Fc receptors as determinants of allergic reactions

Trends in Immunology

Volumn 27, Issue 2, 2006, Pages 88-95

  Kraft, Stefan ^a   Novak, Natalija ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIBODY; CHIMERIC PROTEIN; FC EPSILON RECEPTOR 1 ANTIBODY; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN E RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE SYK INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; TYROSINE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ALLERGIC REACTION; BASOPHIL; CELL TYPE; CELLULAR DISTRIBUTION; DENDRITIC CELL; EOSINOPHIL; GLYCOSYLATION; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENCE; IMMUNOGLOBULIN AGGREGATE; IMMUNOMODULATION; IMMUNOREGULATION; INFLAMMATION; MAST CELL; MONOCYTE; NONHUMAN; PEANUT ALLERGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; PROTEIN SUBUNITS; RECEPTORS, FC; SIGNAL TRANSDUCTION;

EID: 32344433191     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2005.11.008     Document Type: Review

References (63)

1. A.B. Kay Allergy and allergic diseases. First of two parts N. Engl. J. Med. 344 2001 30 37
2. A.B. Kay Allergy and allergic diseases. Second of two parts N. Engl. J. Med. 344 2001 109 113
3. D. Vercelli Genetic regulation of IgE responses: Achilles and the tortoise J. Allergy Clin. Immunol. 116 2005 60 64
4. S.J. Galli Mast cells as 'tunable' effector and immunoregulatory cells: recent advances Annu. Rev. Immunol. 23 2005 749 786
5. G. Marone Mast cells and basophils: friends as well as foes in bronchial asthma? Trends Immunol. 26 2005 25 31
6. J.V. Ravetch, and L.L. Lanier Immune inhibitory receptors Science 290 2000 84 89
7. O. Malbec Negative regulation of mast cell proliferation by FcgammaRIIB Mol. Immunol. 38 2002 1295 1299
8. B.A. Wurzburg Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains Immunity 13 2000 375 385
9. T. Wan The crystal structure of IgE Fc reveals an asymmetrically bent conformation Nat. Immunol. 3 2002 681 686
10. N. Novak IgE receptors Curr. Opin. Immunol. 13 2001 721 726
11. R. Sitia, and I. Braakman Quality control in the endoplasmic reticulum protein factory Nature 426 2003 891 894
12. B. Albrecht Export of the high affinity IgE receptor from the endoplasmic reticulum depends on a glycosylation-mediated quality control mechanism J. Immunol. 165 2000 5686 5694
13. E. Fiebiger Cotranslational endoplasmic reticulum assembly of Fc{varepsilon}RI controls the formation of functional IgE-binding receptors J. Exp. Med. 201 2005 267 277
14. N. Novak Evidence for a differential expression of the FcepsilonRIgamma chain in dendritic cells of atopic and nonatopic donors J. Clin. Invest. 111 2003 1047 1056
15. D. Dombrowicz Allergy-associated FcRbeta is a molecular amplifier of IgE- and IgG-mediated in vivo responses Immunity 8 1998 517 529
16. E. Donnadieu A second amplifier function for the allergy-associated Fc(epsilon)RI-beta subunit Immunity 12 2000 515 523
17. E. Donnadieu Competing functions encoded in the allergy-associated F(c)epsilonRIbeta gene Immunity 18 2003 665 674
18. D. Sakurai Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo J. Immunol. 172 2004 2374 2381
19. S. Yamasaki The quantity and duration of FcRgamma signals determine mast cell degranulation and survival Blood 103 2004 3093 3101
20. H. Turner, and J.P. Kinet Signalling through the high-affinity IgE receptor Fc epsilonRI Nature 402 1999 B24 B30
21. T. Kawakami, and S.J. Galli Regulation of mast-cell and basophil function and survival by IgE Nat. Rev. Immunol. 2 2002 773 786
22. N. Novak FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro J. Allergy Clin. Immunol. 113 2004 949 957
23. S. Kraft Aggregation of the high-affinity IgE receptor Fc(epsilon)RI on human monocytes and dendritic cells induces NF-kappaB activation J. Invest. Dermatol. 118 2002 830 837
24. M. Yamaguchi IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions J. Exp. Med. 185 1997 663 672
25. C.S. Lantz IgE regulates mouse basophil Fc epsilon RI expression in vivo J. Immunol. 158 1997 2517 2521
26. N. Shaikh Mast cell Fc epsilonRI expression in the rat intestinal mucosa and tongue is enhanced during Nippostrongylus brasiliensis infection and can be up-regulated by in vivo administration of IgE J. Immunol. 158 1997 3805 3812
27. D. Macglashan IgE and FceRI regulation Clin. Rev. Allergy Immunol. 29 2005 49 60
28. S.S. Saini The relationship between serum IgE and surface levels of FcepsilonR on human leukocytes in various diseases: correlation of expression with FcepsilonRI on basophils but not on monocytes or eosinophils J. Allergy Clin. Immunol. 106 2000 514 520
29. T.A. Borkowski Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI J. Immunol. 167 2001 1290 1296
30. V.L. Ott, and J.C. Cambier Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention? J. Allergy Clin. Immunol. 106 2000 429 440
31. M. Daeron Fc receptor biology Annu. Rev. Immunol. 15 1997 203 234
32. H.R. Katz Inhibitory receptors and allergy Curr. Opin. Immunol. 14 2002 698 704
33. T. Takai Fc receptors and their role in immune regulation and autoimmunity J. Clin. Immunol. 25 2005 1 18
34. C.L. Kepley Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes J. Biol. Chem. 279 2004 35139 35149
35. I. Isnardi Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap J. Biol. Chem. 279 2004 51931 51938
36. D. Infuhr Molecular and cellular targets of anti-IgE antibodies Allergy 60 2005 977 985
37. K. Asai Regulation of mast cell survival by IgE Immunity 14 2001 791 800
38. J. Kalesnikoff Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival Immunity 14 2001 801 811
39. M. Kohno Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen Blood 105 2005 2059 2065
40. H. Milgrom Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group N. Engl. J. Med. 341 1999 1966 1973
41. D.Y. Leung Effect of anti-IgE therapy in patients with peanut allergy N. Engl. J. Med. 348 2003 986 993
42. R. Belostotsky, and H. Lorberboum-Galski Utilizing Fcepsilon-Bak chimeric protein for studying IgE-FcepsilonRI interactions Clin. Immunol. 110 2004 89 99
43. R. Belostotsky, and H. Lorberboum-Galski Apoptosis-inducing human-origin Fcepsilon-Bak chimeric proteins for targeted elimination of mast cells and basophils: a new approach for allergy treatment J. Immunol. 167 2001 4719 4728
44. S. Kraft Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo J. Exp. Med. 201 2005 385 396
45. C.L. Kepley Syk deficiency in nonreleaser basophils J. Allergy Clin. Immunol. 104 1999 279 284
46. B.M. Vonakis Src homology 2 domain-containing inositol 5′ phosphatase is negatively associated with histamine release to human recombinant histamine-releasing factor in human basophils J. Allergy Clin. Immunol. 108 2001 822 831
47. E.O. Meltzer An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment J. Allergy Clin. Immunol. 115 2005 791 796
48. F. Tsang, and W.S. Fred Wong Inhibitors of tyrosine kinase signaling cascade attenuated antigen challenge of guinea-pig airways in vitro Am. J. Respir. Crit. Care Med. 162 2000 126 133
49. W. Duan Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma Am. J. Respir. Crit. Care Med. 167 2003 185 192
50. Matsubara, S. et al. (2005) Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness. Am. J. Respir. Crit Care Med. DOI:10.1164/rccm.200503-361OC (http://ajrccm.atsjournals.org/)
51. M. Daeron The same tyrosine-based inhibition motif, in the intracytoplasmic domain of Fc gamma RIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation Immunity 3 1995 635 646
52. D. Zhu A chimeric human-cat fusion protein blocks cat-induced allergy Nat. Med. 11 2005 446 449
53. K. Zhang Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein J. Allergy Clin. Immunol. 114 2004 321 327
54. D. Zhu A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation Nat. Med. 8 2002 518 521
55. C.L. Kepley Negative regulation of FcepsilonRI signaling by FcgammaRII costimulation in human blood basophils J. Allergy Clin. Immunol. 106 2000 337 348
56. S.W. Tam A bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils Allergy 59 2004 772 780
57. C.L. Kepley FcepsilonRI-FcgammaRII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells Clin. Immunol. 108 2003 89 94
58. T. Yamada Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc gamma-Fc epsilon chimeric protein J. Biol. Chem. 278 2003 32818 32824
59. H. Kono Fc{gamma}RIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling Hum. Mol. Genet. 14 2005 2881 2892
60. S.J. Till Mechanisms of immunotherapy J. Allergy Clin. Immunol. 113 2004 1025 1034
61. H.M. Dijstelbloem Inflammation in autoimmunity: receptors for IgG revisited Trends Immunol. 22 2001 510 516
62. J. Bonventre Cytosolic phospholipase A2alpha reigns supreme in arthritis and bone resorption Trends Immunol. 25 2004 116 119
63. R. Lesourne Insufficient phosphorylation prevents Fc gamma RIIB from recruiting the SH2 domain-containing protein-tyrosine phosphatase SHP-1 J. Biol. Chem. 276 2001 6327 6336