IgE receptors

Current Opinion in Immunology

Volumn 13, Issue 6, 2001, Pages 721-726

  Novak, N ^a   Kraft, S ^a   Bieber, T ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT;

ALLERGIC DISEASE; ALLERGIC REACTION; ANTIGEN PRESENTING CELL; BETA CHAIN; CELL TYPE; EFFECTOR CELL; HUMAN; HYPERSENSITIVITY REACTION; INFLAMMATORY DISEASE; NONHUMAN; REGULATORY MECHANISM; REVIEW; RODENT; SIGNAL TRANSDUCTION;

EID: 0035546052     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(01)00285-0     Document Type: Review

References (59)

1. Molecular cloning of rat USF2 cDNA and characterization of splicing variants
2. Export of the high affinity IgE receptor from the endoplasmic reticulum depends on a glycosylation-mediated quality control mechanism
3. The relationship between serum IgE and surface levels of FcεR on human leukocytes in various diseases: Correlation of expression with FcεRI on basophils but not on monocytes or eosinophils
4. Functional consequences of FcεRIα up-regulation by IgE in human basophils
5. Structure of the human IgE-Fc Cε3-Cε4 reveals conformational flexibility in the antibody effector domains
6. Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα
7. Epitope analysis and primary structures of variable regions of anti-human FcεRI monoclonal antibodies, and expression of the chimeric antibodies fused with human constant regions
8. Mast cells and basophils
9. A second amplifier function for the allergy associated FcεRI-β subunit
10. Allergy-associated polymorphisms of the FcεRI β subunit do not impact its two amplification functions
11. Distinct aggregation of β- and γ-chains of the high-affinity IgE receptor on cross-linking
12. Regulation of IgE-receptor expression, IgE occupancy and secretory capacity of mast cells
13. Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma
14. IgE receptor-mediated release of nerve growth factor by mast cells
15. Selective down-regulation of high-affinity IgE receptor εFc(RI) α-chain messenger RNA among transcriptome in cord blood-derived versus adult peripheral blood-derived cultured human mast cells
16. Multiple defects in FcεRI signaling in Syk-deficient nonreleaser basophils and IL-3 induced recovery of Syk expression and secretion
17. Characteristics of the free cytosolic calcium timelag following IgE-mediated stimulation of human basophils: Significance for the nonreleasing basophil phenotype
18. Human neutrophils express the high-affinity receptor for immunoglobulin E (FcεRI): Role in asthma
19. Signal transduction by the high-affinity immunglobulin E receptor FcεRI: Coupling form to function
20. Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
21. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells
22. Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling
23. Interaction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase
24. Cross-correlation analysis of inner-leaflet-anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components
25. FcεRI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells
26. Detergent-resistant microdomains offer no refuge for proteins phosphorylated by the IgE receptor
27. Spontaneous phosphorylation of the receptor with high affinity for IgE in transfected fibroblasts
28. SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcεRI signaling
29. Tyrosine phosphorylation of the linker for activator of T cells in mast cells by stimulation with the high affinity IgE receptor
30. Involvement of HRS binding protein in IgE receptor-triggered exocytosis in RBL-2H3 mast cells
31. The role of sphingosine kinase in the signaling initiated at the high-affinity receptor for IgE εFc(RI) in mast cells
32. Differential sensitivity to acute cholesterol lowering of activation mediated via the high-affinity IgE receptor and Thy-1 glycoprotein
33. 2+ entry mechanism
34. Modulation of high-affinity IgE receptor expression in blood monocytes: Opposite effect of IL-4 and glucocorticoids
35. Regulation of FcεRI expression on human monocytic cells by ligand and IL-4
36. Engagement of FcεRI on human monocytes induces the production of IL-10 and prevents their differentiation in dendritic cells
37. Role of the high affinity immunoglobulin E receptor in bacterial translocation and intestinal inflammation
38. Murine models of inflammation: Role of CD23
39. DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13
40. Enhanced intestinal transepithelial antigen transport in allergic rats is mediated by IgE and CD23 (Fc(RII)
41. A microfilament formation inhibitor, cytochalasin strongly enhances the low-affinity Fcε receptor II (CD23) expression on the human monocyte-like cell line, U937
42. Lyprinol inhibits LTB4 production by human monocytes
43. Stimulation of eosinophil IgE low-affinity receptor leads to increased adhesion molecule expression and cell migration
44. Inhibition of IgE-dependent histamine release from human peripheral blood basophils by humanized Fab fragments that recognize the membrane proximal domain of the human FcεRI α-chain
45. Epitope analysis and primary structures of variable regions of anti-human FcεRI monoclonal antibodies, and expression of the chimeric antibodies fused with human constant regions
46. Monoclonal antibodies and synthetic peptides define the active site of FcεRI and a potential receptor antagonist
47. Omalizumab
48. Activating and inhibitory signaling in mast cells: New opportunities for therapeutic intervention?
49. No evidence for a role of FcγRIIB in suppression of in vivo antibody responses to erythrocytes by passively administered IgG
50. Immunologically mediated signaling in basophils and mast cells: Finding therapeutic targets for allergic diseases in the human FcvarεR1 signaling pathway
51. Immunology. Giving inhibitory receptors a boost
52. Inhibition of IgE-receptor interactions
53. Negative regulation of FcγRI signaling by Fc(RII costimulation in human blood basophils
54. IgE-mediated suppression of primary antibody responses in vivo
55. Minimal requirements for IgE-mediated regulation of surface FcεRI
56. Regulation of mast cell survival by IgE
57. Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and survival
58. Human eosinophils and human high affinity IgE receptor transgenic mouse eosinophlils express low levels of high affinity IgE receptor, but release IL-10 upon receptor activation
59. Essential role for Gab2 in the allergic response