Schizophrenia, antipsychotics and diabetes: Genetic aspects

European Psychiatry

Volumn 20, Issue SUPPL. 4, 2005, Pages

  Bellivier, F ^a,b  

^a HENRI MONDOR HOSPITAL   (France)

^b INSERM   (France)

Author keywords

Antipsychotics; Diabetes; Schizophrenia

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR; DOPAMINE 5 RECEPTOR; HISTAMINE H1 RECEPTOR; NEUROLEPTIC AGENT; SEROTONIN 2C RECEPTOR; TYROSINE 3 MONOOXYGENASE;

CHROMOSOME 11; CHROMOSOME 2P; CHROMOSOME 5; CHROMOSOME 6Q; COMORBIDITY; CONFERENCE PAPER; DISEASE ASSOCIATION; GENE LOCUS; GENETIC ASSOCIATION; GENETICS; GLYCEMIC CONTROL; HUMAN; IATROGENIC DISEASE; LINKAGE ANALYSIS; NEUROCHEMISTRY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK ASSESSMENT; SCHIZOPHRENIA;

CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 6; COMORBIDITY; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IATROGENIC DISEASE; LINKAGE (GENETICS); RECEPTORS, ADRENERGIC, BETA-3; RECEPTORS, HISTAMINE H1; RECEPTORS, SEROTONIN; SCHIZOPHRENIA; TYROSINE 3-MONOOXYGENASE;

EID: 31944433436     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-9338(05)80187-7     Document Type: Conference Paper

References (51)

1. Allison D.B., and Casey D.E. Antipsychotic-induced weight gain: a review of the literature J Clin Psychiatry 62 Suppl 7 2001 22 31
2. Aschauer H.N., Fischer G., Isenberg K.E., Meszaros K., and Willinger U. No proof of linkage between schizophrenia-related disorders including schizophrenia and chromosome 2g21 region Eur Arch Psychiatry Clin Neurosci 243 1993 193 198
3. Asherson P., Mant R., Williams N., Cardno A., and Jones L. A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder Mot Psychiatry 3 1998 310 320
4. Blackwood D.H., He L., Morris S.W., McLean A., and Whitton C. A locus for bipolar affective disorder on chromosome 4p Nat Genet 12 1996 427 430
5. Blasi C., Pierelli F., Rispoli E., Saponara M., Vingolo E., and Andreani D. Wolfram's syndrome: a clinical, diagnostic, and interpretative contribution Diabetes Care 9 1986 521 528
6. Cheta D., Dumitrescu C., Georgescu M., Cocioaba G., and Lichiardopol R. A study on the types of diabetes mellitus in first degree relatives of diabetic patients Diabete Metab 16 1990 11 15
7. Chiba M., Suzuki S., Hinokio Y., Hirai M., and Satoh Y. Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder Metabolism 49 2000 1145 1149
8. Collier D.A., Barrett T.G., Curtis D., Macleod A., and Arranz M.J. Linkage of Wolfram syndrome to chromosome 4p16.1 and evidence for heterogeneity Am J Hum Genet 59 1996 855 863
9. Collin G.B., Marshall J.D., Cardon L.R., and Nishina P.M. Homozygosity mapping at Alstrom syndrome to chromosome 2p Hum Mot Genet 6 1997 213 219
10. Crow T.J., DeLisi L.E., and Johnstone E.C. Concordance by sex in sibling pairs with schizophrenia is paternally inherited. Evidence for a pseudoautosomal locus Br J Psychiatry 155 1989 92 97
11. DeLisi L.E., Shaw S.H., Crow T.J., Shields G., and Smith A.B. A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder Am J Psychiatry 159 2002 803 812
12. Demenais F., Kanninen T., Lindgren C.M., Wiltshire S., and Gaget S. A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes Hum Mot Genet 12 2003 1865 1873
13. Dynes J.B. Diabetes in schizophrenia and diabetes in nonpsychotic medical patients Dis New Syst 30 1969 341 344
14. Ekelund J., Lichtermann D., Hovatta I., Ellonen P., and Suvisaari J. Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22 Hum Mot Genet 12 9 2000 1049 1057
15. Eubanks J.H., Altherr M., Wagner-McPherson C., McPherson J.D., Wasmuth J.J., and Evans G.A. Localization of the D5 dopamine receptor gene to human chromosome 4p15.1-p15.3, centromeric to the Huntington's disease locus Genomics 12 1992 510 516
16. Evans K.L., Lawson D., Meitinger T., Blackwood D.H., and Porteous D.J. Mutational analysis of the Wolfram syndrome gene in two families with chromosome 4p-linked bipolar affective disorder Am J Med Genet 96 2000 158 160
17. Faraone S.V., Matise T., Svrakic D., Pepple J., and Malaspina D. Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium Am J Med Genet 81 1998 290 295
18. Freedman R., Coon H., Myles-Worsley M., Orr-Urtreger A., and Olincy A. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus Proc Natl Acad Sci USA 94 1997 587 592
19. Fujisawa T., Ikegami H., Yamato E., Takekawa K., and Nakagawa Y. Association of Trp64Arg mutation of the beta3-adrenergic-receptor with NIDDM and body weight gain Diabetologia 39 1996 349 352
20. Goudie A.J., Halford J.C., Dovey T.M., Cooper G.D., and Neill J.C. H(1)histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs Neuropsychopharmacology 28 2003 2209
21. Hager J., Dina C., Francke S., Dubois S., and Houari M. A genomewide scan for human obesity genes reveals a major susceptibility locus on chromosome 10 Nat Genet 20 1998 304 308
22. Hovatta I., Varilo T., Suvisaari J., Terwilliger J.D., and Ollikainen V. A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci Am J Hum Genet 65 1999 1114 1124
23. Inoue H., Tanizawa Y., Wasson J., Behn P., and Kalidas K. A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) Nat Genet 20 1998 143 148
24. Kaneda Y., Fujii A., and Ohmori T. The hypothalamic-pituitary-adrenal axis in chronic schizophrenic patients long-term treated with neuroleptics Prog Neuropsychopharmacol Biol Psychiatry 26 5 2002 935 938
25. Kaufmann C.A., Suarez B., Malaspina D., Pepple J., and Svrakic D. NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees Am J Med Genet 81 1998 282 289
26. Kendler K.S., Gruenberg A.M., and Kinney D.K. Independent diagnoses of adoptees and relatives as defined by DSM-III in the provincial and national samples of the Danish Adoption Study of Schizophrenia Arch Gen Psychiatry 51 1994 456 468
27. Kikuchi M., Yamada K., Toyota T., Itokawa M., and Hattori E. Two-step association analyses of the chromosome 18p11.2 region in schizophrenia detect a locus encompassing C18orf1 Mol Psychiatry 8 2003 467 469
28. Kopecky J., Flachs P., Bardova K., Branner P., Prazak T., and Sponarova J. Modulation of lipid metabolism by energy status of adipocytes:implications for insulin sensitivity Ann N Y Acad Sci 967 2002 88 101
29. Kroeze W.K., Hufeisen S.J., Popadak B.A., Renock S.M., Steinberg S., Ernsberger P., Jayathilake K., Meltzer H.Y., and Roth B.L. H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs Neuropsychopharmacology 28 2003 519 526
30. Lin M.W., Curtis D., Williams N., Arranz M., and Nanko S. Suggestive evidence for linkage of schizophrenia to markers on chromosome 13814.1-q32 Psychiatr Genet 5 1995 117 126
31. Lorenz W.F. Sugar tolerance in dementia praecox and other mental disorders Arch Neurol Psychiatry 8 1922 184 196
32. McGuffin P., Tandon K., and Corsico A. Linkage and association studies of schizophrenia Curr Psychiatry Rep 5 2003 121 127
33. McIntyre E.A., and Walker M. Genetics of type 2 diabetes and insulin resistance: knowledge from human studies Clin Endocrinol 57 2002 303 311
34. Mitchell B.D., Cole S.A., Hsueh W.C., Comuzzie A.G., and Blangero J. Linkage of serum insulin concentrations to chromosome 3p in Mexican Americans Diabetes 49 2000 513 516
35. Mukherjee S., Schur D.B., and Reddy R. Family history of type 2 diabetes in schizophrenic patients Lancet 333 1989 495
36. Pulver A.E., Karayiorgou M., Wolyniec P.S., Lasseter V.K., and Kasch L. Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1 Am J Med Genet 54 1994 36 43
37. Pulver A.E., Lasseter V.K., Kasch L., Wolyniec P., and Nestadt G. Schizophrenia: a genome scan targets chromosomes 3p and 8p as potential sites of susceptibility genes Am J Med Genet 60 1995 252 260
38. Regenold W.T., Thapar R.K., Marano C., Gavirneni S., and Kondapavuluru P.V. Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use J Affect Disord 70 2002 19 26
39. Riley B.P., and Williamson R. Non-parametric analysis of chromosome 6p24-22 marker data and schizophrenia in southern African Bantuspeaking families Psychiatr Genet 7 1997 131 132
40. Ryan M.C.M., Collins P., and Thakore J.H. Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia Am J Psychiatry 160 2003 284 289
41. Sernyak M.J., Leslie D.L., Alarcon R.D., Losonczy M.F., and Rosenheck R. Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia Am J Psychiatry 159 2002 561 566
42. Shayegan D.K., and Stahl S.M. Atypical antipsychotics: matching receptor profile to individual patient's clinical profile CNS Spear 910 Suppl 11 2004 6 14
43. Sten-Linder M., Wedell A., Iselius L., Efendic S., Luft R., and Luthman H. DNA polymorphisms in the human tyrosine hydroxylase/insulin/ insulin-like growth factor II chromosomal region in relation to glucose and insulin responses Diabetologia 36 1993 25 32
44. Tabata H., Kikuoka M., Kikuoka H., Bessho H., and Hirayama J. Characteristics of diabetes mellitus in schizophrenic patients J Med Assoc Thai 70 Suppl 2 1987 90 93
45. Tecott L.H., Sun L.M., Akana S.F., Strack A.M., and Lowenstein D.H. Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors Nature 374 1995 542 546
46. Tejedor-Real P., Faucon Biguet N., Dumas S., and Mallet J. Tyrosine hydroxylase mRNA and protein are down-regulated by chronic clozapine in both the mesocorticolimbic and the nigrostriatal systems J Neurosci Res 72 1 2003 105 115
47. Torres R., Leroy E., Hu X., Katrivanou A., and Gourzis P. Mutation screening of the Wolfram syndrome gene in psychiatric patients Mol Psychiatry 6 2001 39 43
48. Wang S., Sun C.E., Walczak C.A., Ziegle J.S., and Kipps B.R. Evidence for a susceptibility locus for schizophrenia on chromosome 6pter-p22 Nat Genet 10 1995 41 46
49. Williams N.M., Rees M.I., Holmans P., Norton N., and Cardno A.G. A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs Hum Mol Genet 8 1999 1729 1739
50. Wolford J.K., Gruber J.D., Ossowski V.M., Vozarova B., and Antonio Tataranni P. A C-reactive protein promoter polymorphism is associated with type 2 diabetes mellitus in Pima Indians Mol Genet Metab 78 2003 136 144
51. Wolford J.K., Konheim Y.L., Colligan P.B., and Bogardus C. Association of a F479L variant in the cytosolic phospholipase A2 gene (PLA2G4A) with decreased glucose turnover and oxidation rates in Pima Indians Mol Genet Metab 79 2003 61 66