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Volumn 45, Issue 6, 2006, Pages 929-931

Asymmetric organocatalytic Henry reaction

Author keywords

Alkaloids; Asymmetric catalysis; Henry reaction; Hydrogen bonds; Organocatalysis

Indexed keywords

ALDEHYDES; AROMATIC COMPOUNDS; CATALYSIS; CATALYSTS; HYDROGEN BONDS;

EID: 32044463560     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200503724     Document Type: Article
Times cited : (324)

References (46)
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    • during the preparation of this communication, others reported enantioselectivc organocatalytic reactions using an analogous catalyst: b) S. H. McCooey, S. J. Connon, Angew. Chem. 2005, 117, 6525-6528;
    • (2005) Angew. Chem. , vol.117 , pp. 6525-6528
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    • In solution, Cinchona alkaloids exist as a mixture of conformers mainly arising from rotation along the C8-C9 and C4′-C9 bonds: G. D. H. Dijkstra, R. M. Kellogg, H. Wynberg, J. S. Svendsen, I. Marko, K. B. Sharpless, J. Am. Chem. Soc. 1989, 111, 8069-8076; moreover, the flexible thiourea moiety adds further conformational complexity to the molecule.
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    • After submission of this manuscript, Nagasawa and co-workers reported the use of a guanidine thiourea catalyst for the asymmetric Henry reaction of aliphatic aldehydes: Y. Sohtome, Y. Hashimoto, K. Nagasawa, Adv. Synth. Catal. 2005, 347, 1643-1648.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.