Phosphodiesterase 4 inhibitors prevent cytokine secretion by T lymphocytes by inhibiting nuclear factor-κB and nuclear factor of activated T cells activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 2, 2001, Pages 753-759

  Bradley, Karri K ^a   Bradley, Michael E ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 5; NUCLEAR FACTOR; PENTOXIFYLLINE; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; BIOTRANSFORMATION; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; DNA-BINDING PROTEINS; ELECTROPHORESIS; HUMANS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHOSPHODIESTERASE INHIBITORS; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0034763008     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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