Nuclear protein NP60 regulates p38 MAPK activity

Journal of Cell Science

Volumn 119, Issue 1, 2006, Pages 115-123

  Fu, Jing ^a   Yang, Ziqiang ^a   Wei, Jinxue ^a   Han, Jiahuai ^b   Gu, Jun ^a  

^a PEKING UNIVERSITY   (China)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

NP60; P38 phosphorylation; Signaling; Sorbitol

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; NUCLEAR PROTEIN; SORBITOL; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CELL NUCLEUS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENES, REPORTER; HUMANS; INDICATORS AND REAGENTS; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SORBITOL;

EID: 31644442352     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02699     Document Type: Article

References (32)

1. Aravind, L. and Landsman, D. (1998). AT-hook motifs identified in a wide variety of DNA-binding proteins. Nucleic Acids Res. 26, 4413-4421.
2. Brancho, D., Tanaka, N., Jaeschke, A., Ventura, J. J., Kelkar, N., Tanaka, Y., Kyuuma, M., Takeshita, T., Flavell, R. A. and Davis, R. J. (2003). Mechanism of p38 MAP kinase activation in vivo. Genes Dev. 17, 1969-1978.
3. Cuenda, A., Alonso, G., Morrice, N., Jones, M., Meier, R., Cohen, P. and Nebreda, A. R. (1996). Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. EMBO J. 15, 4156-4164.
4. Davis, R. J. (1993). The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268, 14553-14556.
5. Davis, R. J. (2000). Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252.
6. Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R. J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
7. Derijard, B., Raingeaud, J., Barrett, T., Wu, I. H., Han, J., Ulevitch, R. J. and Davis, R. J. (1995). Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267, 682-685.
8. Fanger, G. R., Gerwins, P., Widmann, C., Jarpe, M. B. and Johnson, G. L. (1997). MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? Curr. Opin. Genet. Dev. 7, 67-74.
9. Ge, B., Gram, H., Di Padova, F., Huang, B., New, L., Ulevitch, R. J., Luo, Y. and Han, J. (2002). MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. Science 295, 1291-1294.
10. Ge, B., Xiong, X., Jing, Q., Mosley, J. L., Filose, A., Bian, D., Huang, S. and Han, J. (2003). TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1. J. Biol. Chem. 278, 2286-2293.
11. Han, J., Lee, J. D., Tobias, P. S. and Ulevitch, R. J. (1993). Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J. Biol. Chem. 268, 25009-25014.
12. Han, J., Lee, J. D., Bibbs, L. and Ulevitch, R. J. (1994). A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811.
13. Han, J., Lee, J. D., Jiang, Y., Li, Z., Feng, L. and Ulevitch, R. J. (1996). Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem. 271, 2886-2891.
14. Kayali, A. G., Austin, D. A. and Webster, N. J. (2000). Stimulation of MAPK cascades by insulin and osmotic shock: lack of an involvement of p38 mitogen-activated protein kinase in glucose transport in 3T3-L1 adipocytes. Diabetes 49, 1783-1793.
15. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Abroad, M. F., Avruch, J. and Woodgett, J. R. (1994). The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
16. Marcus, S., Polverino, A., Barr, M. and Wigler, M. (1994). Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc. Natl. Acad. Sci. USA 91, 7762-7766.
17. Moriguchi, T., Toyoshima, F., Gotoh, Y., Iwamatsu, A., Irie, K., Mori, E., Kuroyanagi, N., Hagiwara, M., Matsumoto, K. and Nishida, E. (1996). Purification and identification of a major activator for p38α from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2. J. Biol. Chem. 271, 26981-26988.
18. New, L., Jiang, Y. and Han, J. (2003). Regulation of PRAK subcellular location by p38α MAP kinases. Mol. Biol. Cell 14, 2603-2616.
19. Ono, K. and Han, J. (2000). The p38 signal transduction pathway: activation and function. Cell Signal 12, 1-13.
20. Pearson, G., Robinson, F., Beers Gibson, T., Xu, B. E., Karandikar, M., Berman, K. and Cobb, M. H. (2001). Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22, 153-183.
21. Posas, F. and Saito, H. (1997). Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276, 1702-1705.
22. Qiu, C., Sawada, K., Zhang, X. and Cheng, X. (2002). The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds. Nat. Struct. Biol. 9, 217-224.
23. Raingeaud, J., Whitmarsh, A. J., Barrett, T., Derijard, B. and Davis, R. J. (1996). MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16, 1247-1255.
24. Robinson, M. J. and Cobb, M. H. (1997). Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 9, 180-186.
25. Sambrook, J., Fritch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press.
26. Schaeffer, H. J., Catling, A. D., Eblen, S. T., Collier, L. S., Krauss, A. and Weber, M. J. (1998). MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science 281, 1668-1671.
27. Seternes, O. M., Johansen, B., Hegge, B., Johannessen, M., Keyse, S. M. and Moens, U. (2002). Both binding and activation of p38α mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress. Mol. Cell. Biol. 22, 6931-6945.
28. Stec, I., Nagl, S. B., van Ommen, G. J. and den Dunnen, J. T. (2000). The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation? FEBS Lett. 473, 1-5.
29. Su, B. and Karin, M. (1996). Mitogen-activated protein kinase cascades and regulation of gene expression. Curr. Opin. Immunol. 8, 402-411.
30. Uhlik, M. T., Abell, A. N., Johnson, N. L., Sung W., Cuevas, B. D., Lobel-Rice, K. E., Horne, E. A., Dell'Acqua, M. L. and Johnson, G. L. (2003). Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat. Cell. Biol. 5, 1104-1110.
31. Whitmarsh, A. J., Cavanagh, J., Tournier, C., Yasuda, J. and Davis, R. J. (1998). A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281, 1671-1674.
32. Yu, J. Y., DeRuiter, S. L. and Turner, D. L. (2002). RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad Sci. USA 99, 6047-6052.