Hexa-acylation and KDO2-glycosylation determine the specific immunostimulatory activity of Neisseria meningitidis lipid a for human monocyte derived dendritic cells

Vaccine

Volumn 24, Issue 9, 2006, Pages 1291-1297

  Zughaier, Susu ^a   Agrawal, Sudhanshu ^a   Stephens, David S ^a,b   Pulendran, Bali ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Dendritic cell; LOS; Th response

Indexed keywords

B7 ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; CD83 ANTIGEN; CD86 ANTIGEN; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 5; INTERLEUKIN 6; LIPID A DERIVATIVE; MENINGOCOCCUS VACCINE; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ACYLATION; ARTICLE; BACTERIAL GENETICS; BACTERIUM MUTANT; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELL STIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DRUG ACTIVITY; DRUG EXPOSURE; DRUG PURIFICATION; DRUG STRUCTURE; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; MONOCYTE; NEISSERIA MENINGITIDIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; UPREGULATION; WILD TYPE;

ACYLATION; CARBOHYDRATE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERFERON TYPE II; INTERLEUKIN-5; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEISSERIA MENINGITIDIS;

EID: 32344443724     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.09.039     Document Type: Article

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