Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype

Journal of Inherited Metabolic Disease

Volumn 28, Issue 6, 2005, Pages 1065-1080

  de Voer, G ^a   van Bent, P ^a   Rodrigues, A J G ^b   van Ommen, G J B ^a   Peters, D J M ^a   Taschner, P E M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF MINHO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GREEN FLUORESCENT PROTEIN; PROTEIN CLN3; UNCLASSIFIED DRUG;

ARTICLE; BROOD PARASITISM; CAENORHABDITIS ELEGANS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MODEL; EGG LAYING; ELECTRON MICROSCOPY; GENE DELETION; GENE FUSION; GENE MUTATION; LIFESPAN; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREMATURE AGING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION; VISUAL IMPAIRMENT; YEAST;

ALLELES; ANIMALS; CAENORHABDITIS ELEGANS; CARBOHYDRATE METABOLISM; COSMIDS; DISEASE MODELS, ANIMAL; DNA PRIMERS; FEMALE; GENE DELETION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; LYSOSOMES; MALE; MEMBRANE GLYCOPROTEINS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; MODELS, STATISTICAL; MOLECULAR CHAPERONES; MUTATION; MUTATION, MISSENSE; NEURODEGENERATIVE DISEASES; NEURONAL CEROID-LIPOFUSCINOSES; NEURONS; PHENOTYPE; PROGERIA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TIME FACTORS; TRANSGENES;

EID: 31644449018     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-005-0125-7     Document Type: Article

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