A suppressive effect of the adenovirus 5 protein E1B 55K on apoptosis induced by IL-3 deprivation and γ-irradiation

Biology of the Cell

Volumn 94, Issue 2, 2002, Pages 77-89

  Jilani, Kamal Eddine Ben ^a   Gaillard, Jean Philippe ^a,c   Petit, Frédéric ^a   Arnoult, Damien ^a   Roumier, Anne Sophie ^b   Labalette, Myriam ^b   Ameisen, Jean Claude ^a   Estaquier, Jérôme ^a  

^a INSERM   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Bcl 2; Cell death; Cytokine; E1B 55K; Mitochondria

Indexed keywords

CASPASE; CASPASE INHIBITOR; DNA; DNA FRAGMENT; INTERLEUKIN 3; PHOSPHATIDYLSERINE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; VIRUS PROTEIN;

ADENOVIRUS 5; ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CULTURE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL SURVIVAL; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; GAMMA IRRADIATION; GENE INACTIVATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; INHIBITION KINETICS; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOSIS; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; VIRUS TYPING;

ADENOVIRUS E1B PROTEINS; ANIMALS; APOPTOSIS; CELL CYCLE; GAMMA RAYS; GENETIC VECTORS; INTERLEUKIN-3; KINETICS; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; MYELOID CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROVIRIDAE;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 5; MURINAE;

EID: 0036589884     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0248-4900(02)01184-X     Document Type: Article

References (55)

1. Adams, J.M., Cory, S., 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322-1326.
2. Ameisen, J.C., 1994. Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer. AIDS 8, 1197-1213.
3. Ameisen, J.C., Estaquier, J., Idziorek, T., 1994. From AIDS to parasite infection: pathogen-mediated subversion of programmed cell death as a mechanism for immune dysregulation. Immunol. Rev. 142, 9-51.
4. Antoku, K., Liu, Z., Johnson, D.E., 1998. IL-3 withdrawal activates a crmA-insensitive poly(ADP-ribose) polymerase cleavage enzyme in factor-dependent myeloid progenitor cells. Leukemia 12, 682-689.
5. Barge, R.M., Willemze, R., Vandenabeele, P., Fiers, W., Beyaert, R., 1997. Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal. FEBS Lett. 409, 207-210.
6. Barker, D.D., Berk, A.J., 1987. Adenovirus proteins from both E1B proteins are required for transformation of rodent cells by viral infection and DNA transfection. Virology 156, 107-121.
7. Bates, S., Vousden, K.H., 1996. p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. 6, 12-18.
8. Blandino, G., Scardigli, R., Rizzo, M.G., Crescenzi, M., Soddu, S., Sacchi, A., 1995. Wild-type p53 modulates apoptosis of normal, IL-3 deprived, hematopoietic cells. Oncogene 4, 731-737.
9. Boise, L.H., Gonzalez-Garcia, M., Postema, C.E., Ding, L., Lindsten, T., Turka, L.A., Mao, X., Nunez, G., Thompson, C.B., 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74, 597-608.
10. Bos, J.L., Polder, L.J., Bernards, R., Schrier, P.I., Van Den Eisen, P.J., Van Der Eb, A.J., Van Hormondt, H., 1981. The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets. Cell 27, 121-131.
11. Canman, C.E., Gilmer, T.M., Coutts, S.B., Kastan, M.B., 1995. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev. 9, 600-611.
12. Chao, C., Saito, S., Anderson, C.W., Appella, E., Xu, Y, 2000. Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage. Proc. Natl. Acad. Sci. USA 97, 11936-11941.
13. Chehab, N.H., Malikzay, A., Stavridi, E.S., Halazonetis, T.D., 1999. Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc. Natl. Acad. Sci. USA 96, 13777-13782.
14. Chen, G., Branton, P.E., Yang, E., Korsmeyer, S.J., Shore, G.C., 1996. Adenovirus E1B 19kDa death suppressor protein interacts with Bax but not with Bad. J. Biol. Chem. 271, 24221-24224.
15. Cropton, T., 1990. IL-3 dependent cells die by apoptosis on removal of their growth factor. Growth Factors 4, 109-116.
16. Estaquier, J., Idziorek, T., De Bels, F., Barré-Sinoussi, F., Hurtrel, B., Aubertin, A.M., Venet, A., Mehtali, M., Muchmore, E., Michel, P., Mouton, Y., Girard, M., Ameisen, J.C., 1994. Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc. Natl. Acad. Sci. USA 91, 9431-9435.
17. Estaquier, J., Idziorek, T., Zou, W., Emilie, D., Farber, C.M., Bourez, J.M., Ameisen, J.C., 1995. Th1/Th2 cytokines and T-cell death: preventive effect of IL-12 on activation-induced and CD95 (Fas/Apo-1)-mediated apoptosis of CD4+ T cells from HIV-infected persons. J. Exp. Med. 182, 1759-1767.
18. Estaquier, J., Monceaux, V., Cumont, M.C., Aubertin, A.M., Hurtrel, B., Ameisen, J.C., 2000. Early changes in peripheral blood T cells during primary infection of rhesus macaques with a pathogenic SIV. J. Med. Primatol. 29, 127-135.
19. + T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists. Blood 87, 4959-4966.
20. Gottlieb, E., Haffner, R., Von Ruden, T., Wagner, E.F., Oren, M., 1994. Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J. 13, 1368-1374.
21. Gottlieb, E., Linder, S., Oren, M., 1996. Relationship of sequence-specific transactivation and p53-regulated apoptosis in interleukin 3-dependent hematopoietic cells. Cell Growth Differentiation 7, 301-310.
22. Green, D., Kroemer, G., 1998. The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol. 8, 267-271.
23. Gross, A., Jockel, J., Wei, M.C., Korsmeyer, S.J., 1998. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 14, 3878-3885.
24. Hashimoto, S., Ishii, A., Yonehara, S., 1991. The E1B oncogene of adenovirus confers cellular resistance to cytotoxicity of tumor necrosis factor and monoclonal anti-Fas antibody. Int. Immunol. 3, 343-351.
25. Haupt, Y., Maya, R., Kazaz, A., Oren, M., 1997. Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
26. Jacobson, M., Weil, M., Raff, M.C., 1997. Programmed cell death in animal development. Cell 88, 347-354.
27. Jurgensmeier, J.M., Xie, Z., Deveraux, Q., Ellerby, L., Bredesen, D., Reed, J.C., 1998. Bax directly induces release of cytochrome c from isolated mitochondria. Proc. Natl. Acad. Sci USA 95, 4997-5002.
28. Kubbutat, M.H., Jones, S.N., Vousden, K.H., 1997. Regulation of p53 stability by Mdm2. Nature 387, 299-303.
29. Lotem, J., Sachs, L., 1993. Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood 82, 1092-1096.
30. Martin, S.J., Green, D.R., 1995. Protease activation during apoptosis: death by a thousand cuts? Cell 82, 349-352.
31. Martinou, I., Fernandez, P.A., Missotten, M., White, E., Allet, B., Sadoul, R., Martinou, J.C., 1995. Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation. J. Cell Biol. 128, 201-208.
32. Mazel, S., Burtrum, D., Petrie, H., 1996. Regulation of cell cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J Exp. Med. 183, 2219-2226.
33. Miyashita, T., Reed, J.C., 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.
34. Nunez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J.P., Korsmeyer, S.J., 1990. Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144, 3602-3610.
35. O'Brian, V., 1998. Viruses and apoptosis. J. Gen. Virol. 79, 1833-1845.
36. O'Reilly, L.A., Huang, D.C.S., Strasser, A., 1996. The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J. 15, 6979-6990.
37. Prisco, M., Hongo, A., Rizzo, M.G., Sacchi, A., Baserga, R., 1997. The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol. Cell Biol. 3, 1084-1092.
38. Prives, C., Hall, P.A., 1999. The p53 pathway. J. Pathol. 187, 112-126.
39. Raff, M.C., 1992. Social controls on cell survival and cell death. Nature 356, 397-399.
40. Reed, J.C., 1994. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124, 1-6.
41. Rodel, J.E., Link, D.C., 1996. Suppression of apoptosis during cytokine deprivation of 32D cells is not sufficient to induce complete granulocytic differentiation. Blood 87, 858-864.
42. Sakaguchi, K., Herrera, J.E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C.W., Appella, E., 1998. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 12, 2831-2841.
43. Shieh, S.Y., Ikeda, M., Taya, Y., Prives, C., 1997. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334.
44. Shieh, S.Y., Taya, Y., Prives, C., 1999. DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization. EMBO J. 18, 1815-1823.
45. Siliciano, J.D., Canman, C.E., Taya, Y., Sakaguchi, K., Appella, E., Kastan, M.B., 1997. DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev. 11, 3471-3481.
46. Steller, H., 1995. Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
47. Thompson, C.B., 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
48. Vogelstein, B., Lane, D., Levine, A.J., 2000. Surfing the p53 network. Nature 408, 307-310.
49. Wei, M.C., Zong, W.X., Cheng, E.H., Lindsten, T., Panoutsakopoulou, V., Ross, A.J., Roth, K.A., MacGregor, G.R., Thompson, C.B., Korsmeyer, S.J., 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292, 727-730.
50. Wyllie, A., 1997. Apoptosis-clues in the p53 murder mystery. Nature 389, 237-238.
51. Yonish-Rouach, E., 1996. The p53 tumor suppressor gene: a mediator of a G1 growth arrest and of apoptosis. Experientia 52, 1001-1007.
52. Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., Oren, M., 1991. Wild-type p53 induces apoptosis of myeloid leukemia cells that is inhibited by interleukin 6. Nature 352, 345-347.
53. Zantema, A., Fransen, J.A.M., Davis-Olivier, A., Ramaekers, F.C.S., Vooijs, G.P., DeLeys, B., Van Der Eb, A.J., 1985a. Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies. Virology 142, 44-58.
54. Zantema, A., Schrier, P.I., Davis-Olivier, A., Van Laar, T., Vaessen, R.T.M.J., Van Der Eb, A.J., 1985b. Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells. Mol. Cell Biol. 5, 3084-3091.
55. Zhu, Y.M., Bradbury, D.A., Russell, N.H., 1994. Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukemic cells. Br. J. Cancer 69, 468-472.