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Volumn 5, Issue 4, 2004, Pages 508-518

Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands

(8) Mach, Ulrich R a Hackling, Anneke E a Perachon, Sylvie b Ferry, Sandrine b Wermuth, Camille G c Schwartz, Jean Charles d Sokoloff, Pierre d Stark, Holger a

a GOETHE UNIVERSITY (Germany)

b Laboratoire Bioprojet (France)

c UNIVERSITÉ DE STRASBOURG (France)

d CENTRE PAUL BROCA (France)

Author keywords

Antagonists; Dopamines; Radiopharmaceuticals; Schizophrenia; Tetrahydroisoquinoline

Indexed keywords

3 (4 IODOPHENYL) N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL]ACRYLAMIDE; ACRYLAMIDE DERIVATIVE; BP 897; CLOZAPINE; DOPAMINE 3 RECEPTOR BLOCKING AGENT; FAUC 365; HALOPERIDOL; IODOSULPIRIDE; ISOQUINOLINE DERIVATIVE; LIGAND; N [4 [2 (6 CYANO 1,2,3,4 TETRAHYDRO 2 ISOQUINOLINYL)ETHYL]CYCLOHEXYL] 4 QUINOLINECARBOXAMIDE; PIMOZIDE; SULPIRIDE; UNCLASSIFIED DRUG; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DRD3 PROTEIN, HUMAN; PIPERAZINE DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE;

ALKYLATION; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DRUG SELECTIVITY; IN VITRO STUDY; PRIORITY JOURNAL; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; DRUG POTENTIATION; HAMSTER; HUMAN; METABOLISM;

ANIMALS; CHO CELLS; CRICETINAE; HUMANS; LIGANDS; MOLECULAR STRUCTURE; PIPERAZINES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; TETRAHYDROISOQUINOLINES;

EID: 3242655533 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200300784 Document Type: Article

Times cited : (93)

References (41)

1
- 0030249397
- R. M. Huff, Cell Signal. 1996, 8, 453-459.
- (1996) Cell Signal. , vol.8 , pp. 453-459
- Huff, R.M.¹

2
- 0027974044
- D.M. Jackson, A. Westlind-Danielsson, Pharmacol. Ther. 1994, 64, 291-370.
- (1994) Pharmacol. Ther. , vol.64 , pp. 291-370
- Jackson, D.M.¹ Westlind-Danielsson, A.²

3
- 6844250767
- C. Missale, S. R. Nash, S. W. Robinson, M. Jaber, M. G. Caron, Physiol. Rev. 1998, 78, 189-225.
- (1998) Physiol. Rev. , vol.78 , pp. 189-225
- Missale, C.¹ Nash, S.R.² Robinson, S.W.³ Jaber, M.⁴ Caron, M.G.⁵

4
- 0026481115
- P. Seeman, Neuropsychopharmacology 1992, 7, 261-284.
- (1992) Neuropsychopharmacology , vol.7 , pp. 261-284
- Seeman, P.¹

5
- 0027336474
- R. A. Lahti, D. L. Evans, N. C. Stratman, L. M. Figur, Eur. J. Pharmacol. 1993, 236, 483-486.
- (1993) Eur. J. Pharmacol. , vol.236 , pp. 483-486
- Lahti, R.A.¹ Evans, D.L.² Stratman, N.C.³ Figur, L.M.⁴

6
- 18644386045
- J. A. Hendrix, S. J. Shimshock, G. M. Shutske, J. D. Tomer IV, K. J. Kapples, M. G. Palermo, T. J. Corbett, H. M. Vargas, S. Kafka, K. M. Brooks, L. Laws-Ricker, D. K. Lee, I. de Lannoy, M. Bordeleau, G. Rizkalla, J. Owolabi, R. K. Kamboj, ChemBioChem 2002, 3, 999-1009.
- (2002) ChemBioChem , vol.3 , pp. 999-1009
- Hendrix, J.A.¹ Shimshock, S.J.² Shutske, G.M.³ Tomer IV, J.D.⁴ Kapples, K.J.⁵ Palermo, M.G.⁶ Corbett, T.J.⁷ Vargas, H.M.⁸ Kafka, S.⁹ Brooks, K.M.¹⁰ Laws-Ricker, L.¹¹ Lee, D.K.¹² De Lannoy, I.¹³ Bordeleau, M.¹⁴ Rizkalla, G.¹⁵ Owolabi, J.¹⁶ Kamboj, R.K.¹⁷

7
- 0030790282
- L. Thorn, T. E. Ashmeade, V. J. Storey, C. Routledge, C. Reavill, Neuropharmacology 1997, 36, 787-792.
- (1997) Neuropharmacology , vol.36 , pp. 787-792
- Thorn, L.¹ Ashmeade, T.E.² Storey, V.J.³ Routledge, C.⁴ Reavill, C.⁵

8
- 0033595283
- M. Pilla, S. Perachon, F. Sautel, F. Garridol, A. Mann, C. G. Wermuth, J.-C. Schwartz, B. J. Everitt, P. Sokoloff, Nature 1999, 400, 371-375.
- (1999) Nature , vol.400 , pp. 371-375
- Pilla, M.¹ Perachon, S.² Sautel, F.³ Garridol, F.⁴ Mann, A.⁵ Wermuth, C.G.⁶ Schwartz, J.-C.⁷ Everitt, B.J.⁸ Sokoloff, P.⁹

9
- 0025179967
- P. Sokoloff, B. Giros, M. P. Martes, M. L. Bouthenet, J.-C. Schwartz, Nature 1990, 347 146-151.
- (1990) Nature , vol.347 , pp. 146-151
- Sokoloff, P.¹ Giros, B.² Martes, M.P.³ Bouthenet, M.L.⁴ Schwartz, J.-C.⁵

10
- 0027337821
- J.-C. Schwartz, D. Levesque, M. P. Martres, P. Sokoloff, Clin. Neuropharmacol. 1993, 16, 295-314.
- (1993) Clin. Neuropharmacol. , vol.16 , pp. 295-314
- Schwartz, J.-C.¹ Levesque, D.² Martres, M.P.³ Sokoloff, P.⁴

11
- 0034066880
- G. Stemp, T. Ashmeade, C. L. Branch, M. S. Hadley, A. J. Hunter, C. N. Johnson, D. J. Nash, K. M. Thewlis, A. K. Vong, N. E. Austin, P. Jeffrey, K. Y. Avenell, I. Boyfield, J. J. Hagan, D. N. Middlemiss, C. Reavill, G. J. Riley, C. Routledge, M. Wood, J. Med. Chem. 2000, 43, 1878-1885.
- (2000) J. Med. Chem. , vol.43 , pp. 1878-1885
- Stemp, G.¹ Ashmeade, T.² Branch, C.L.³ Hadley, M.S.⁴ Hunter, A.J.⁵ Johnson, C.N.⁶ Nash, D.J.⁷ Thewlis, K.M.⁸ Vong, A.K.⁹ Austin, N.E.¹⁰ Jeffrey, P.¹¹ Avenell, K.Y.¹² Boyfield, I.¹³ Hagan, J.J.¹⁴ Middlemiss, D.N.¹⁵ Reavill, C.¹⁶ Riley, G.J.¹⁷ Routledge, C.¹⁸ Wood, M.¹⁹

12
- 0037057547
- L. Bettinetti, K. Schlotter, H. Hubner, P. Gmeiner, J. Med. Chem. 2002, 45, 4594-4597.
- (2002) J. Med. Chem. , vol.45 , pp. 4594-4597
- Bettinetti, L.¹ Schlotter, K.² Hubner, H.³ Gmeiner, P.⁴

13
- 0037019828
- 3, see: a) A. E. Hackling, H. Stark, ChemBioChem 2002, 3, 946-961;
- (2002) ChemBioChem , vol.3 , pp. 946-961
- Hackling, A.E.¹ Stark, H.²

14
- 0035352417
- b) A. M. Crider, M. A. Scheideler, Mini Rev. Med. Chem. 2001, 1, 89-99;
- (2001) Mini Rev. Med. Chem. , vol.1 , pp. 89-99
- Crider, A.M.¹ Scheideler, M.A.²

15
- 0037278185
- c) R. R. Luedtke, R. H. Mach, Curr. Pharm. Des. 2003, 9, 643-671.
- (2003) Curr. Pharm. Des. , vol.9 , pp. 643-671
- Luedtke, R.R.¹ Mach, R.H.²

16
- 0023228572
- H. Wikstroem, J. H. Lii, N. L. Allinger, J. Med. Chem. 1987, 30, 1115-1120.
- (1987) J. Med. Chem. , vol.30 , pp. 1115-1120
- Wikstroem, H.¹ Lii, J.H.² Allinger, N.L.³

17
- 0020423168
- J. G. Cannon, J. A. Perez, R. K. Bhatnagar, J. P. Long, F. M. Sharabi, J. Med. Chem. 1982, 25, 1442-1446.
- (1982) J. Med. Chem. , vol.25 , pp. 1442-1446
- Cannon, J.G.¹ Perez, J.A.² Bhatnagar, R.K.³ Long, J.P.⁴ Sharabi, F.M.⁵

18
- 0033838517
- C. Reavill, S. G. Taylor, M. D. Wood, T. Ashmeade, N. E. Austin, K. Y. Avenell, I. Boyfield, C. L. Branch, J. Cilia, M. C. Coldwell, M. S. Hadley, A. J. Hunter, P. Jeffrey, F. Jewitt, C. N. Johnson, D. N. Jones, A. D. Medhurst, D. N. Middlemiss, D. J. Nash, G. J. Riley, C. Routledge, G. Stemp, K. M. Thewlis, B. Trail, A. K. Vong, J. J. Hagan, J. Pharmacol. Exp. Ther. 2000, 294, 1154-1165.
- (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 1154-1165
- Reavill, C.¹ Taylor, S.G.² Wood, M.D.³ Ashmeade, T.⁴ Austin, N.E.⁵ Avenell, K.Y.⁶ Boyfield, I.⁷ Branch, C.L.⁸ Cilia, J.⁹ Coldwell, M.C.¹⁰ Hadley, M.S.¹¹ Hunter, A.J.¹² Jeffrey, P.¹³ Jewitt, F.¹⁴ Johnson, C.N.¹⁵ Jones, D.N.¹⁶ Medhurst, A.D.¹⁷ Middlemiss, D.N.¹⁸ Nash, D.J.¹⁹ Riley, G.J.²⁰ more..

19
- 4544246979
- H. Stark, U. Mach, S. Ferry, P. Sokoloff, Arch. Pharm. 2002, 335 (Suppl. 1), 133.
- (2002) Arch. Pharm. , vol.335 , Issue.SUPPL. 1 , pp. 133
- Stark, H.¹ Mach, U.² Ferry, S.³ Sokoloff, P.⁴

20
- 0034864462
- B. Weber, E. Schlicker, P. Sokoloff, H. Stark, Br. J. Pharmacol. 2001, 133, 1243-1248.
- (2001) Br. J. Pharmacol. , vol.133 , pp. 1243-1248
- Weber, B.¹ Schlicker, E.² Sokoloff, P.³ Stark, H.⁴

21
- 0038579160
- E. Bézard, S. Ferry, U. Mach, H. Stark, L. Leriche, T. Boraud, C. Gross, P. Sokoloff, Nat. Med. 2003, 6, 762-767.
- (2003) Nat. Med. , vol.6 , pp. 762-767
- Bézard, E.¹ Ferry, S.² Mach, U.³ Stark, H.⁴ Leriche, L.⁵ Boraud, T.⁶ Gross, C.⁷ Sokoloff, P.⁸

22
- 0034072079
- A. Kugaya, M. Fujita, R. B. Innis, Ann. Nucl. Med. 2000, 14, 1-9.
- (2000) Ann. Nucl. Med. , vol.14 , pp. 1-9
- Kugaya, A.¹ Fujita, M.² Innis, R.B.³

23
- 0033579921
- N. E. Austin, K. Y. Avenell, I. Boyfield, C. L. Branch, M. C. Coldwell, M. S. Hadley, P. Jeffrey, A. Johns, C. N. Johnson, D. J. Nash, G. J. Riley, S. A. Smith, R. C. Stacey, G. Stemp, K. M. Thewlis, A. K. Vong, Bioorg. Med. Chem. Lett. 1999, 9, 179-184.
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 179-184
- Austin, N.E.¹ Avenell, K.Y.² Boyfield, I.³ Branch, C.L.⁴ Coldwell, M.C.⁵ Hadley, M.S.⁶ Jeffrey, P.⁷ Johns, A.⁸ Johnson, C.N.⁹ Nash, D.J.¹⁰ Riley, G.J.¹¹ Smith, S.A.¹² Stacey, R.C.¹³ Stemp, G.¹⁴ Thewlis, K.M.¹⁵ Vong, A.K.¹⁶

24
- 0002062801
- H. Azizian, C. Eaborn, A. Pidcock, J. Organomet. Chem. 1981, 215, 49-58.
- (1981) J. Organomet. Chem. , vol.215 , pp. 49-58
- Azizian, H.¹ Eaborn, C.² Pidcock, A.³

25
- 0009335974
- M. Krause, H. Stark, W. Schunack, J. Labell. Compd. Radiopharm. 1997, 39, 601-606.
- (1997) J. Labell. Compd. Radiopharm. , vol.39 , pp. 601-606
- Krause, M.¹ Stark, H.² Schunack, W.³

26
- 0031443518
- G. L. Grunewald, V. H. Dahanukar, T. M. Caldwell, K. R. Criscione, J. Med. Chem. 1997, 40, 3997-4005.
- (1997) J. Med. Chem. , vol.40 , pp. 3997-4005
- Grunewald, G.L.¹ Dahanukar, V.H.² Caldwell, T.M.³ Criscione, K.R.⁴

27
- 0022971222
- I. Lantos, D. Bhattacharjee, D. S. Eggleston, J. Org. Chem. 1986, 51, 4147-4150.
- (1986) J. Org. Chem. , vol.51 , pp. 4147-4150
- Lantos, I.¹ Bhattacharjee, D.² Eggleston, D.S.³

28
- 0027389208
- A. I. Meyers, R. H. Hutchings, Tetrahedron 1993, 49, 1807-1820.
- (1993) Tetrahedron , vol.49 , pp. 1807-1820
- Meyers, A.I.¹ Hutchings, R.H.²

29
- 4544268976
- Fraenkel, Zeimer, Biochem. Z. 1920, 110, 238.
- (1920) Biochem. Z , vol.110 , pp. 238
- Fraenkel¹ Zeimer²

30
- 0028136126
- K. Sumita, M. Koumori, S. Ohno, Chem. Pharm. Bull. 1994, 42, 1676-1678.
- (1994) Chem. Pharm. Bull. , vol.42 , pp. 1676-1678
- Sumita, K.¹ Koumori, M.² Ohno, S.³

31
- 0034699497
- L. A. van Vliet, N. Rodenhuis, H. Wikstrom, T. A. Pugsley, K. A. Serpa, L. T. Meltzer, T. G. Heffner, L. D. Wise, M. E. Lajiness, R. M. Huff, K. Svensson, G. R. Haenen, A. Bast, J. Med. Chem. 2000, 43, 3549-3557.
- (2000) J. Med. Chem. , vol.43 , pp. 3549-3557
- Van Vliet, L.A.¹ Rodenhuis, N.² Wikstrom, H.³ Pugsley, T.A.⁴ Serpa, K.A.⁵ Meltzer, L.T.⁶ Heffner, T.G.⁷ Wise, L.D.⁸ Lajiness, M.E.⁹ Huff, R.M.¹⁰ Svensson, K.¹¹ Haenen, G.R.¹² Bast, A.¹³

32
- 0024051958
- U. Scarponi, A. M. Lazzarini, R. Caprioli, R. Costiglione, D. Toti, Farmaco. Ed. Sci. 1988, 43, 575-596.
- (1988) Farmaco. Ed. Sci. , vol.43 , pp. 575-596
- Scarponi, U.¹ Lazzarini, A.M.² Caprioli, R.³ Costiglione, R.⁴ Toti, D.⁵

33
- 0023793228
- R. A. Glennon, N. A. Naimann, M. E. Pierson, M. Titeler, R. A. Lyon, E. Weisberg, Eur. J. Pharmacol. 1988, 154, 339-341.
- (1988) Eur. J. Pharmacol. , vol.154 , pp. 339-341
- Glennon, R.A.¹ Naimann, N.A.² Pierson, M.E.³ Titeler, M.⁴ Lyon, R.A.⁵ Weisberg, E.⁶

34
- 0033584162
- T. Dubuffet, A. Newmann-Tancredi, D. Lussac, V. Audionot, A. Loutz, Bioorg. Med. Chem. Lett. 1999, 14, 2059-2064.
- (1999) Bioorg. Med. Chem. Lett. , vol.14 , pp. 2059-2064
- Dubuffet, T.¹ Newmann-Tancredi, A.² Lussac, D.³ Audionot, V.⁴ Loutz, A.⁵

35
- 14444270602
- T. R. Elworthy, A. P. P. W. Ford, G. W. Bantle, D. J. Morgans, R. S. Ozer, J. Med. Chem. 1997, 40, 2674-2687.
- (1997) J. Med. Chem. , vol.40 , pp. 2674-2687
- Elworthy, T.R.¹ Ford, A.P.P.W.² Bantle, G.W.³ Morgans, D.J.⁴ Ozer, R.S.⁵

36
- 0002184470
- A. N. Kost, A. P. Stankevichus, Chem. Heterocycl. Compd. 1971, 7, 1208-1212.
- (1971) Chem. Heterocycl. Compd. , vol.7 , pp. 1208-1212
- Kost, A.N.¹ Stankevichus, A.P.²

37
- 0029795609
- G. L. Grunewald, V. H. Dahanukar, P. Ching, K. R. Criscione, J. Med. Chem. 1996, 39, 3539-3546.
- (1996) J. Med. Chem. , vol.39 , pp. 3539-3546
- Grunewald, G.L.¹ Dahanukar, V.H.² Ching, P.³ Criscione, K.R.⁴

38
- 0021823532
- F. Morlacchi, G. Trapani, V. Losacco, D. Armenise, Farmaco Ed. Sci. 1985, 40, 671-682.
- (1985) Farmaco Ed. Sci. , vol.40 , pp. 671-682
- Morlacchi, F.¹ Trapani, G.² Losacco, V.³ Armenise, D.⁴

39
- 0021691305
- D. T. Connor, P. C. Unangst, C. F. Schwender, R. J. Sorenson, M. E. Carethers, J. Heterocycl. Chem. 1984, 21, 1557-1559.
- (1984) J. Heterocycl. Chem. , vol.21 , pp. 1557-1559
- Connor, D.T.¹ Unangst, P.C.² Schwender, C.F.³ Sorenson, R.J.⁴ Carethers, M.E.⁵

40
- 0024328330
- N. M. Gray, B. K. Cheng, S. J. Mick, C. M. Lair, P. C. Contreras, J. Med. Chem. 1989, 32, 1242-1248.
- (1989) J. Med. Chem. , vol.32 , pp. 1242-1248
- Gray, N.M.¹ Cheng, B.K.² Mick, S.J.³ Lair, C.M.⁴ Contreras, P.C.⁵

41
- 0015861774
- Y. C. Cheng, W. H. Prusoff, Biochem. Pharmacol. 1973, 22, 3099-3108.
- (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
- Cheng, Y.C.¹ Prusoff, W.H.²

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