, Sporn M, Reed JC. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. J Biol Chem 2002;277:22320-9.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22320-22329
-
-
Kim, Y.1
Suh, N.2
Sporn, M.3
Reed, J.C.4
-
19
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000;12:611-20.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
20
-
-
0035866369
-
Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
-
Lacour S, Hammann A, Wotawa A, Corcos L, Solary E, Dimanche-Boitrel MT. Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res 2001;61:1645-51.
-
(2001)
Cancer Res.
, vol.61
, pp. 1645-1651
-
-
Lacour, S.1
Hammann, A.2
Wotawa, A.3
Corcos, L.4
Solary, E.5
Dimanche-Boitrel, M.T.6
-
21
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001; 104:487-501.
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
22
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, et al. p53 status and the efficacy of cancer therapy in vivo. Science 1994;266:807-10.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
-
23
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993;74:957-67.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
24
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM, et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995;182:1545-56.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1545-1556
-
-
Martin, S.J.1
Reutelingsperger, C.P.2
McGahon, A.J.3
Rader, J.A.4
van Schie, R.C.5
LaFace, D.M.6
-
25
-
-
0033523670
-
Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein
-
Medema JP, de Jong J, van Hall T, Melief CJ, Offringa R. Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein. J Exp Med 1999;190:1033-8.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1033-1038
-
-
Medema, J.P.1
de Jong, J.2
van Hall, T.3
Melief, C.J.4
Offringa, R.5
-
26
-
-
0036138282
-
Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
-
Mizutani Y, Nakanishi H, Yoshida O, Fukushima M, Bonavida B, Miki T. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur J Cancer 2002;39:167-76.
-
(2002)
Eur. J. Cancer
, vol.39
, pp. 167-176
-
-
Mizutani, Y.1
Nakanishi, H.2
Yoshida, O.3
Fukushima, M.4
Bonavida, B.5
Miki, T.6
-
27
-
-
0035970721
-
Nuclear and mitochondrial apoptotic pathways of p53
-
Moll UM, Zaika A. Nuclear and mitochondrial apoptotic pathways of p53. FEBS Lett 2001;493:65-9.
-
(2001)
FEBS Lett.
, vol.493
, pp. 65-69
-
-
Moll, U.M.1
Zaika, A.2
-
28
-
-
0034652486
-
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
-
Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK, Huang HJ. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res 2000;60:847-53.
-
(2000)
Cancer Res.
, vol.60
, pp. 847-853
-
-
Nagane, M.1
Pan, G.2
Weddle, J.J.3
Dixit, V.M.4
Cavenee, W.K.5
Huang, H.J.6
-
30
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996;271:12687-90.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
31
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999;11:68-75.
-
(1999)
Curr. Opin. Oncol.
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
32
-
-
17744376764
-
Mechanisms of mitochondrial membrane permeabilization
-
Reed JC, Kroemer G. Mechanisms of mitochondrial membrane permeabilization. Cell Death Differ 2000;7:1145.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1145
-
-
Reed, J.C.1
Kroemer, G.2
-
33
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17:1675-87.
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
-
35
-
-
0032526268
-
Apoptosis signaling by death receptors
-
Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME. Apoptosis signaling by death receptors. Eur J Biochem 1998; 254:439-59.
-
(1998)
Eur. J. Biochem.
, vol.254
, pp. 439-459
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Los, M.3
Wesselborg, S.4
Peter, M.E.5
-
36
-
-
0032522463
-
p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
-
Sheikh MS, Burns TF, Huang Y, Wu GS, Amundson S, Brooks KS, et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res 1998;58:1593-8.
-
(1998)
Cancer Res.
, vol.58
, pp. 1593-1598
-
-
Sheikh, M.S.1
Burns, T.F.2
Huang, Y.3
Wu, G.S.4
Amundson, S.5
Brooks, K.S.6
-
37
-
-
0030795866
-
L can differentially block chemotherapy-induced cell death
-
L can differentially block chemotherapy-induced cell death. Blood 1997; 90:1208-16.
-
(1997)
Blood
, vol.90
, pp. 1208-1216
-
-
Simonian, P.L.1
Grillot, D.A.2
Nunez, G.3
-
38
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 2000;12:599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
-
39
-
-
0035216008
-
TRAIL/Apo-2L: Mechanisms and clinical applications in cancer
-
Srivastava RK. TRAIL/Apo-2L: mechanisms and clinical applications in cancer. Neoplasia 2001;3:535-46.
-
(2001)
Neoplasia
, vol.3
, pp. 535-546
-
-
Srivastava, R.K.1
-
41
-
-
0035253561
-
Prevention of anti-IgM-induced apoptosis accompanying G1 arrest in B lymphoma cells overexpressing dominant-negative mutant form of c-Jun N-terminal kinase 1
-
Takada E, Toyota H, Suzuki J, Mizuguchi J. Prevention of anti-IgM-induced apoptosis accompanying G1 arrest in B lymphoma cells overexpressing dominant-negative mutant form of c-Jun N-terminal kinase 1. J Immunol 2001;166:1641-9.
-
(2001)
J. Immunol.
, vol.166
, pp. 1641-1649
-
-
Takada, E.1
Toyota, H.2
Suzuki, J.3
Mizuguchi, J.4
-
42
-
-
0035122478
-
Proteins expressed in osteosarcoma and serum levels as prognostic factors
-
Trieb K, Kotz R. Proteins expressed in osteosarcoma and serum levels as prognostic factors. Int J Biochem Cell Biol 2001;33:11-7.
-
(2001)
Int. J. Biochem. Cell Biol.
, vol.33
, pp. 11-17
-
-
Trieb, K.1
Kotz, R.2
-
44
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995;3:673-82.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
-
45
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald III ER, Jiang W, Meng R, Krantz ID, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997;17(III):141-3.
-
(1997)
Nat. Genet.
, vol.17
, Issue.3
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald E.R. III3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
-
46
-
-
0013583837
-
Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
-
Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 1999;59:2747-53.
-
(1999)
Cancer Res.
, vol.59
, pp. 2747-2753
-
-
Zhang, X.D.1
Franco, A.2
Myers, K.3
Gray, C.4
Nguyen, T.5
Hersey, P.6
|