A review of dsb induction data for varying quality radiations

International Journal of Radiation Biology

Volumn 74, Issue 2, 1998, Pages 173-184

  Prise, K M ^a   Ahnstrom G ^b   Belli, M ^c   Carlsson, J ^d   Frankenberg, D ^e   Kiefer, J ^f   Lobrich M ^f   Michael, B D ^a   Nygren, J ^b   Simone, G ^c   Stenerlow B ^d  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c INFN SEZIONE DI ROMA   (Italy)

^d UPPSALA UNIVERSITY   (Sweden)

^e UNIVERSITY OF GÖTTINGEN   (Germany)

^f JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA STRAND BREAKAGE; DOSE RESPONSE; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RADIATION DOSE; RADIATION INJURY; REVIEW;

ALKALIES; CELL LINE; CELL SURVIVAL; CENTRIFUGATION, DENSITY GRADIENT; DNA; DNA DAMAGE; ELECTROPHORESIS, AGAR GEL; ELECTROPHORESIS, GEL, PULSED-FIELD; LINEAR ENERGY TRANSFER; RADIATION, IONIZING; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 0038805063     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530098141564     Document Type: Review

References (80)

1. AHNSTRÖM, G. and EDVARDSSON, K. A., 1974, Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxyapatite chromatography: an alternative to velocity sedimentation. International Journal of Radiation Biology, 26, 493-497.
2. AHNSTRÖM, G. and ERIXON, K., 1981, Measurement of strand breaks by alkaline denaturation and hydroxyapatite chromatography. In DNA Repair, Vol. 1, edited by E. C. Friedberg and P. C. Hanawalt (New York: Dekker), pp. 403-418.
3. AKPA, T. C., WEBER, K. J., SCHNEIDER, E., KIEFER, J., FRANKENBERG-SCHWAGER, M., HARBICH, R. and FRANKENBERG, D., 1992, Heavy ion-induced DNA double-strand breaks in yeast. International Journal of Radiation Biology, 62, 279-287.
4. BELLI, M., CERA, F., CHERUBINI, R., IANZINI, F., MOSCHINI, G., SAPORA, O., SIMONE, G., TABOCCHINI, M. A. and TIVERON, P., 1994, DNA double-strand breaks induced by low energy protons in V79 cells. International Journal of Radiation Biology, 65, 529-536.
5. BLÖCHER, D., 1982, DNA double-strand breaks in Ehrlich ascites tumour cells at low doses of X-rays. I. Determination of induced breaks by centrifugation at reduced speed. International Journal of Radiation Biology, 42, 317-328.
6. BLÖCHER, D., 1988, DNA double-strand break repair determines the RBE of α-particles. International Journal of Radiation Biology, 54, 761-771.
7. BLÖCHER, D., 1990, In CHEF electrophoresis a linear induction of dsb corresponds to a nonlinear fraction of extracted DNA with dose. International Journal of Radiation Biology, 57, 7-12.
8. BLÖCHER, D. and ILIAKIS, G., 1991, Size distribution of DNA molecules recovered from non-denaturing filter elution. International Journal of Radiation Biology, 59, 919-926.
9. BOTCHWAY, S. W., STEVENS, D. L., HILL, M. A., JENNER, T. J. and O'NEILL, P., 1997, Induction and rejoining of DNA double-strand breaks in Chinese hamster V79-4 cells irradiated with characteristic aluminium K and copper L ultrasoft x-rays. Radiation Research, 148, 317-324.
10. BRADLEY, M. O. and KOHN, K. W., 1979, X-ray induced DNA double-strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Research, 7, 793-804.
11. CEDERVALL, B. and KALLMAN, P., 1994, Randomly distributed DNA double strand breaks as measured by pulsed field gel electrophoresis: a series of explanatory calculations. Radiation and Environmental Biophysics, 33, 9-21.
12. CEDERVALL, B., WONG, R., ALBRIGHT, N., DYNLACHT, J., LAMBIN, P. and DEWEY, W. C., 1995, Methods for the quantification of DNA double-strand breaks determined from the distribution of DNA fragment sizes measured by pulsed-field gel electrophoresis. Radiation Research, 143, 8-16.
13. CHIA, D. and SCHUMAKER, V. N., 1974, A rotor speed dependent crossover on sedimentation velocities of DNAs of different sizes. Biochemical and Biophysical Research Communications, 56, 241-246.
14. 20,w, an examination of measurement problems. Biochimica et Biophysica Acta, 454, 567-577.
15. CLARK, R. W. and LANGE, C. S., 1980, A quantitative test of Zimm's model for the rotor-speed dependent sedimentation of linear DNA molecules. Biopolymers, 19, 945-964.
16. COLE, A., MEYN, R. E., CHEN, R., CORBY, P. M. and HITTELMAN, W., 1980, Mechanisms for cell injury. In Radiation Biology in Cancer Research, edited by R. E. Meyn and H. R. Withers (New York: Raven Press), pp. 33-58.
17. COOK, V. E. and MORTIMER, R. K., 1991, A quantitative model of DNA fragments generated by ionizing radiation, and possible experimental application. Radiation Research, 125, 102-106.
18. 241Am α-particles or bleomycin. International Journal of Radiation Biology, 51, 209-218.
19. CORRY, P. M. and COLE, A., 1973, Double-strand rejoining in mammalian cells. Nature New Biology, 245, 100-101.
20. DAHM-DAPHI, J. and DIKOMEY, E., 1995, Separation of DNA fragments induced by ionizing irradiation using a gradedfield gel electrophoresis. International Journal of Radiation Biology, 67, 161-168.
21. EIGNER, J. and DOTY, P., 1965, The native, denatured and renatured status of deoxyribonucleic acid. Journal of Molecular Biology, 12, 549-580.
22. ERIXON, K., CEDERVALL, B. and LEWENSOHN, R., 1990, Pulsed-field gel electrophoresis for measuring radiation-induced DNA double-strand breaks. Comparison to the method of neutral filter elution. In Ionizing Radiation Damage to DNA: Molecular Aspects, edited by S. S. Wallace and R. B. Painter (New York: Wiley), pp. 69-80.
23. FANGMAN, W. L., 1978, Separation of very large molecules by gel electrophoresis. Nucleic Acid Research, 5, 653-665.
24. FORNACE, A. J., 1982, Detection of DNA single-strand breaks produced during the repair of damage by DNA-protein cross linking agents. Cancer Research, 42, 145-149.
25. FOX, R. A., 1976, The analysis of single-strand breaks in E. coli using a curve-fitting procedure. International Journal of Radiation Biology, 30, 67-78.
26. 238Pu α-particles: evidences for a fast component of repair as measured by neutral filter elution. International Journal of Radiation Biology, 57, 513-521.
27. FRANKENBERG, D., FRANKENBERG-SCHWAGER, M., BLOCHER, D. and ADAMCZYK, C., 1981a, Initial and irreparable double-strand breaks in the DNA of irradiated eukaryotic cells in dependence of dose rate and LET; implications for survival studies. In Proceedings of the Seventh Symposium on Microdosimetry, Vol. II, edited by J. Booz, H. G. Ebert and H. D. Hartfield (Chur: Harwood Academic Publishers), pp. 1033-1042.
28. FRANKENBERG, D., FRANKENBERG-SCHWAGER, M., BLOCHER, D. and HARBICH, R., 1981b, Evidence for DNA double-strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiation under oxic or anoxic conditions. Radiation Research, 88, 524-532.
29. FRANKENBERG, D., GOODHEAD, D. T., FRANKENBERG-SCHWAGER, M., HARBICH, R., BANCE, D. A. and WILKINSON, R. E., 1986, Effectiveness of 1.5 keV aluminium K and 0.3 keV carbon K characteristic X-rays at inducing DNA double-strand breaks in yeast cells. International Journal of Radiation Biology, 50, 727-741.
30. GRAY, H. B., BLOOMFIELD, V. A. and HEARST, J. E., 1967, Sedimentation coefficients of linear and cyclic Wormlike coils with excluded-volume effects. Journal of Chemistry and Physics, 46, 1493-1496.
31. HEILMANN, J., TAUCHER-SCHOLZ, G. and KRAFT, G., 1995, Induction of DNA double-strand breaks in CHO-K1 cells by carbon ions. International Journal of Radiation Biology, 68, 153-162.
32. HUTCHINSON, F. and KRASIN, F., 1977, Dependence of the sedimentation of high molecular weight DNA on centrifuge speed. Biophysical Chemistry, 6, 23-29.
33. IKPEME, S., LÖBRICH, M., AKPA, T., SCHNEIDER, E. and KIEFER, J., 1995, Heavy ion-induced DNA double-strand breaks with yeast as a model system. Radiation and Environmental Biophysics, 34, 95-99.
34. JENNER, T. J., BELLI, M., GOODHEAD, D. T., IANZINI, F., SIMONE, G. and TABOCCHINI, M. A., 1992, Direct comparison of biological effectiveness of protons and alpha-particles of the same LET. III. Initial yield of DNA double-strand breaks in V79 cells. International Journal of Radiation Biology, 61, 631-637.
35. JENNER, T. J., DELARA, C. M., O'NEILL, P. and STEVENS, D. L., 1993, Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following γ- and α-irradiation. International Journal of Radiation Biology, 64, 265-273.
36. JOSTES, R. F., HUI, T. E. and CROSS, F. L., 1993, Single-cell gel techniques support hit probability calculations. Health Physics, 64, 675-679.
37. KAMPF, G. and EICHHORN, K., 1983, DNA strand breakage by different radiation qualities and relations to cell killing: further results after the influence of α-particles and carbon ions. Studia Biophysica, 93, 17-26.
38. KODYM, R. and HORTH, E., 1995, Determination of radiation-induced DNA strand breaks in individual cells by non-radioactive labelling of 3′ OH ends. International Journal of Radiation Biology, 68, 133-139.
39. KOHN, K. W. and EWIG, R. A. G., 1973, Elution analysis: a new approach to the study of DNA single-strand interruptions in cells. Cancer Research, 33, 1849-1853.
40. KOHN, K. W. and EWIG, R. A., 1979, DNA-protein crosslinking by trans-platinum(II)diamminedichloride in mammalian cells, a new method of analysis. Biochimica et Biophysica Acta, 562, 32-40.
41. KYSELA, B. P., ARRAND, J. E. and MICHAEL, B. D., 1993, Relative contributions of levels of initial damage and repair of double-strand breaks to the ionizing radiation-sensitive phenotype of the Chinese hamster cell mutant XR-V15B. Part II Neutrons. International Journal of Radiation Biology, 64, 531-538.
42. LANGE, C. S., 1974, The organization and repair of mammalian DNA. FEBS Letters, 44, 153-156.
43. LANGE, C. S., COLE, A. and OSTASHEVSKY, J. Y., 1993, Radiation-induced damage in chromosomal DNA molecules: deduction of chromosomal organization from the hydrodynamic data used to measure DNA double-strand breaks and from stereo electron microscopic observations. Advances in Radiation Biology, 17, 261-421.
44. LANGE, C. S., LIBERMAN, D. F., CLARK, R. W. and FERGUSON, P., 1977, The organization and repair of DNA in the mammalian chromosome; I. Calibration procedures and errors in the determination of the molecular weight of a native DNA. Biopolymers, 16, 1063-1081.
45. LEHMANN, A. R. and ORMEROD, M. G., 1970, Double-strand breaks in the DNA of a mammalian cell after X-irradiation. Biochimica et Biophysica Acta, 217, 268-277.
46. LITWIN, S., 1969, Distribution of radioactive recovery in randomly cut sediment DNA. Journal of Applied Probability, 6, 275-284.
47. LÖBRICH, M., COOPER, P. K. and RYDBERG, B., 1996, Non-random distribution of DNA double-strand breaks induced by particle irradiation. International Journal of Radiation Biology, 70, 493-503.
48. LÖBRICH, M., IKPEME, S., HAUB, P., WEBER, K.-J. and KIEFER, J., 1993, DNA double-strand break induction in yeast by X-rays and α-particles measured by pulsed-field gel-electrophoresis. International Journal of Radiation Biology, 64, 539-546.
49. LÖBRICH, M., IKPEME, S. and KIEFER, J., 1994a, Measurement of DNA double-strand breaks in mammalian cells by pulsed-field gel electrophoresis: a new approach using rarely cutting restriction enzymes. Radiation Research, 138, 186-192.
50. LÖBRICH, M., IKPEME, S. and KIEFER, J., 1995, DNA double-strand break measurement in mammalian cells by pulsed-field gel electrophoresis: an approach using restriction enzymes and gene probing. International Journal of Radiation Biology, 65, 623-630.
51. LÖBRICH, M., RYDBERG, B. and COOPER, P. K., 1994b, DNA double-strand breaks induced by high-energy neon and iron ions in human fibroblasts. II. Probing individual NotI fragments by hybridization. Radiation Research, 139, 142-151.
52. LONGO, J. A., NEVALDINE, B., LONGO, S. L., WINFIELD, J. A. and HAHN, P. J., 1997, An assay quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells. Radiation Research, 147, 35-40.
53. MAYER, P. J., LANGE, C. S., BRADLEY, M. O. and NICHOLS, W. W., 1991, Investigation of the neutral filter elution technique. 1. Effects of pore density and pore diameter on elution rate at ph 9.6. Radiation Research, 125, 197-205.
54. MCGRATH, R. A. and WILLIAMS, R. W., 1966, Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature, 212, 534-535.
55. MONTROLL, E. W. and SIMHA, R., 1940, Theory of depolymerization of long chain molecules. Journal of Chemical Physics, 8, 721-727.
56. NEWMAN, H. C., PRISE, K. M., FOLKARD, M. and MICHAEL, B. D., 1997, DNA double-strand break distributions in X-ray and α-particle irradiated V79 cells: evidence for non-random breakage. International Journal of Radiation Biology, 71, 347-363.
57. NYGREN, J. and AHNSTRÖM, G., 1992, The filter does not act as a DNA size discriminator in the neutral filter elution technique. International Journal of Radiation Biology, 62, 397-399.
58. 6+ ions in human cells: relative biological effectiveness is dependent on the relative contribution of the direct and indirect effects. International Journal of Radiation Biology, 70, 421-427.
59. OKAYASU, R. and ILIAKIS, G., 1989, Linear DNA elution dose response curves obtained in CHO cells with non-unwinding filter elution after appropriate selection of lysis conditions. International Journal of Radiation Biology, 55, 569-581.
60. OLIVE, P. L., WLODEK, D. and BANATH, J. P., 1991, DNA double strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Research, 51, 4671-4676.
61. ÖSTLING, O. and JOHANSON, K. J., 1984, Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochemical and Biophysical Research Communications, 123, 291-298.
62. POLLER, F., BAUCH, T., SAUERWEIN, W., BOCKER, W., WITTIG, A. and STREFFER, C., 1996, Comet assay study of DNA damage and repair of tumour cells following boron neutron capture irradiation with fast d(14) + Be neutrons. International Journal of Radiation Biology, 70, 593-602.
63. PRISE, K. M., DAVIES, S. and MICHAEL, B. D., 1987, The relationship between radiation-induced DNA double-strand breaks and cell kill in hamster V79 fibroblasts irradiated with 250KVp X-rays, 2.3 MeV neutrons or 238Pu α-particles. International Journal of Radiation Biology, 52, 893-902.
64. PRISE, K. M., FOLKARD, M., DAVIES, S. and MICHAEL, B. D., 1989, Measurement of DNA damage and cell killing in Chinese hamster V79 cells irradiated with aluminium characteristic ultrasoft X-rays. Radiation Research, 117, 489-499.
65. PRISE, K. M., FOLKARD, M., VOJNOVIC, B., DAVIES, S., ROPER, M. J. and MICHAEL, B. D., 1990, The irradiation of V79 mammalian cells by protons with energies below 2MeV. Part II: measurement of oxygen enhancement ratios and DNA damage. International Journal of Radiation Biology, 58, 261-277.
66. RADFORD, I. R., 1985, The level of induced UNA double-strand breakage correlates with cell killing after X-irradiation. International Journal of Radiation Biology, 48, 45-54.
67. RADFORD, I. R. and HODGSON, G. S., 1985, 125-I Induced DNA double strand breaks: use in calibration of the neutral filter clution technique and comparison with X-ray induced breaks. International Journal of Radiation Biology, 48, 555-566.
68. Ross, G. M., EADY, J. J., MITHAL, N. P., BUSH, C., STEEL, G. G., JEGGO, P. A. and MCMILLAN, T. J., 1995, DNA strand break rejoining defect in xrs-6 is complemented by transfection with the human Ku80 gene. Cancer Research, 55, 1235-1238.
69. RYDBERG, B., 1996, Clusters of DNA damage induced by ionizing radiation: formation of short DNA fragments. II. Experimental detection. Radiation Research, 145, 200-209.
70. RYDBERG, B., LÖBRICH, M. and COOPER, P. K., 1994, DNA double-strand breaks induced by high-energy neon and iron ions in human fibroblasts. I. Pulsed-field gel electrophoresis method. Radiation Research, 139, 133-141.
71. SAK, A., STUSCHKE, M., STAPPER, N. and STREFFER, C., 1996, Induction of DNA double-strand breaks by ionizing radiation at the c-myc locus compared with the whole genome: a study using pulsed-field gel electrophoresis and gene probing. International Journal of Radiation Biology, 69, 679-685.
72. SCHWARTZ, D. C. and CANTOR, C. R., 1984, Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell, 37, 67-75.
73. SINGH, N. P., MCCOY, M. T., TICE, R. R. and SCHNEIDER, E. L., 1988, A simple technique for quantitation of low levels of DNA damage in individual cell. Experimental Cell Research, 175, 184-191.
74. STENERLÖW, B., BLOMQUIST, E., GRUSELL, E., HARTMAN, T. and CARLSSON, J., 1996, Rejoining of DNA double-strand breaks induced by accelerated nitrogen ions. International Journal of Radiation Biology, 70, 413-420.
75. STENERLÖW, B., CARLSSON, J., BLOMQUIST, E. and ERIXON, K., 1994, Clonogenic survival and rejoining of DNA double-strand breaks: comparisons between three cell lines after photon or He ion irradiation. International Journal of Radiation Biology, 65, 631-639.
76. SUTHERLAND, B. M., BENNETT, P. V. and SUTHERLAND, J. C., 1996, Double strand breaks induced by low doses of γ rays or heavy ions: quantitation in nonradioactive DNA. Analytical Biochemistry, 239, 53-60.
77. WEBER, K. J. and FLENTJE, M., 1993, Lethality of heavy ion-induced DNA double-strand breaks in mammalian cells. International Journal of Radiation Biology, 64, 169-178.
78. WLODEK, D., BANATH, J. and OLIVE, P., 1991, Comparison between pulsed-field and constant-field gel electrophoresis for measurement of DNA double-strand breaks in irradiated Chinese hamster ovary cells. International Journal of Radiation Biology, 60, 779-790.
79. WLODEK, D. and OLIVE, P. L., 1990, Physical basis for detection of DNA double-strand breaks using neutral filter elution. Radiation Research, 124, 326-333.
80. ZIMM, B. H., 1974, Anormalities in sedimentation; IV. Decrease in sedimentation coefficients of chains at high fields. Biophysical Chemistry, 1, 279-291.