Tyrosine hydroxylase mRNA and protein are down-regulated by chronic clozapine in both the mesocorticolimbic and the nigrostriatal systems

Journal of Neuroscience Research

Volumn 72, Issue 1, 2003, Pages 105-115

  Tejedor Real, Purificación ^a,b   Faucon Biguet, Nicole ^a   Dumas, Sylvie ^a   Mallet, Jacques ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b UNIVERSITY OF CÁDIZ   (Spain)

Author keywords

Clozapine; Mesocorticolimbic system; Nigrostriatal system; Schizophrenia; Tyrosine hydroxylase

Indexed keywords

CLOZAPINE; DOPAMINE; MESSENGER RNA; NEUROLEPTIC AGENT; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE METABOLISM; DOPAMINERGIC SYSTEM; DOWN REGULATION; IN SITU HYBRIDIZATION; MALE; MESOCORTICOLIMBIC SYSTEM; NERVE ENDING; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCHIZOPHRENIA; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM; WESTERN BLOTTING;

ANIMALS; CLOZAPINE; CORPUS STRIATUM; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIMBIC SYSTEM; MALE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE; VENTRAL TEGMENTAL AREA;

EID: 0037380110     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10555     Document Type: Article

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